PANTHER Gene Information   
Gene Symbol(s): PRKAR1A
Organism: Bos taurus
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Gene Name: cAMP-dependent protein kinase type I-alpha regulatory subunit
Gene ID: ENSBTAG00000008621
Protein ID: P00514
Persistent Id: PTN007520929
Alternate Ids:
ENSBTAP00000011371(Ensembl_PRO) Q17QP8(AltAccession)
285803278(GI) PRKAR1A(Symbol)
AAA30708(EMBL-CDS) 615074(GeneID)
KAP0_BOVIN(UniProtKB-ID) NP_001069826(refSeq)
KAP0(Synonym) BT030573(EMBL)
ENSBTAG00000008621(Ensembl) ENSBTAT00000011371(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN (PTHR11635)
PANTHER Subfamily: CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT (PTHR11635:SF129)  
PANTHER GO-slim Molecular Function: protein kinase binding
protein kinase A binding
protein kinase inhibitor activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of protein serine/threonine kinase activity
negative regulation of protein kinase activity
PANTHER GO-slim Cellular Component: serine/threonine protein kinase complex
intracellular protein-containing complex
cytosol
PANTHER protein class: kinase modulator
Pathway Categories: Metabotropic glutamate receptor group I pathway
   Protein kinase A
Metabotropic glutamate receptor group II pathway
   Protein kinase A
GABA-B receptor II signaling
   Protein kinase A
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Protein kinase A
Transcription regulation by bZIP transcription factor
   Protein kinase A
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Protein kinase A, regulatory subunit
Endothelin signaling pathway
   Protein kinase A
Hedgehog signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group III pathway
   Protein kinase A
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein domain specific binding, identical protein binding, protein binding, ubiquitin protein ligase binding, protein kinase A catalytic subunit binding, cAMP binding, cAMP-dependent protein kinase inhibitor activity
GO BP Complete: negative regulation of cAMP/PKA signal transduction, negative regulation of gene expression, cellular response to glucagon stimulus, sarcomere organization, negative regulation of activated T cell proliferation, mesoderm formation, adenylate cyclase-activating G protein-coupled receptor signaling pathway, positive regulation of insulin secretion, cardiac muscle cell proliferation
GO CC Complete: centrosome, sperm head-tail coupling apparatus, cytoplasm, cytosol, neuromuscular junction, multivesicular body, glutamatergic synapse, plasma membrane raft, axoneme, cAMP-dependent protein kinase complex, immunological synapse, nucleotide-activated protein kinase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Factors involved in megakaryocyte development and platelet production, Intracellular signaling by second messengers, DARPP-32 events, Signal Transduction, Activation of NMDA receptors and postsynaptic events, Metabolism, Hemostasis, Hedgehog 'off' state, Aquaporin-mediated transport, PKA-mediated phosphorylation of CREB, CaM pathway, Ca-dependent events, G-protein mediated events, PLC beta mediated events, G alpha (i) signalling events, Calmodulin induced events, Post NMDA receptor activation events, Transport of small molecules, PKA activation in glucagon signalling, CREB1 phosphorylation through the activation of Adenylate Cyclase, Integration of energy metabolism, GPCR downstream signalling, Signaling by GPCR, DAG and IP3 signaling, Glucagon signaling in metabolic regulation, Opioid Signalling, Transmission across Chemical Synapses, PKA activation, Neuronal System, Vasopressin regulates renal water homeostasis via Aquaporins, Neurotransmitter receptors and postsynaptic signal transmission, G alpha (s) signalling events, Signaling by Hedgehog, GPER1 signaling

Orthologs