PANTHER Gene Information   
Gene Symbol(s): Prkar2b
Organism: Rattus norvegicus
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Gene Name: cAMP-dependent protein kinase type II-beta regulatory subunit
Gene ID: 3394
Protein ID: P12369
Persistent Id: PTN000180644
Alternate Ids:
NM_001030020(refSeq) 544192009(GI)
ENSRNOP00000012415(Ensembl_PRO) KAP3_RAT(UniProtKB-ID)
Prkar2b(Symbol) 3394(RGD)
KAP3(Synonym) ENSRNOT00000012415(Ensembl_TRS)
AAA42047(EMBL-CDS) ENSRNOG00000009079(Ensembl)
24679(GeneID) M12492(EMBL)
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PANTHER Classification
PANTHER Family: CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN (PTHR11635)
PANTHER Subfamily: CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT (PTHR11635:SF156)  
PANTHER GO-slim Molecular Function: protein kinase binding
protein kinase A binding
protein kinase inhibitor activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of protein serine/threonine kinase activity
negative regulation of protein kinase activity
PANTHER GO-slim Cellular Component: serine/threonine protein kinase complex
intracellular protein-containing complex
cytosol
PANTHER protein class: kinase modulator
Pathway Categories: Metabotropic glutamate receptor group II pathway
   Protein kinase A
GABA-B receptor II signaling
   Protein kinase A
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Protein kinase A
Transcription regulation by bZIP transcription factor
   Protein kinase A
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Protein kinase A, regulatory subunit
Endothelin signaling pathway
   Protein kinase A
Enkephalin release
   Protein kinase A
Beta1 adrenergic receptor signaling pathway
   Protein kinase A
Hedgehog signaling pathway
   Protein kinase A
Dopamine receptor mediated signaling pathway
   Protein kinase A
5HT1 type receptor mediated signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group III pathway
   Protein kinase A
Histamine H2 receptor mediated signaling pathway
   Protein kinase A
Beta2 adrenergic receptor signaling pathway
   Protein kinase A
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, protein domain specific binding, protein binding, ubiquitin protein ligase binding, protein kinase A catalytic subunit binding, cAMP binding, cAMP-dependent protein kinase regulator activity, kinase activity, cAMP-dependent protein kinase inhibitor activity
GO BP Complete: negative regulation of cAMP/PKA signal transduction, regulation of protein kinase activity, response to antipsychotic drug, modulation of chemical synaptic transmission, adenylate cyclase-activating G protein-coupled receptor signaling pathway, learning, fatty acid metabolic process
GO CC Complete: neuronal cell body, plasma membrane, cAMP-dependent protein kinase complex, dendrite, centrosome, perinuclear region of cytoplasm, postsynapse, cytoplasm, dendritic shaft, ciliary base, dendritic spine, cytosol, glutamatergic synapse
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Integration of energy metabolism, PKA activation in glucagon signalling, DARPP-32 events, Opioid Signalling, Factors involved in megakaryocyte development and platelet production, Recruitment of NuMA to mitotic centrosomes, Centrosome maturation, Loss of proteins required for interphase microtubule organization from the centrosome, AURKA Activation by TPX2, Post NMDA receptor activation events, Vasopressin regulates renal water homeostasis via Aquaporins, Cell Cycle, M Phase, Calmodulin induced events, PKA-mediated phosphorylation of CREB, GPCR downstream signalling, GPER1 signaling, Recruitment of mitotic centrosome proteins and complexes, CREB1 phosphorylation through the activation of Adenylate Cyclase, Mitotic Prometaphase, Aquaporin-mediated transport, Signaling by GPCR, Regulation of PLK1 Activity at G2/M Transition, Loss of Nlp from mitotic centrosomes, Signaling by Hedgehog, Hemostasis, Anchoring of the basal body to the plasma membrane, Neuronal System, Transmission across Chemical Synapses, Neurotransmitter receptors and postsynaptic signal transmission, G alpha (i) signalling events, G alpha (s) signalling events, Activation of NMDA receptors and postsynaptic events, Organelle biogenesis and maintenance, PKA activation, Cilium Assembly, Glucagon signaling in metabolic regulation, Cell Cycle, Mitotic, Hedgehog 'off' state, DAG and IP3 signaling, G2/M Transition, PLC beta mediated events, Signal Transduction, Ca-dependent events, CaM pathway, Metabolism, G-protein mediated events, Intracellular signaling by second messengers, Transport of small molecules, Mitotic G2-G2/M phases

Orthologs