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Gene Symbol(s):
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Fgf2
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| Organism: |
Rattus norvegicus |
| View Gene in Tree |
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| Gene Name: |
Fibroblast growth factor 2
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| Gene ID: |
2609
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| Protein ID: |
P13109
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| Persistent Id: |
PTN000160336 |
| Alternate Ids: |
| 56204(GI) |
ENSRNOG00000017392(Ensembl) |
| Fgf2(Symbol) |
bFGF(Synonym) |
| ENSRNOT00000023388(Ensembl_TRS) |
54250(GeneID) |
| NP_062178(refSeq) |
CAA30265(EMBL-CDS) |
| 2609(RGD) |
ENSRNOP00000023388(Ensembl_PRO) |
| FGF2_RAT(UniProtKB-ID) |
X07285(EMBL) |
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Show All
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| GO MF Complete: |
receptor-receptor interaction, chemokine binding, growth factor activity, identical protein binding, protein binding, nuclear receptor coactivator activity, chemoattractant activity, H3K9me3 modified histone binding, integrin binding, heparin binding, cytokine activity, fibroblast growth factor receptor binding
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| GO BP Complete: |
positive regulation of cardiac muscle cell proliferation, neuroepithelial cell differentiation, positive chemotaxis, embryo development ending in birth or egg hatching, positive regulation of inner ear auditory receptor cell differentiation, thyroid-stimulating hormone-secreting cell differentiation, lymphatic endothelial cell migration, transcription by RNA polymerase II, fibroblast growth factor receptor signaling pathway, cell migration involved in sprouting angiogenesis, neurogenesis, animal organ development, response to axon injury, endothelial cell migration, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of neuroepithelial cell differentiation, positive regulation of angiogenesis, mammary gland epithelial cell differentiation, corticotropin hormone secreting cell differentiation, neuroblast proliferation, wound healing, epithelial cell proliferation, positive regulation of DNA-templated transcription, release of sequestered calcium ion into cytosol, regulation of cell cycle, positive regulation of epithelial cell proliferation, negative regulation of wound healing, negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, chondroblast differentiation, positive regulation of epithelial tube formation, positive regulation of cerebellar granule cell precursor proliferation, positive regulation of cell fate specification, positive regulation of canonical Wnt signaling pathway, positive regulation of neuroblast proliferation, regulation of retinal cell programmed cell death, negative regulation of stem cell proliferation, positive regulation of gene expression, positive regulation of stem cell proliferation, organ induction, regulation of cell migration, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, hyaluronan catabolic process, cell population proliferation, positive regulation of MAP kinase activity, negative regulation of cell population proliferation, positive regulation of cell population proliferation, positive regulation of vascular endothelial cell proliferation, cerebellar granule cell precursor proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription by RNA polymerase II, positive regulation of smooth muscle cell proliferation, positive regulation of stem cell differentiation, response to ethanol, phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of vascular associated smooth muscle cell proliferation, stem cell differentiation, positive regulation of cell division, angiogenesis, stem cell proliferation, osteoblast differentiation, canonical Wnt signaling pathway, positive regulation of endothelial cell chemotaxis, positive regulation of endothelial cell migration, positive regulation of DNA biosynthetic process, lung development, negative regulation of blood vessel endothelial cell migration, signal transduction, positive regulation of sprouting angiogenesis, paracrine signaling, angiogenesis involved in coronary vascular morphogenesis, positive regulation of MAPK cascade, behavioral response to ethanol, stem cell development, response to wortmannin, positive regulation of lens fiber cell differentiation, substantia nigra development, positive regulation of blood vessel endothelial cell migration, ERK1 and ERK2 cascade, cellular response to mechanical stimulus, inner ear auditory receptor cell differentiation, branching involved in ureteric bud morphogenesis, positive regulation of protein phosphorylation, positive regulation of ERK1 and ERK2 cascade, endothelial cell proliferation, cell differentiation, negative regulation of fibroblast migration, regulation of endothelial cell chemotaxis to fibroblast growth factor, positive regulation of endothelial cell proliferation, positive regulation of endothelial cell chemotaxis to fibroblast growth factor, glial cell differentiation, growth factor dependent regulation of skeletal muscle satellite cell proliferation
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| GO CC Complete: |
nucleus, extracellular space, cytoplasm, extracellular region
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| Reactome Pathways: |
Signaling by Insulin receptor, Insulin receptor signalling cascade, Downstream signaling of activated FGFR3, FRS-mediated FGFR3 signaling, IRS-related events triggered by IGF1R, FRS-mediated FGFR2 signaling, Phospholipase C-mediated cascade; FGFR3, Phospholipase C-mediated cascade; FGFR4, Signaling by FGFR4, SHC-mediated cascade:FGFR3, FGFR3 ligand binding and activation, Signaling by FGFR, SHC-mediated cascade:FGFR4, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Negative regulation of the PI3K/AKT network, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), FRS-mediated FGFR4 signaling, FGFR2 ligand binding and activation, PI-3K cascade:FGFR3, FGFR1 ligand binding and activation, Downstream signaling of activated FGFR4, FRS-mediated FGFR1 signaling, IRS-mediated signalling, Downstream signaling of activated FGFR2, MAPK family signaling cascades, FGFR4 ligand binding and activation, PI-3K cascade:FGFR2, PIP3 activates AKT signaling, Extracellular matrix organization, Syndecan interactions, Non-integrin membrane-ECM interactions, PI-3K cascade:FGFR1, Signaling by Receptor Tyrosine Kinases, FGFR2c ligand binding and activation, PI-3K cascade:FGFR4, PI3K Cascade, Downstream signaling of activated FGFR1, SHC-mediated cascade:FGFR1, FGFR1c ligand binding and activation, Negative regulation of FGFR1 signaling, FGFR3c ligand binding and activation, Negative regulation of FGFR2 signaling, FGFR1b ligand binding and activation, MAPK1/MAPK3 signaling, FGFRL1 modulation of FGFR1 signaling, Signaling by FGFR3, Phospholipase C-mediated cascade; FGFR2, FGFR2b ligand binding and activation, Signal Transduction, RAF/MAP kinase cascade, IGF1R signaling cascade, Negative regulation of FGFR4 signaling, Intracellular signaling by second messengers, Negative regulation of FGFR3 signaling, SHC-mediated cascade:FGFR2, Signaling by FGFR2, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1
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