PANTHER Gene Information   
Gene Symbol(s): FGF1
Organism: Gallus gallus
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Gene Name: Fibroblast growth factor 1
Gene ID: ENSGALG00010013399
Protein ID: P19596
Persistent Id: PTN000160320
Alternate Ids:
Heparin-binding growth factor 1(Synonym) 1345988(GI)
AAD13942(EMBL-CDS) ENSGALT00015051391(Ensembl_TRS)
396094(GeneID) ENSGALP00010019052(Ensembl_PRO)
FGF1_CHICK(UniProtKB-ID) XP_015149495(refSeq)
S63261(EMBL) ENSGALG00015021086(Ensembl)
FGF1(Symbol)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 1 (PTHR11486:SF86)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
fibroblast growth factor receptor signaling pathway
cell differentiation
positive regulation of protein serine/threonine kinase activity
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
regulation of MAP kinase activity
PANTHER GO-slim Cellular Component: extracellular space
nucleus
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: Angiogenesis
   Fibroblast Growth Factor
FGF signaling pathway
   fibroblast growth factor

GO MF Complete: growth factor activity, integrin binding, heparin binding, S100 protein binding, fibroblast growth factor receptor binding
GO BP Complete: positive regulation of cell population proliferation, branch elongation involved in ureteric bud branching, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of cholesterol biosynthetic process, positive regulation of MAPK cascade, positive regulation of intracellular signal transduction, positive regulation of transcription by RNA polymerase II, positive regulation of angiogenesis, epicardial cell to mesenchymal cell transition, mesonephric epithelium development, positive regulation of cell division, angiogenesis, regulation of cell migration, positive regulation of cell migration
GO CC Complete: nucleus, extracellular space, cytoplasm, cell cortex, cytosol, extracellular region
Reactome Pathways: FGFR1 ligand binding and activation, FGFR2 ligand binding and activation, Negative regulation of the PI3K/AKT network, Intracellular signaling by second messengers, Signaling by Insulin receptor, PI-3K cascade:FGFR4, Downstream signaling of activated FGFR1, SHC-mediated cascade:FGFR1, RAF/MAP kinase cascade, Negative regulation of FGFR1 signaling, Negative regulation of FGFR2 signaling, PI-3K cascade:FGFR1, Insulin receptor signalling cascade, FGFR4 ligand binding and activation, SHC-mediated cascade:FGFR2, Negative regulation of FGFR3 signaling, Downstream signaling of activated FGFR2, Signaling by Receptor Tyrosine Kinases, PIP3 activates AKT signaling, PI-3K cascade:FGFR2, Signal Transduction, FRS-mediated FGFR1 signaling, Signaling by FGFR2, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1, Negative regulation of FGFR4 signaling, FGFR3 ligand binding and activation, Signaling by FGFR, MAPK1/MAPK3 signaling, Signaling by FGFR4, Signaling by FGFR3, Phospholipase C-mediated cascade; FGFR2, IGF1R signaling cascade, FRS-mediated FGFR3 signaling, IRS-related events triggered by IGF1R, SHC-mediated cascade:FGFR3, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, FRS-mediated FGFR2 signaling, Phospholipase C-mediated cascade; FGFR3, Phospholipase C-mediated cascade; FGFR4, Downstream signaling of activated FGFR3, FGFR1c ligand binding and activation, FGFR3c ligand binding and activation, FGFR3b ligand binding and activation, FGFR1b ligand binding and activation, PI-3K cascade:FGFR3, Downstream signaling of activated FGFR4, IRS-mediated signalling, FRS-mediated FGFR4 signaling, PI3K Cascade, FGFR2b ligand binding and activation, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), SHC-mediated cascade:FGFR4, FGFR2c ligand binding and activation, MAPK family signaling cascades