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Gene Symbol(s):
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PIK3R2
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| Organism: |
Bos taurus |
| View Gene in Tree |
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| Gene Name: |
Phosphatidylinositol 3-kinase regulatory subunit beta
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| Gene ID: |
ENSBTAG00000002350
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| Protein ID: |
P23726
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| Persistent Id: |
PTN000016408 |
| Alternate Ids: |
| PI3-kinase regulatory subunit beta(Synonym) |
PIK3R2(Symbol) |
| ENSBTAG00000002350(Ensembl) |
163479(GI) |
| AAI18114(EMBL-CDS) |
ENSBTAP00000003033(Ensembl_PRO) |
| NP_777001(refSeq) |
M61746(EMBL) |
| P85B_BOVIN(UniProtKB-ID) |
Q17QY7(AltAccession) |
| ENSBTAT00000003033(Ensembl_TRS) |
282308(GeneID) |
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Show All
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| GO MF Complete: |
phosphotyrosine residue binding, protein binding, protein phosphatase binding, phosphatidylinositol 3-kinase regulatory subunit binding, protein heterodimerization activity, receptor tyrosine kinase binding, 1-phosphatidylinositol-3-kinase regulator activity
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| GO BP Complete: |
regulation of protein localization to plasma membrane, positive regulation of protein import into nucleus, insulin receptor signaling pathway, negative regulation of MAPK cascade, protein transport, regulation of stress fiber assembly, positive regulation of cell adhesion, positive regulation of transcription by RNA polymerase II, regulation of actin filament polymerization, cellular response to insulin stimulus, phosphatidylinositol 3-kinase/protein kinase B signal transduction, intracellular glucose homeostasis, regulation of autophagy, response to endoplasmic reticulum stress
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| GO CC Complete: |
phosphatidylinositol 3-kinase complex, class IA, nucleus, focal adhesion
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| Reactome Pathways: |
CD28 co-stimulation, Cytokine Signaling in Immune system, Interleukin-3, Interleukin-5 and GM-CSF signaling, Signaling by Interleukins, Adaptive Immune System, Role of phospholipids in phagocytosis, CD28 dependent PI3K/Akt signaling, PI3K Cascade, Intracellular signaling by second messengers, Platelet activation, signaling and aggregation, Signal Transduction, Signaling by ALK, TCR signaling, Metabolism, Innate Immune System, Signaling by PDGF, Hemostasis, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Negative regulation of the PI3K/AKT network, RAF/MAP kinase cascade, Fcgamma receptor (FCGR) dependent phagocytosis, PIP3 activates AKT signaling, PI3K/AKT activation, RHO GTPase cycle, RHOJ GTPase cycle, Interleukin receptor SHC signaling, RAC2 GTPase cycle, Immune System, RHOD GTPase cycle, PI Metabolism, Insulin receptor signalling cascade, Phospholipid metabolism, Signaling by Insulin receptor, Role of LAT2/NTAL/LAB on calcium mobilization, Developmental Biology, GPCR downstream signalling, Signaling by SCF-KIT, Signaling by NTRK1 (TRKA), Extra-nuclear estrogen signaling, MAPK1/MAPK3 signaling, VEGFA-VEGFR2 Pathway, Signaling by Rho GTPases, Synthesis of PIPs at the plasma membrane, Regulation of signaling by CBL, Costimulation by the CD28 family, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, RET signaling, RND3 GTPase cycle, Interleukin-2 family signaling, Signaling by NTRKs, Downstream TCR signaling, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), GPVI-mediated activation cascade, Interleukin-7 signaling, RHOF GTPase cycle, IRS-related events triggered by IGF1R, IGF1R signaling cascade, RHOA GTPase cycle, RND1 GTPase cycle, Axon guidance, Signaling by Nuclear Receptors, RND2 GTPase cycle, Signaling by Receptor Tyrosine Kinases, Tie2 Signaling, RAC1 GTPase cycle, DAP12 interactions, RHOU GTPase cycle, Metabolism of lipids, DAP12 signaling, Cell surface interactions at the vascular wall, MAPK family signaling cascades, RAC3 GTPase cycle, CDC42 GTPase cycle, IRS-mediated signalling, Downstream signal transduction, Signaling by GPCR, ESR-mediated signaling, Fc epsilon receptor (FCERI) signaling, Signaling by VEGF, G alpha (q) signalling events, Nervous system development
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