PANTHER Gene Information

Gene Symbol(s):

pikA

Organism:

Dictyostelium discoideum

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Gene Name:

Phosphatidylinositol 3-kinase 1

Gene ID:

DDB_G0278727

Protein ID:

P54673

Persistent Id:

PTN000005888

Alternate Ids:

Q54XS5(AltAccession)	60469984(GI)
EAL67965(Ensembl_TRS)	XP_641955(refSeq)
2.7.1.137(EC)	U23476(EMBL)
DDB_G0278727(Ensembl)	AAA85721(EMBL-CDS)
EAL67965(Ensembl_PRO)	PI3K1_DICDI(UniProtKB-ID)
DDB_G0278727(dictyBase)	8621687(GeneID)
pikA(Symbol)	pik1(Synonym)
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PANTHER Classification

PANTHER Family:	PHOSPHATIDYLINOSITOL KINASE (PTHR10048)
PANTHER Subfamily:	LD28067P (PTHR10048:SF14)
PANTHER GO-slim Molecular Function:	lipid kinase activity phosphotransferase activity, alcohol group as acceptor
PANTHER GO-slim Biological Process:	cell migration phosphatidylinositol phosphate biosynthetic process phosphatidylinositol 3-kinase/protein kinase B signal transduction
PANTHER GO-slim Cellular Component:	phosphatidylinositol 3-kinase complex plasma membrane cytoplasm
PANTHER protein class:	kinase

Pathway Categories:

VEGF signaling pathway

Phosphatidylinositol 3-kinase

Ras Pathway

Phosphatidylinositol 3-kinase

Hypoxia response via HIF activation

Phosphatidylinositol 3-kinase

Insulin/IGF pathway-protein kinase B signaling cascade

Phosphatidylinositol 3-kinase

Inflammation mediated by chemokine and cytokine signaling pathway

Phosphatidylinositol 3-kinase

FGF signaling pathway

Phosphatidylinositol 3-kinase

Angiogenesis

Phosphatidylinositol 3-kinase

EGF receptor signaling pathway

Phosphatidylinositol 3-kinase

Integrin signalling pathway

Phosphatidylinositol 3-kinase

Axon guidance mediated by netrin

Phosphatidylinositol 3-kinase

PDGF signaling pathway

Phosphatidylinositol 3-kinase

Endothelin signaling pathway

Phosphatidylinositol 3-kinase

p53 pathway feedback loops 2

Phosphatidylinositol 3-kinase

Apoptosis signaling pathway

Phosphatidylinositol 3-kinase

p53 pathway

Phosphatidylinositol 3-kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, adenylate cyclase activator activity, protein kinase activator activity, small GTPase binding, adenylate cyclase inhibitor activity, 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity, kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, 1-phosphatidylinositol-3-kinase activity
GO BP Complete:	negative chemotaxis, regulation of cell morphogenesis, positive regulation of macropinocytosis, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol phosphate biosynthetic process, response to cAMP, phosphatidylinositol biosynthetic process, chemotaxis to cAMP, chemotaxis, phosphatidylinositol 3-kinase/protein kinase B signal transduction, phagolysosome assembly, cell migration, bleb assembly, G protein-coupled receptor signaling pathway, aggregation involved in sorocarp development, phagosome maturation, regulation of ruffle assembly, cell motility, response to bacterium, macropinocytosis, phosphatidylinositol-mediated signaling, maintenance of cell polarity, response to caffeine, regulation of chemotaxis, actin cytoskeleton organization, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, asexual reproduction, pseudopodium assembly
GO CC Complete:	cytoplasm, cell leading edge, cytosol, pseudopodium, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Hemostasis, Metabolism, Clathrin-mediated endocytosis, Signaling by GPCR, Synthesis of PIPs at the plasma membrane, GPVI-mediated activation cascade, Vesicle-mediated transport, Signal Transduction, Synthesis of PIPs at the Golgi membrane, Membrane Trafficking, Platelet activation, signaling and aggregation, Metabolism of lipids, Synthesis of PIPs at the early endosome membrane, Synthesis of PIPs at the late endosome membrane, Phospholipid metabolism, GPCR downstream signalling, PI Metabolism, G beta:gamma signalling through PI3Kgamma, G-protein beta:gamma signalling

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8978\|UniProtKB=P48736	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019573.6\|UniProtKB=A0A2J8QY32	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014735.3\|UniProtKB=G3S7D1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011385.3\|UniProtKB=F6W7C8	Macaca mulatta	O
MOUSE\|MGI=MGI=1353576\|UniProtKB=Q9JHG7	Mus musculus	O
RAT\|RGD=1306468\|UniProtKB=D3ZFJ0	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020848.6\|UniProtKB=A0A3Q1M2L5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027272.3\|UniProtKB=I3LJB7	Sus scrofa	O
PIG\|Gene=PIK3CG\|UniProtKB=O02697	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019708.4\|UniProtKB=F7DD93	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004554.6\|UniProtKB=M3W2E5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026701.1\|UniProtKB=A0A8I3S601	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016386.4\|UniProtKB=F7E9G2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049478.1\|UniProtKB=A0A6I8PK17	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010009050.1\|UniProtKB=A0A8V0XVL2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014783.3\|UniProtKB=G1KQF3	Anolis carolinensis	O
XENLA\|Gene=LOC108711184\|UniProtKB=A0A8J1MN31	Xenopus laevis	O
XENLA\|Gene=pik3cg.S\|UniProtKB=A0A1L8GTX9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1011009\|UniProtKB=A0A8J0S934	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000001750.2\|UniProtKB=H2L8L2	Oryzias latipes	O
DANRE\|Gene=si=rp71-17i16.5\|UniProtKB=A0A8M9Q3P0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013171.1\|UniProtKB=W5N6H2	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000009458.2\|UniProtKB=H2M0C9	Oryzias latipes	O
DANRE\|Gene=pik3cg\|UniProtKB=A0A8M9Q5U7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015829.1\|UniProtKB=W5NFS7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006921.3\|UniProtKB=F6VP00	Ciona intestinalis	O
ANOCA\|Ensembl=ENSACAG00000011632.4\|UniProtKB=H9GIG2	Anolis carolinensis	O
DANRE\|ZFIN=ZDB-GENE-070112-492\|UniProtKB=A0A8M2BHX1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013570.1\|UniProtKB=W5N7Y0	lepisosteus oculatus	O
HUMAN\|HGNC=8975\|UniProtKB=P42336	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015642.4\|UniProtKB=A0A2I3T7A8	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009365.3\|UniProtKB=G3R1S6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000005188.4\|UniProtKB=H9FVU5	Macaca mulatta	O
MOUSE\|MGI=MGI=1206581\|UniProtKB=P42337	Mus musculus	O
RAT\|RGD=620916\|UniProtKB=A0A0G2K344	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009232\|UniProtKB=P32871	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000030413.4\|UniProtKB=A0A5K1UB41	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015019.4\|UniProtKB=F6VFI8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000018737.5\|UniProtKB=A0A2I2UYM7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015587.1\|UniProtKB=A0A5F4C2B1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000021305.5\|UniProtKB=F7G3I5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013922.3\|UniProtKB=F7DUD6	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010018296.1\|UniProtKB=O42391	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004872.4\|UniProtKB=G1KDE7	Anolis carolinensis	O
XENLA\|Gene=pik3ca.L\|UniProtKB=A0A8J1KR78	Xenopus laevis	O
XENLA\|Gene=pik3ca.S\|UniProtKB=A0A1L8G3Z7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-998106\|UniProtKB=B0BLW6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000011644.2\|UniProtKB=H2LYJ3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000008938.2\|UniProtKB=H2LYJ4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-130409-1\|UniProtKB=F1QAD7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001119.1\|UniProtKB=W5LYS0	lepisosteus oculatus	O
BRAFL\|Gene=LOC118430400\|UniProtKB=A0A9J7MA80	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC754280\|UniProtKB=A0A7M7SZL6	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000090\|UniProtKB=Q94125	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG02868\|UniProtKB=P0C5E7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00108058\|UniProtKB=A0A2A6CZC4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277220\|UniProtKB=A0A2A6CYZ1	Pristionchus pacificus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_333863\|UniProtKB=E9HU18	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_300912\|UniProtKB=E9HFD3	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG155850\|UniProtKB=T1ELN4	helobdella robusta	O
HUMAN\|HGNC=8976\|UniProtKB=P42338	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000009579.3\|UniProtKB=G3R2C2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008666.4\|UniProtKB=F7F3S0	Macaca mulatta	O
MOUSE\|MGI=MGI=1922019\|UniProtKB=Q8BTI9	Mus musculus	O
RAT\|RGD=620917\|UniProtKB=Q9Z1L0	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000006909.6\|UniProtKB=F1MYM3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000021203.4\|UniProtKB=A0A8X9AEI7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000023941.4\|UniProtKB=F6X8V3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000002828.6\|UniProtKB=M3VZ77	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025921.1\|UniProtKB=A0A8I3PWT3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000018581.4\|UniProtKB=A0A5F8GWH0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014698.4\|UniProtKB=F7GAP5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010025125.1\|UniProtKB=Q5F4A2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002884.4\|UniProtKB=G1KBQ4	Anolis carolinensis	O
XENLA\|Gene=pik3cb.L\|UniProtKB=A0A1L8GB27	Xenopus laevis	O
XENLA\|Gene=pik3cb.S\|UniProtKB=A0A1L8G4U9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-482674\|UniProtKB=Q0IHS8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015529.2\|UniProtKB=A0A3B3HRG4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-1904\|UniProtKB=E7F251	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004421.1\|UniProtKB=W5MA77	lepisosteus oculatus	O
HUMAN\|HGNC=8977\|UniProtKB=O00329	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000000120.7\|UniProtKB=K7BKN5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000012386.3\|UniProtKB=A0A2I2ZMF3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006224.4\|UniProtKB=H9ZA48	Macaca mulatta	O
MOUSE\|MGI=MGI=1098211\|UniProtKB=O35904	Mus musculus	O
RAT\|RGD=1310990\|UniProtKB=A0A8I5Y949	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000018984.5\|UniProtKB=E1BE66	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000003395.6\|UniProtKB=A0A5K1UPW2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006847.4\|UniProtKB=F7DHK6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000026305.4\|UniProtKB=M3XAA6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845028970.1\|UniProtKB=A0A8I3Q525	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003005.4\|UniProtKB=F6Q3H7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008173.4\|UniProtKB=F7EMH6	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010017035.1\|UniProtKB=F1NHX1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013317.4\|UniProtKB=H9GJU9	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000005422.2\|UniProtKB=A0A3B3IIX4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1128\|UniProtKB=Q7SYE7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006919.1\|UniProtKB=W5MJ15	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000005192.3\|UniProtKB=F7B6Z2	Ciona intestinalis	O
BRAFL\|Gene=LOC118430307\|UniProtKB=A0A9J7M9W5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC588097\|UniProtKB=A0A7M7P1G8	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0015279\|UniProtKB=P91634	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000018\|UniProtKB=A0A1S4G8E1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC011996\|UniProtKB=D6X2N9	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_117886\|UniProtKB=E9HU25	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG96068\|UniProtKB=T1G9A0	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g242402\|UniProtKB=A7S2J3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG26293\|UniProtKB=B3RZJ1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_7145\|UniProtKB=A9UW25	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_18656\|UniProtKB=A9UWS0	Monosiga brevicollis	O
HUMAN\|HGNC=8971\|UniProtKB=O00443	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003399.5\|UniProtKB=H2Q383	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011040.3\|UniProtKB=G3RRS8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022548.4\|UniProtKB=F6Y9J9	Macaca mulatta	O
MOUSE\|MGI=MGI=1203729\|UniProtKB=Q61194	Mus musculus	O
RAT\|RGD=1310389\|UniProtKB=D3ZTF6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004901.6\|UniProtKB=E1BE68	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000025406.3\|UniProtKB=I3LLX2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014963.4\|UniProtKB=F6U9E2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000023161.4\|UniProtKB=A0A2I2UT47	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027085.1\|UniProtKB=A0A8I3SAR3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000007062.5\|UniProtKB=F6PV08	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007685.3\|UniProtKB=F6VDD2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023209.1\|UniProtKB=A0A8V0ZLS9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000045.4\|UniProtKB=G1K875	Anolis carolinensis	O
XENLA\|Gene=pik3c2a.S\|UniProtKB=A0A1L8GEH2	Xenopus laevis	O
XENLA\|Gene=pik3c2a.L\|UniProtKB=A0A1L8GIB5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-484563\|UniProtKB=F6SUB4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000001292.2\|UniProtKB=A0A3B3IHY8	Oryzias latipes	O
DANRE\|Gene=pik3c2a\|UniProtKB=A0A8M2B5U1	Danio rerio	O
DANRE\|Ensembl=ENSDARG00000109612.1\|UniProtKB=A0A2R8QSP1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002963.1\|UniProtKB=W5M537	lepisosteus oculatus	O
HUMAN\|HGNC=8973\|UniProtKB=O75747	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004741.5\|UniProtKB=A0A2J8QPU6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000017159.3\|UniProtKB=G3RLT6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022174.4\|UniProtKB=F6XHZ4	Macaca mulatta	O
MOUSE\|MGI=MGI=1203730\|UniProtKB=O70167	Mus musculus	O
RAT\|RGD=620231\|UniProtKB=O70173	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020715.6\|UniProtKB=E1B8D1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000591.5\|UniProtKB=A0A5K1VBK6	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000000247.6\|UniProtKB=M3VUD0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018749.1\|UniProtKB=A0A8I3NWP1	Canis lupus familiaris	O
CHICK\|Ensembl=ENSGALG00010013617.1\|UniProtKB=A0A8V0YN62	Gallus gallus	O
XENLA\|Gene=LOC108712508\|UniProtKB=A0A1L8GQ56	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000045201\|UniProtKB=A0A803KDN3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000029595.1\|UniProtKB=A0A3B3H7C6	Oryzias latipes	O
DANRE\|Gene=pik3c2g\|UniProtKB=A0A8M6Z287	Danio rerio	O
HUMAN\|HGNC=8972\|UniProtKB=O00750	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001888.6\|UniProtKB=K7D8P6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001355.3\|UniProtKB=G3QG89	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016563.4\|UniProtKB=H9ESL7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2685045\|UniProtKB=E9QAN8	Mus musculus	LDO
RAT\|RGD=1306541\|UniProtKB=A0A0G2K1Q0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000024633.6\|UniProtKB=F1MBU9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015283.5\|UniProtKB=F1S374	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015106.4\|UniProtKB=A0A3Q2ILC5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014850.6\|UniProtKB=M3WLG8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023047.1\|UniProtKB=A0A8I3PM55	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001583.4\|UniProtKB=F7BBM1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013462.3\|UniProtKB=F7FB55	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027372.1\|UniProtKB=A0A1D5PQ64	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007419.3\|UniProtKB=G1KGS9	Anolis carolinensis	LDO
XENTR\|Gene=pik3c2b\|UniProtKB=A0A8J1J4B3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010776.2\|UniProtKB=H2M4Z3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050309-145\|UniProtKB=F1QWN6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012102.1\|UniProtKB=W5N2P3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023383.1\|UniProtKB=H2Y1I5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414477\|UniProtKB=A0A9J7L1K4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586734\|UniProtKB=A0A7M7P313	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00009552\|UniProtKB=G5EDY0	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG07670\|UniProtKB=A8X4B6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00095713\|UniProtKB=A0A2A6BJJ3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0015278\|UniProtKB=Q7K3H0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011036\|UniProtKB=A0A1S4H5J3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC034925\|UniProtKB=A0A139WAA5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303261\|UniProtKB=E9FU84	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW004026\|UniProtKB=B7PIF4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022811\|UniProtKB=B7QET6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g90881\|UniProtKB=A7RRA6	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28086\|UniProtKB=A9V757	Monosiga brevicollis	LDO
ENTH1\|EnsemblGenome=EHI_188970\|UniProtKB=C4M2W4	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_006130\|UniProtKB=C4M2P7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_095130\|UniProtKB=C4M4S6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_040690\|UniProtKB=C4M5P0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_009890\|UniProtKB=C4M0Q4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_013980\|UniProtKB=C4LXN9	Entamoeba histolytica	O
DICPU\|EnsemblGenome=DICPUDRAFT_58194\|UniProtKB=F0ZZM8	Dictyostelium purpureum	LDO
GIAIC\|EnsemblGenome=GL50803_14855\|UniProtKB=A8B5J3	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_393100\|UniProtKB=A2DYA6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_344900\|UniProtKB=A2F0T8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_083340\|UniProtKB=A2DM61	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_284350\|UniProtKB=A2EN93	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_101460\|UniProtKB=A2DJM8	Trichomonas vaginalis	LDO
PARTE\|EnsemblGenome=GSPATT00018694001\|UniProtKB=A0DN72	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00019938001\|UniProtKB=A0DT78	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012877001\|UniProtKB=A0D2V1	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00027505001\|UniProtKB=A0EIN5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039649001\|UniProtKB=A0DLV0	Paramecium tetraurelia	O
PHYRM\|Gene=H3GL97_PHYRM\|UniProtKB=H3GL97	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GLA1_PHYRM\|UniProtKB=H3GLA1	Phytophthora ramorum	O
KLENI\|Gene_ORFName=KFL_003910060\|UniProtKB=A0A1Y1IAN1	Klebsormidium nitens	LDO