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Gene Symbol(s):
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Fgf1
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Fibroblast growth factor 1
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| Gene ID: |
MGI:95515
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| Protein ID: |
P61148
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| Persistent Id: |
PTN000160313 |
| Alternate Ids: |
| FGF1_MOUSE(UniProtKB-ID) |
MGI:95515(MGI) |
| NP_034327(refSeq) |
P10935(AltAccession) |
| ENSMUSG00000036585(Ensembl) |
755560527(GI) |
| U36457(EMBL) |
AAC52969(EMBL-CDS) |
| Fgf1(Symbol) |
ENSMUST00000115582(Ensembl_TRS) |
| ENSMUSP00000157968(Ensembl_PRO) |
Fgf-1(Synonym) |
14164(GeneID) |
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Show All
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| GO MF Complete: |
growth factor activity, protein binding, integrin binding, heparin binding, S100 protein binding, fibroblast growth factor receptor binding, Hsp70 protein binding
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| GO BP Complete: |
positive regulation of MAP kinase activity, positive regulation of cell population proliferation, branch elongation involved in ureteric bud branching, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of cholesterol biosynthetic process, positive regulation of intracellular signal transduction, positive regulation of transcription by RNA polymerase II, positive regulation of angiogenesis, wound healing, mesonephric epithelium development, cellular response to heat, epithelial cell proliferation, positive regulation of cell division, angiogenesis, positive regulation of DNA-templated transcription, positive regulation of endothelial cell migration, positive regulation of epithelial cell proliferation, activation of protein kinase B activity, lung development, positive regulation of sprouting angiogenesis, positive regulation of MAPK cascade, vasculogenesis involved in coronary vascular morphogenesis, cardiac muscle cell proliferation, regulation of endothelial tube morphogenesis, positive regulation of protein phosphorylation, positive regulation of ERK1 and ERK2 cascade, organ induction, regulation of endothelial cell chemotaxis to fibroblast growth factor, regulation of cell migration, positive regulation of hepatocyte proliferation, positive regulation of cell migration
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| GO CC Complete: |
nucleus, extracellular space, cytoplasm, cell cortex, cytosol, extracellular matrix, extracellular region, nucleoplasm
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| Reactome Pathways: |
Signaling by Receptor Tyrosine Kinases, PI-3K cascade:FGFR2, PIP3 activates AKT signaling, FRS-mediated FGFR1 signaling, RAF/MAP kinase cascade, SHC-mediated cascade:FGFR1, Signaling by Insulin receptor, PI-3K cascade:FGFR4, Downstream signaling of activated FGFR1, Insulin receptor signalling cascade, PI-3K cascade:FGFR1, Negative regulation of FGFR2 signaling, Negative regulation of FGFR1 signaling, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Signal Transduction, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, PI-3K cascade:FGFR3, FRS-mediated FGFR4 signaling, Downstream signaling of activated FGFR4, MAPK family signaling cascades, SHC-mediated cascade:FGFR4, FGFR2 ligand binding and activation, FGFR1 ligand binding and activation, Negative regulation of the PI3K/AKT network, FGFR4 ligand binding and activation, IRS-related events triggered by IGF1R, IGF1R signaling cascade, Signaling by FGFR4, Signaling by FGFR3, Phospholipase C-mediated cascade; FGFR4, FRS-mediated FGFR2 signaling, Phospholipase C-mediated cascade; FGFR3, MAPK1/MAPK3 signaling, FGFR3 ligand binding and activation, FRS-mediated FGFR3 signaling, Signaling by FGFR, SHC-mediated cascade:FGFR3, IRS-mediated signalling, Downstream signaling of activated FGFR3, FGFR1c ligand binding and activation, FGFR3b ligand binding and activation, FGFR3c ligand binding and activation, FGFR2b ligand binding and activation, FGFR2c ligand binding and activation, Intracellular signaling by second messengers, PI3K Cascade, FGFR1b ligand binding and activation, Phospholipase C-mediated cascade; FGFR2, Negative regulation of FGFR3 signaling, SHC-mediated cascade:FGFR2, Downstream signaling of activated FGFR2, Signaling by FGFR1, Phospholipase C-mediated cascade: FGFR1, Negative regulation of FGFR4 signaling, Signaling by FGFR2
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