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Gene Symbol(s):
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Fgf1
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| Organism: |
Rattus norvegicus |
| View Gene in Tree |
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| Gene Name: |
Fibroblast growth factor 1
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| Gene ID: |
2605
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| Protein ID: |
P61149
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| Persistent Id: |
PTN000160314 |
| Alternate Ids: |
| 2605(RGD) |
HBGF-1(Synonym) |
| 25317(GeneID) |
ENSRNOP00000070685(Ensembl_PRO) |
| P10935(AltAccession) |
FGF1_RAT(UniProtKB-ID) |
| 134104606(GI) |
XP_006254713(refSeq) |
| X14232(EMBL) |
ENSRNOG00000013867(Ensembl) |
| ENSRNOT00000087408(Ensembl_TRS) |
CAA32448(EMBL-CDS) |
Fgf1(Symbol) |
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Show All
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| GO MF Complete: |
growth factor activity, integrin binding, heparin binding, S100 protein binding, fibroblast growth factor receptor binding, Hsp70 protein binding
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| GO BP Complete: |
positive regulation of MAP kinase activity, positive regulation of cell population proliferation, branch elongation involved in ureteric bud branching, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of cholesterol biosynthetic process, positive regulation of intracellular signal transduction, positive regulation of transcription by RNA polymerase II, positive regulation of angiogenesis, wound healing, mesonephric epithelium development, cellular response to heat, epithelial cell proliferation, positive regulation of cell division, angiogenesis, positive regulation of endothelial cell migration, positive regulation of epithelial cell proliferation, activation of protein kinase B activity, lung development, positive regulation of sprouting angiogenesis, positive regulation of MAPK cascade, regulation of endothelial tube morphogenesis, positive regulation of protein phosphorylation, positive regulation of ERK1 and ERK2 cascade, organ induction, regulation of endothelial cell chemotaxis to fibroblast growth factor, regulation of cell migration, positive regulation of hepatocyte proliferation, positive regulation of cell migration
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| GO CC Complete: |
nucleus, extracellular space, cytoplasm, cell cortex, cytosol, extracellular matrix, extracellular region, nucleoplasm
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| Reactome Pathways: |
Signaling by Insulin receptor, Insulin receptor signalling cascade, Downstream signaling of activated FGFR3, FRS-mediated FGFR3 signaling, IRS-related events triggered by IGF1R, FRS-mediated FGFR2 signaling, Phospholipase C-mediated cascade; FGFR3, Phospholipase C-mediated cascade; FGFR4, Signaling by FGFR4, SHC-mediated cascade:FGFR3, FGFR3 ligand binding and activation, Signaling by FGFR, SHC-mediated cascade:FGFR4, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Negative regulation of the PI3K/AKT network, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), FRS-mediated FGFR4 signaling, FGFR2 ligand binding and activation, PI-3K cascade:FGFR3, FGFR1 ligand binding and activation, Downstream signaling of activated FGFR4, FRS-mediated FGFR1 signaling, IRS-mediated signalling, Downstream signaling of activated FGFR2, MAPK family signaling cascades, FGFR4 ligand binding and activation, PI-3K cascade:FGFR2, PIP3 activates AKT signaling, PI-3K cascade:FGFR1, Signaling by Receptor Tyrosine Kinases, FGFR2c ligand binding and activation, PI-3K cascade:FGFR4, PI3K Cascade, Downstream signaling of activated FGFR1, SHC-mediated cascade:FGFR1, FGFR1c ligand binding and activation, Negative regulation of FGFR1 signaling, FGFR3c ligand binding and activation, FGFR3b ligand binding and activation, Negative regulation of FGFR2 signaling, FGFR1b ligand binding and activation, MAPK1/MAPK3 signaling, Signaling by FGFR3, Phospholipase C-mediated cascade; FGFR2, FGFR2b ligand binding and activation, Signal Transduction, RAF/MAP kinase cascade, IGF1R signaling cascade, Negative regulation of FGFR4 signaling, Intracellular signaling by second messengers, Negative regulation of FGFR3 signaling, SHC-mediated cascade:FGFR2, Signaling by FGFR2, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1
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