PANTHER Gene Information   
Gene Symbol(s): PRKCQ
Organism: Homo sapiens
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Gene Name: Protein kinase C theta type
Gene ID: HGNC:9410
Protein ID: Q04759
Enhancers: View enhancers for HUMAN|HGNC=9410|UniProtKB=Q04759
Genetic Variant Annotation: Annoq
Persistent Id: PTN002519425
Alternate Ids:
171848702(GI) CHEMBL3920(ChEMBL)
XP_016871900(refSeq) 2.7.11.13 {ECO:0000269|PubMed:23509302, ECO:0000269|PubMed:34593629}(EC)
600448(MIM) HGNC:9410(HGNC)
AL137145(EMBL) KPCT(Synonym)
5588(GeneID) KPCT_HUMAN(UniProtKB-ID)
PRKCQ(Symbol) Q9H549(AltAccession)
AAA75571(EMBL-CDS) ENSG00000065675(Ensembl)
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PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: PROTEIN KINASE C THETA TYPE (PTHR24356:SF181)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Histamine H1 receptor mediated signaling pathway
   Protein kinase C
Apoptosis signaling pathway
   Protein kinase C
T cell activation
   Protein kinase C, theta
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   Protein kinase C
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Protein kinase C
Oxytocin receptor mediated signaling pathway
   Protein kinase C
Wnt signaling pathway
   Protein Kinase C
FGF signaling pathway
   Protein kinase C
Thyrotropin-releasing hormone receptor signaling pathway
   Protein kinase C
Angiogenesis
   Protein kinase B
Gonadotropin-releasing hormone receptor pathway
   PKCe/theta
Endothelin signaling pathway
   protein kinase c
VEGF signaling pathway
   Protein kinase C
Alzheimer disease-amyloid secretase pathway
   Protein kinase C
EGF receptor signaling pathway
   PKC
CCKR signaling map
   PKCtheta
5HT2 type receptor mediated signaling pathway
   Protein kinase C
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, protein binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity, protein serine kinase activity, diacylglycerol-dependent serine/threonine kinase activity
GO BP Complete: positive regulation of T-helper 2 cell activation, Fc-epsilon receptor signaling pathway, regulation of DNA-templated transcription, axon guidance, regulation of platelet aggregation, protein phosphorylation, negative regulation of insulin receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, cell chemotaxis, positive regulation of T-helper 17 type immune response, inflammatory response, positive regulation of T cell activation, membrane protein ectodomain proteolysis, regulation of cell growth, CD4-positive, alpha-beta T cell proliferation, negative regulation of T cell apoptotic process, positive regulation of interleukin-17 production, positive regulation of telomere maintenance, positive regulation of interleukin-4 production, intracellular signal transduction, positive regulation of CD4-positive, alpha-beta T cell proliferation, positive regulation of interleukin-2 production
GO CC Complete: centriolar satellite, cytosol, aggresome, plasma membrane, immunological synapse
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Fc epsilon receptor (FCERI) signaling, MAPK family signaling cascades, Sensory Perception, RNA Polymerase II Transcription, Apoptotic cleavage of cellular proteins, Platelet activation, signaling and aggregation, Signaling by GPCR, Transcriptional regulation by RUNX1, TCR signaling, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function, Signal Transduction, Innate Immune System, Downstream TCR signaling, G alpha (q) signalling events, Hemostasis, Apoptosis, G alpha (z) signalling events, RAS processing, Developmental Biology, RAF/MAP kinase cascade, MAPK1/MAPK3 signaling, GPCR downstream signalling, FCERI mediated NF-kB activation, Effects of PIP2 hydrolysis, Generic Transcription Pathway, Visual phototransduction, Netrin-1 signaling, Immune System, Gene expression (Transcription), Apoptotic execution phase, Adaptive Immune System, Programmed Cell Death, Inactivation, recovery and regulation of the phototransduction cascade, Axon guidance, Nervous system development, The phototransduction cascade

Orthologs