PANTHER Gene Information   
Gene Symbol(s): GNAI3
Organism: Bos taurus
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Gene Name: G protein subunit alpha i3
Gene ID: ENSBTAG00000013016.4
Protein ID: Q3ZCA7
Persistent Id: PTN000026642
Alternate Ids:
BC102645(EMBL) ABQ12937(EMBL-CDS)
Q3ZCA7(Synonym) ENSBTAT00000017303(Ensembl_TRS)
77736299(GI) NP_001029849(refSeq)
Q3ZCA7_BOVIN(UniProtKB-ID) ENSBTAG00000013016(Ensembl)
ENSBTAP00000017303(Ensembl_PRO) 539521(GeneID)
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PANTHER Classification
PANTHER Family: GTP-BINDING PROTEIN ALPHA SUBUNIT (PTHR10218)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 (PTHR10218:SF230)  
PANTHER GO-slim Molecular Function: GTPase activity
G protein-coupled receptor binding
protein-containing complex binding
PANTHER GO-slim Biological Process: adenylate cyclase-modulating G protein-coupled receptor signaling pathway
dopamine receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Gi-protein, alpha subunit
5HT1 type receptor mediated signaling pathway
   G-protein
Endogenous cannabinoid signaling
   Gi/o-protein, alpha subunit
Enkephalin release
   Gi-protein
Inflammation mediated by chemokine and cytokine signaling pathway
   Gi/q-protein, alpha subunit
Opioid proenkephalin pathway
   G-protein
Opioid prodynorphin pathway
   G-protein
PI3 kinase pathway
   G-protein, alpha subunit
Gonadotropin-releasing hormone receptor pathway
   gnai
Inflammation mediated by chemokine and cytokine signaling pathway
   Gi-protein, alpha subunit
Dopamine receptor mediated signaling pathway
   Gi-protein, alpha subunit
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Nicotine pharmacodynamics pathway
   Guanine nuceotide-binding protein, alpha-inhibiting activity polypeptide
Metabotropic glutamate receptor group III pathway
   Gi-protein
Metabotropic glutamate receptor group II pathway
   G-protein
GABA-B receptor II signaling
   G-protein (i/o), alpha subunit

GO MF Complete: G protein-coupled receptor binding, GTPase activity, G-protein beta/gamma-subunit complex binding
GO BP Complete: G protein-coupled dopamine receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO CC Complete: heterotrimeric G-protein complex, cytoplasm
Reactome Pathways: Signaling by Nuclear Receptors, Adenylate cyclase inhibitory pathway, G alpha (i) signalling events, Platelet activation, signaling and aggregation, Signal Transduction, Signal amplification, GPCR downstream signalling, Hemostasis, Signaling by GPCR, ESR-mediated signaling, Extra-nuclear estrogen signaling, GABA B receptor activation, ADP signalling through P2Y purinoceptor 12, Opioid Signalling, Transmission across Chemical Synapses, GABA receptor activation, Neuronal System, Neurotransmitter receptors and postsynaptic signal transmission, G-protein mediated events, Activation of GABAB receptors