PANTHER Gene Information   
Gene Symbol(s): gnai3
Organism: Xenopus tropicalis
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Gene Name: G protein subunit alpha i3
Gene ID: XB-GENE-5738634
Protein ID: Q5I080
Persistent Id: PTN000026667
Alternate Ids:
82179266(GI) NM_001011471(refSeq)
CAJ82808(EMBL-CDS) BC088604(EMBL)
Q5I080_XENTR(UniProtKB-ID) ENSXETG00000002003(Ensembl)
ENSXETT00000004295(Ensembl_TRS) ENSXETP00000004295(Ensembl_PRO)
496962(GeneID) Q5I080(Synonym)
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PANTHER Classification
PANTHER Family: GTP-BINDING PROTEIN ALPHA SUBUNIT (PTHR10218)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 (PTHR10218:SF230)  
PANTHER GO-slim Molecular Function: GTPase activity
G protein-coupled receptor binding
protein-containing complex binding
PANTHER GO-slim Biological Process: adenylate cyclase-modulating G protein-coupled receptor signaling pathway
dopamine receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Gi-protein, alpha subunit
5HT1 type receptor mediated signaling pathway
   G-protein
Endogenous cannabinoid signaling
   Gi/o-protein, alpha subunit
Enkephalin release
   Gi-protein
Inflammation mediated by chemokine and cytokine signaling pathway
   Gi/q-protein, alpha subunit
Opioid proenkephalin pathway
   G-protein
Opioid prodynorphin pathway
   G-protein
PI3 kinase pathway
   G-protein, alpha subunit
Gonadotropin-releasing hormone receptor pathway
   gnai
Inflammation mediated by chemokine and cytokine signaling pathway
   Gi-protein, alpha subunit
Dopamine receptor mediated signaling pathway
   Gi-protein, alpha subunit
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Nicotine pharmacodynamics pathway
   Guanine nuceotide-binding protein, alpha-inhibiting activity polypeptide
Metabotropic glutamate receptor group III pathway
   Gi-protein
Metabotropic glutamate receptor group II pathway
   G-protein
GABA-B receptor II signaling
   G-protein (i/o), alpha subunit

GO MF Complete: GTP binding, G protein-coupled receptor binding, GTPase activity, G-protein beta/gamma-subunit complex binding
GO BP Complete: signal transduction, G protein-coupled dopamine receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO CC Complete: heterotrimeric G-protein complex, cytoplasm
Reactome Pathways: Signal Transduction, G-protein mediated events, Hemostasis, GABA B receptor activation, GABA receptor activation, G alpha (i) signalling events, Signal amplification, ESR-mediated signaling, Extra-nuclear estrogen signaling, GPCR downstream signalling, Neuronal System, Adenylate cyclase inhibitory pathway, Activation of GABAB receptors, ADP signalling through P2Y purinoceptor 12, Transmission across Chemical Synapses, Signaling by Nuclear Receptors, Neurotransmitter receptors and postsynaptic signal transmission, Opioid Signalling, Platelet activation, signaling and aggregation, Signaling by GPCR