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Gene Symbol(s):
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Pik3r2
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| Organism: |
Rattus norvegicus |
| View Gene in Tree |
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| Gene Name: |
Phosphatidylinositol 3-kinase regulatory subunit beta
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| Gene ID: |
68341
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| Protein ID: |
Q63788
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| Persistent Id: |
PTN000016406 |
| Alternate Ids: |
| D64046(EMBL) |
1246390(GI) |
| 68341(RGD) |
PI3-kinase subunit p85-beta(Synonym) |
| Pik3r2(Symbol) |
P85B_RAT(UniProtKB-ID) |
BAA10926(EMBL-CDS) |
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Show All
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| GO MF Complete: |
phosphotyrosine residue binding, protein phosphatase binding, phosphatidylinositol 3-kinase regulatory subunit binding, protein heterodimerization activity, kinase activity, receptor tyrosine kinase binding, 1-phosphatidylinositol-3-kinase regulator activity
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| GO BP Complete: |
regulation of protein localization to plasma membrane, positive regulation of protein import into nucleus, insulin receptor signaling pathway, negative regulation of MAPK cascade, protein transport, regulation of stress fiber assembly, positive regulation of cell adhesion, positive regulation of transcription by RNA polymerase II, negative regulation of cell migration involved in sprouting angiogenesis, regulation of actin filament polymerization, cellular response to insulin stimulus, phosphatidylinositol 3-kinase/protein kinase B signal transduction, intracellular glucose homeostasis, regulation of autophagy, response to endoplasmic reticulum stress
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| GO CC Complete: |
phosphatidylinositol 3-kinase complex, class IA, nucleus, focal adhesion, cytosol
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| Reactome Pathways: |
Phospholipid metabolism, DAP12 signaling, Downstream signal transduction, Signaling by SCF-KIT, Cell surface interactions at the vascular wall, Signaling by Insulin receptor, Insulin receptor signalling cascade, ESR-mediated signaling, Extra-nuclear estrogen signaling, Fcgamma receptor (FCGR) dependent phagocytosis, RHO GTPase cycle, Costimulation by the CD28 family, RHOJ GTPase cycle, RHOA GTPase cycle, Role of phospholipids in phagocytosis, RHOD GTPase cycle, RAC2 GTPase cycle, IRS-related events triggered by IGF1R, G alpha (q) signalling events, RHOF GTPase cycle, Role of LAT2/NTAL/LAB on calcium mobilization, Developmental Biology, Signaling by PDGF, Interleukin-7 signaling, GPVI-mediated activation cascade, Signaling by ALK, TCR signaling, Nervous system development, Signaling by Rho GTPases, Signaling by NTRKs, RND3 GTPase cycle, PI3K/AKT activation, RND2 GTPase cycle, RET signaling, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, RND1 GTPase cycle, Negative regulation of the PI3K/AKT network, GPCR downstream signalling, Immune System, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Adaptive Immune System, Cytokine Signaling in Immune system, Signaling by GPCR, IRS-mediated signalling, Fc epsilon receptor (FCERI) signaling, MAPK family signaling cascades, VEGFA-VEGFR2 Pathway, Signaling by NTRK1 (TRKA), Hemostasis, Interleukin receptor SHC signaling, PIP3 activates AKT signaling, CD28 dependent PI3K/Akt signaling, Interleukin-3, Interleukin-5 and GM-CSF signaling, Signaling by Interleukins, CD28 co-stimulation, Signaling by Nuclear Receptors, RAC1 GTPase cycle, Platelet activation, signaling and aggregation, Signaling by VEGF, Signaling by Receptor Tyrosine Kinases, RHOU GTPase cycle, Innate Immune System, CDC42 GTPase cycle, PI3K Cascade, RHOB GTPase cycle, DAP12 interactions, MAPK1/MAPK3 signaling, Signal Transduction, Downstream TCR signaling, RAF/MAP kinase cascade, IGF1R signaling cascade, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Synthesis of PIPs at the plasma membrane, Interleukin-2 family signaling, Axon guidance, Metabolism, Regulation of signaling by CBL, Metabolism of lipids, Intracellular signaling by second messengers, Tie2 Signaling, PI Metabolism
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