PANTHER Gene Information   
Gene Symbol(s): gnai2
Organism: Danio rerio
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Gene Name: Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Gene ID: ZDB-GENE-030131-5861
Protein ID: Q7ZWI5
Persistent Id: PTN002230879
Alternate Ids:
ENSDARG00000017294(Ensembl) 41054141(GI)
BC049343(EMBL) AAH49343(EMBL-CDS)
Q7ZWI5_DANRE(UniProtKB-ID) NP_956136(refSeq)
ZDB-GENE-030131-5861(ZFIN) 327650(GeneID)
ENSDART00000079694(Ensembl_TRS) ENSDARP00000074146(Ensembl_PRO)
Q7ZWI5(Synonym)
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PANTHER Classification
PANTHER Family: GTP-BINDING PROTEIN ALPHA SUBUNIT (PTHR10218)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 (PTHR10218:SF73)  
PANTHER GO-slim Molecular Function: GTPase activity
G protein-coupled receptor binding
protein-containing complex binding
PANTHER GO-slim Biological Process: cell-cell signaling
cell surface receptor signaling pathway
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Gi-protein, alpha subunit
5HT1 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Opioid prodynorphin pathway
   G-protein
PI3 kinase pathway
   G-protein, alpha subunit
Gonadotropin-releasing hormone receptor pathway
   gnai
Inflammation mediated by chemokine and cytokine signaling pathway
   Gi-protein, alpha subunit
Opioid proopiomelanocortin pathway
   G-protein
Dopamine receptor mediated signaling pathway
   Gi-protein, alpha subunit
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Metabotropic glutamate receptor group II pathway
   G-protein

GO MF Complete: nucleotide binding, GTP binding, G protein-coupled receptor binding, GTPase activity, guanyl nucleotide binding, G-protein beta/gamma-subunit complex binding
GO BP Complete: adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, G protein-coupled adenosine receptor signaling pathway, G protein-coupled receptor signaling pathway, signal transduction, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, gamma-aminobutyric acid signaling pathway
GO CC Complete: centrosome, heterotrimeric G-protein complex, cytoplasm
Reactome Pathways: Signaling by Nuclear Receptors, Activation of GABAB receptors, Adrenaline,noradrenaline inhibits insulin secretion, Signaling by GPCR, GPCR downstream signalling, Hemostasis, Integration of energy metabolism, Signal Transduction, Neurotransmitter receptors and postsynaptic signal transmission, Opioid Signalling, Transmission across Chemical Synapses, Neuronal System, Signal amplification, Platelet activation, signaling and aggregation, ESR-mediated signaling, Extra-nuclear estrogen signaling, G-protein mediated events, Regulation of insulin secretion, Adenylate cyclase inhibitory pathway, GABA B receptor activation, ADP signalling through P2Y purinoceptor 12, G alpha (i) signalling events, GABA receptor activation, Metabolism