PANTHER Gene Information   
Gene Symbol(s): HDAC7
Organism: Homo sapiens
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Gene Name: Histone deacetylase 7
Gene ID: HGNC:14067
Protein ID: Q8WUI4
Enhancers: View enhancers for HUMAN|HGNC=14067|UniProtKB=Q8WUI4
Genetic Variant Annotation: Annoq
Persistent Id: PTN002472083
Alternate Ids:
HDAC7_HUMAN(UniProtKB-ID) 471270359(GI)
XP_011536783(refSeq) Q96K01(AltAccession)
BAB55363(EMBL-CDS) ENSG00000061273(Ensembl)
HDAC7(Synonym) AC004466(EMBL)
606542(MIM) CHEMBL2716(ChEMBL)
51564(GeneID) HGNC:14067(HGNC)
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PANTHER Classification
PANTHER Family: HISTONE DEACETYLASE HDAC1-RELATED (PTHR10625)
PANTHER Subfamily: HISTONE DEACETYLASE 7 (PTHR10625:SF42)  
PANTHER GO-slim Molecular Function: histone deacetylase activity
PANTHER GO-slim Biological Process: epigenetic regulation of gene expression
PANTHER GO-slim Cellular Component: histone deacetylase complex
PANTHER protein class:
Pathway Categories: CCKR signaling map
   HDAC7

GO MF Complete: protein kinase C binding, protein kinase binding, tubulin deacetylase activity, chromatin binding, histone H3K4 deacetylase activity, hydrolytic mechanism, histone H4K8 deacetylase activity, hydrolytic mechanism, histone H4K16 deacetylase activity, hydrolytic mechanism, histone H4K5 deacetylase activity, hydrolytic mechanism, histone H4K12 deacetylase activity, hydrolytic mechanism, protein binding, histone deacetylase activity, transcription corepressor activity, metal ion binding, histone H3K14 deacetylase activity, hydrolytic mechanism, histone H3K9 deacetylase activity, hydrolytic mechanism, protein lysine deacetylase activity, DNA-binding transcription factor binding, SUMO transferase activity, 14-3-3 protein binding
GO BP Complete: negative regulation of transcription by RNA polymerase II, negative regulation of interleukin-2 production, regulation of mRNA processing, cell-cell junction assembly, protein sumoylation, protein deacetylation, negative regulation of non-canonical NF-kappaB signal transduction, vasculogenesis, chromatin organization, positive regulation of cell migration involved in sprouting angiogenesis, epigenetic regulation of gene expression, negative regulation of osteoblast differentiation
GO CC Complete: nucleus, cytoplasm, histone deacetylase complex, cytosol, nucleoplasm
Reactome Pathways: Metabolism of proteins, Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer, Generic Transcription Pathway, RNA Polymerase II Transcription, Disease, PTEN Regulation, Post-translational protein modification, Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants, Notch-HLH transcription pathway, Signaling by NOTCH, Diseases of signal transduction by growth factor receptors and second messengers, Signal Transduction, PIP3 activates AKT signaling, Signaling by NOTCH1, SUMOylation, Gene expression (Transcription), Regulation of PTEN gene transcription, Signaling by NOTCH1 in Cancer, Signaling by NOTCH1 PEST Domain Mutants in Cancer, SUMO E3 ligases SUMOylate target proteins, Constitutive Signaling by NOTCH1 PEST Domain Mutants, NOTCH1 Intracellular Domain Regulates Transcription, SUMOylation of DNA damage response and repair proteins, Intracellular signaling by second messengers