PANTHER Gene Information

Gene Symbol(s):

KCNJ9

Organism:

Homo sapiens

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Gene Name:

G protein-activated inward rectifier potassium channel 3

Gene ID:

HGNC:6270

Protein ID:

Q92806

Enhancers:

View enhancers for HUMAN|HGNC=6270|UniProtKB=Q92806

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002482936

Alternate Ids:

ENSG00000162728(Ensembl)	AAB07043(EMBL-CDS)
125987834(GI)	KCNJ9_HUMAN(UniProtKB-ID)
Q5JW75(AltAccession)	AF193615(EMBL)
HGNC:6270(HGNC)	3765(GeneID)
600932(MIM)	ENSP00000357067(Ensembl_PRO)
Potassium channel, inwardly rectifying subfamily J member 9(Synonym)	CHEMBL3038490(ChEMBL)
ENST00000368088(Ensembl_TRS)	KCNJ9(Symbol)
NM_004983(refSeq)
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PANTHER Classification

PANTHER Family:	INWARD RECTIFIER POTASSIUM CHANNEL (PTHR11767)
PANTHER Subfamily:	G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 (PTHR11767:SF17)
PANTHER GO-slim Molecular Function:	voltage-gated potassium channel activity ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process:	potassium ion import across plasma membrane regulation of monoatomic ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ion channel

Pathway Categories:

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

G-protein receptor kinase

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

G protein-coupled inwardly rectifying potassium channel

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

G protein-activated inward rectifying potassium channel

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	G-protein activated inward rectifier potassium channel activity, protein binding, inward rectifier potassium channel activity
GO BP Complete:	potassium ion import across plasma membrane, regulation of monoatomic ion transmembrane transport, regulation of presynaptic membrane potential
GO CC Complete:	presynaptic membrane, parallel fiber to Purkinje cell synapse, monoatomic ion channel complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

GABA receptor activation, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, GABA B receptor activation, Potassium Channels, Activation of G protein gated Potassium channels, Activation of GABAB receptors, Neuronal System, Inwardly rectifying K+ channels, Neurotransmitter receptors and postsynaptic signal transmission, Transmission across Chemical Synapses, G protein gated Potassium channels

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000001538.3\|UniProtKB=H2Q0D9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000025489.2\|UniProtKB=G3RTV2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000054510.1\|UniProtKB=A0A5F7ZS69	Macaca mulatta	LDO
MOUSE\|MGI=MGI=108007\|UniProtKB=P48543	Mus musculus	LDO
RAT\|RGD=621440\|UniProtKB=Q63511	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000024507.4\|UniProtKB=A0A3Q1MHN1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006393.5\|UniProtKB=A0A5G2R5J2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000030879.2\|UniProtKB=A0A9L0TJ44	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015120.6\|UniProtKB=A0A2I2UIL2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030853.1\|UniProtKB=A0A8I3QQ27	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009988.3\|UniProtKB=A0A5F8HDP0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000039350.1\|UniProtKB=A0A6I8N768	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000016136.4\|UniProtKB=H9GMX9	Anolis carolinensis	LDO
XENLA\|Gene=LOC108700451\|UniProtKB=A0A8J1LN08	Xenopus laevis	O
XENLA\|Gene=kcnj9.L\|UniProtKB=A0A1L8FDH3	Xenopus laevis	LDO
XENTR\|Gene=LOC100489771\|UniProtKB=A0A8J1ITT1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002457.2\|UniProtKB=H2LAY4	Oryzias latipes	LDO
DANRE\|Gene=kcnj9\|UniProtKB=A0A8M3AQ22	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000000922.1\|UniProtKB=W5LY22	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023776.1\|UniProtKB=F6XQI0	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_121818\|UniProtKB=C3YD60	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426070\|UniProtKB=A0A9J7N316	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC584140\|UniProtKB=A0A7M7NLD4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918598\|UniProtKB=A0A7M7NRA6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584158\|UniProtKB=A0A7M7NRN0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592565\|UniProtKB=A0A7M7LSG3	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00002151\|UniProtKB=A0A1C3NSK2	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10649\|UniProtKB=A8XBI7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096471\|UniProtKB=A0A2A6B4B2	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00002149\|UniProtKB=P52192	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10884\|UniProtKB=A8XC74	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00002150\|UniProtKB=A0A1C3NSN6	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08126\|UniProtKB=A8X5V6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00203627\|UniProtKB=A0A2A6CGW5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032706\|UniProtKB=B7YZX2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007818\|UniProtKB=A0A1S4GX11	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP028144\|UniProtKB=A0A1S4HEA1	Anopheles gambiae	O
DROME\|FlyBase=FBgn0039081\|UniProtKB=A0A0B4LHI9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001283\|UniProtKB=Q7PX91	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP001284\|UniProtKB=Q7PKL0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP001281\|UniProtKB=Q7PKK8	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC034483\|UniProtKB=A0A139WBX6	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC006707\|UniProtKB=D6WYJ8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033608\|UniProtKB=A0A139WFH2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC006708\|UniProtKB=D6WYJ9	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001199\|UniProtKB=D6WAQ3	Tribolium castaneum	O
DROME\|FlyBase=FBgn0265042\|UniProtKB=A0A0B4KH86	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029806\|UniProtKB=A0A499FWX7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006706\|UniProtKB=D6WYJ7	Tribolium castaneum	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_42289\|UniProtKB=E9FXS2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_311738\|UniProtKB=E9FXS0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW016219\|UniProtKB=B7P0N6	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG107917\|UniProtKB=T1EED8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG157415\|UniProtKB=T1EMB1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG179553\|UniProtKB=T1FEV3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122541\|UniProtKB=T1EGU9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG79786\|UniProtKB=T1G3T3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG73033\|UniProtKB=T1G190	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG108208\|UniProtKB=T1EEG9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82781\|UniProtKB=T1G4W5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122071\|UniProtKB=T1EGT8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82544\|UniProtKB=T1G4T5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122255\|UniProtKB=T1EGU3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG106279\|UniProtKB=T1EE13	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g52170\|UniProtKB=A7SE20	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g170615\|UniProtKB=A7SH65	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101684\|UniProtKB=A7S217	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93919\|UniProtKB=A7RUM3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG3835\|UniProtKB=B3RMY4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25718\|UniProtKB=A9V082	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_24696\|UniProtKB=A9UX72	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_32445\|UniProtKB=A9UZJ5	Monosiga brevicollis	O
LEIMA\|EnsemblGenome=LMJF_09_0480\|UniProtKB=Q4QHX6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.4330\|UniProtKB=Q382T2	Trypanosoma brucei	O
THAPS\|EnsemblGenome=THAPS_25330\|UniProtKB=B5YLJ0	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_24946\|UniProtKB=B8CCX1	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_21089\|UniProtKB=B8BSL6	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_5256\|UniProtKB=B8C2E6	Thalassiosira pseudonana	O
PHYRM\|Gene=H3HCM1_PHYRM\|UniProtKB=H3HCM1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_01g035800v5\|UniProtKB=A0A2K3E712	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g311650v5\|UniProtKB=A0A2K3DRT3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g591450v5\|UniProtKB=A0A2K3D141	Chlamydomonas reinhardtii	O
PHYPA\|EnsemblGenome=Pp3c15_3810\|UniProtKB=A0A7I3Z5Z2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_4440\|UniProtKB=A0A2K1K204	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0015s0176\|UniProtKB=A0A2R6XH25	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_005570020\|UniProtKB=A0A1Y1II39	Klebsormidium nitens	O