PANTHER Gene Information   
Gene Symbol(s): Dll4
Organism: Mus musculus
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Gene Name: Delta-like protein 4
Gene ID: MGI:1859388
Protein ID: Q9JI71
Persistent Id: PTN000621452
Alternate Ids:
DLL4(Synonym) AK004739(EMBL)
Q9DBU9(AltAccession) DLL4_MOUSE(UniProtKB-ID)
NP_062327(refSeq) 12836139(GI)
ENSMUSG00000027314(Ensembl) BAB18580(EMBL-CDS)
54485(GeneID) MGI:1859388(MGI)
Dll4(Symbol) ENSMUSP00000099575(Ensembl_PRO)
ENSMUST00000102517(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: NOTCH LIGAND FAMILY MEMBER (PTHR24044)
PANTHER Subfamily: DELTA-LIKE PROTEIN 4 (PTHR24044:SF320)  
PANTHER GO-slim Molecular Function: signaling receptor binding
PANTHER GO-slim Biological Process: negative regulation of Notch signaling pathway
Notch signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane
PANTHER protein class: intercellular signal molecule
Pathway Categories: Angiogenesis
   Delta
Notch signaling pathway
   Delta
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein binding, calcium ion binding, Notch binding, receptor ligand activity
GO BP Complete: regulation of neural retina development, negative regulation of cell population proliferation, negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis, negative regulation of Notch signaling pathway, positive regulation of Notch signaling pathway, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of transcription by RNA polymerase II, angiogenesis, branching involved in blood vessel morphogenesis, cardiac ventricle morphogenesis, cardiac atrium morphogenesis, positive regulation of neural precursor cell proliferation, dorsal aorta morphogenesis, negative regulation of endothelial cell migration, negative regulation of blood vessel endothelial cell migration, aortic valve morphogenesis, cellular response to fibroblast growth factor stimulus, visual perception, ventricular trabecula myocardium morphogenesis, pericardium morphogenesis, ventral spinal cord interneuron fate commitment, T cell differentiation, negative regulation of gene expression, blood vessel remodeling, Notch signaling pathway, blood vessel lumenization, positive regulation of gene expression, cellular response to vascular endothelial growth factor stimulus, regulation of neurogenesis
GO CC Complete: plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signal Transduction, NOTCH3 Activation and Transmission of Signal to the Nucleus, Signaling by NOTCH3, Signaling by NOTCH

Orthologs