PANTHER Class Information 
| Name: | THO complex |
| Definition: | The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. |
| Class ID: | GO:0000347 |
| Parent Lineages: |
cellular_component>
cellular anatomical entity>
organelle>
membrane-bounded organelle>
intracellular membrane-bounded organelle>
nucleus>
nuclear protein-containing complex>
THO complex
cellular_component> cellular anatomical entity> organelle> intracellular organelle> intracellular membrane-bounded organelle> nucleus> nuclear protein-containing complex> THO complex cellular_component> cellular anatomical entity> intracellular anatomical structure> intracellular organelle> intracellular membrane-bounded organelle> nucleus> nuclear protein-containing complex> THO complex cellular_component> protein-containing complex> nuclear protein-containing complex> THO complex |
| Child: | |
| Number Subfamilies/Families: | 20 |
