Name: | cytoplasmic dynein complex |
Definition: | Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains. |
Class ID: | GO:0005868 |
Parent Lineages: |
cellular_component>
protein-containing complex>
catalytic complex>
dynein complex>
cytoplasmic dynein complex
cellular_component> cellular anatomical entity> organelle> non-membrane-bounded organelle> intracellular non-membrane-bounded organelle> cytoskeleton> microtubule cytoskeleton> microtubule associated complex> dynein complex> cytoplasmic dynein complex cellular_component> cellular anatomical entity> organelle> intracellular organelle> intracellular non-membrane-bounded organelle> cytoskeleton> microtubule cytoskeleton> microtubule associated complex> dynein complex> cytoplasmic dynein complex cellular_component> cellular anatomical entity> intracellular anatomical structure> intracellular organelle> intracellular non-membrane-bounded organelle> cytoskeleton> microtubule cytoskeleton> microtubule associated complex> dynein complex> cytoplasmic dynein complex cellular_component> protein-containing complex> microtubule associated complex> dynein complex> cytoplasmic dynein complex |
Child: | |
Number Subfamilies/Families: | 79 |