PANTHER Class Information

Name:	nucleotide-excision repair
Definition:	A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
Class ID:	GO:0006289
Parent Lineages:	biological_process> metabolic process> organic substance metabolic process> macromolecule metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> metabolic process> nitrogen compound metabolic process> cellular nitrogen compound metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> metabolic process> cellular metabolic process> cellular nitrogen compound metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> cellular process> cellular metabolic process> cellular nitrogen compound metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> metabolic process> cellular metabolic process> heterocycle metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> cellular process> cellular metabolic process> heterocycle metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> metabolic process> cellular metabolic process> cellular aromatic compound metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> cellular process> cellular metabolic process> cellular aromatic compound metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> metabolic process> organic substance metabolic process> organic cyclic compound metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> metabolic process> primary metabolic process> nucleobase-containing compound metabolic process> nucleic acid metabolic process> DNA metabolic process> DNA repair> nucleotide-excision repair biological_process> response to stimulus> cellular response to stimulus> cellular response to stress> DNA damage response> DNA repair> nucleotide-excision repair biological_process> cellular process> cellular response to stimulus> cellular response to stress> DNA damage response> DNA repair> nucleotide-excision repair biological_process> response to stimulus> response to stress> cellular response to stress> DNA damage response> DNA repair> nucleotide-excision repair
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Number Subfamilies/Families:	138