PANTHER Class Information 
| Name: | G protein-coupled receptor signaling pathway |
| Definition: | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| Class ID: | GO:0007186 |
| Parent Lineages: |
biological_process>
biological regulation>
regulation of biological process>
regulation of cellular process>
signal transduction>
G protein-coupled receptor signaling pathway
biological_process> cellular process> cell communication> signal transduction> G protein-coupled receptor signaling pathway biological_process> cellular process> signal transduction> G protein-coupled receptor signaling pathway biological_process> biological regulation> regulation of biological process> signaling> signal transduction> G protein-coupled receptor signaling pathway biological_process> response to stimulus> cellular response to stimulus> signal transduction> G protein-coupled receptor signaling pathway biological_process> cellular process> cellular response to stimulus> signal transduction> G protein-coupled receptor signaling pathway |
| Child: |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway neuropeptide signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway |
| Number Subfamilies/Families: | 1235 |
