Name: | CCR4-NOT complex |
Definition: | The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8. |
Class ID: | GO:0030014 |
Parent Lineages: |
cellular_component>
protein-containing complex>
intracellular protein-containing complex>
CCR4-NOT complex
|
Child: | |
Number Subfamilies/Families: | 103 |