PANTHER Class Information

Name:	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Definition:	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
Class ID:	GO:0042771
Parent Lineages:	biological_process> response to stimulus> cellular response to stimulus> cellular response to stress> DNA damage response> intrinsic apoptotic signaling pathway in response to DNA damage> intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological_process> cellular process> cellular response to stimulus> cellular response to stress> DNA damage response> intrinsic apoptotic signaling pathway in response to DNA damage> intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological_process> response to stimulus> response to stress> cellular response to stress> DNA damage response> intrinsic apoptotic signaling pathway in response to DNA damage> intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological_process> biological regulation> regulation of biological process> regulation of cellular process> signal transduction> intracellular signal transduction> intrinsic 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Number Subfamilies/Families:	8