PANTHER Pathway  >   EGF receptor signaling pathway >   Cas-Br-M (murine) ecotropic retroviral transforming oncogene

Pathway Component Details   
Name: Cas-Br-M (murine) ecotropic retroviral transforming oncogene (c-Cbl)
Definition: c-Cbl is an ubiquitin ligase that induces the degradation of EGFR
Category ID: P00544
Synonyms:
Upstream:
Downstream: epidermal growth factor receptor  (EGFR)
Number Families/Subfamilies: 4
Number of Associated Sequences: 19
GO Molecular Function: -
GO Biological Process: -
GO Cellular Component: -
PANTHER protein class: -
References: Medline:14523545 

Sequence Association
Panther Subfamily Associated Sequence Definition Confidence Code Evidence
PTHR23007:SF11 Q19019 E3 ubiquitin-protein ligase CBL ISS  
  Q9VSK2 E3 ubiquitin-protein ligase CBL ISS  
PTHR23007:SF12 Q80XL1 E3 ubiquitin-protein ligase CBL-C ISS 12845517  
  Q9ULV8 E3 ubiquitin-protein ligase CBL-C IGI PubMed:99289203  
PTHR23007:SF3 A0A3Q1LUB2 E3 ubiquitin-protein ligase CBL ISS PubMed:95303504  
  A0A5F8ACF3 E3 ubiquitin-protein ligase CBL ISS PubMed:95303504  
  A0A8I3PCV8 E3 ubiquitin-protein ligase CBL ISS PubMed:95303504  
  H2QN18 E3 ubiquitin-protein ligase CBL ISS PubMed:95303504  
  Q13191 E3 ubiquitin-protein ligase CBL-B IGI PubMed:95303504  
  Q3TTA7 E3 ubiquitin-protein ligase CBL-B ISS PubMed:95303504  
  Q8K4S7 E3 ubiquitin-protein ligase CBL-B ISS PubMed:95303504  
PTHR23007:SF5 A0A1D5RFE7 E3 ubiquitin-protein ligase CBL ISS 4885117  
  A0A1D5RFE7 E3 ubiquitin-protein ligase CBL ISS 6680858  
  A0A3Q1LN00 E3 ubiquitin-protein ligase CBL ISS 4885117  
  A0A8I3MBU4 E3 ubiquitin-protein ligase CBL ISS 4885117  
  A0A8I6G3R2 E3 ubiquitin-protein ligase CBL ISS 4885117  
  A0A8I6G3R2 E3 ubiquitin-protein ligase CBL ISS 6680858  
  H2Q4Y2 E3 ubiquitin-protein ligase CBL ISS 4885117  
  H2Q4Y2 E3 ubiquitin-protein ligase CBL ISS 6680858  
  P22681 E3 ubiquitin-protein ligase CBL IGI 4885117  
  P22682 E3 ubiquitin-protein ligase CBL IGI 6680858  
  Q5U376 E3 ubiquitin-protein ligase CBL ISS