PANTHER Gene Information

Gene Symbol(s):

POLB

Organism:

Bos taurus

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Gene Name:

DNA polymerase beta

Gene ID:

ENSBTAG00000000225

Protein ID:

Q27958

Persistent Id:

PTN007500937

Alternate Ids:

ENSBTAP00000000276(Ensembl_PRO)	S80341(EMBL)
614688(GeneID)	Q3ZBL6(AltAccession)
ENSBTAT00000000276(Ensembl_TRS)	2494199(GI)
POLB(Symbol)	DPOLB_BOVIN(UniProtKB-ID)
NP_001029936(refSeq)	DPOLB(Synonym)
ENSBTAG00000000225(Ensembl)	4.2.99.18 {ECO:0000250\|UniProtKB:P06746}(EC)
AAD14333(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	DNA POLYMERASE TYPE-X FAMILY MEMBER (PTHR11276)
PANTHER Subfamily:	DNA POLYMERASE BETA (PTHR11276:SF42)
PANTHER GO-slim Molecular Function:	DNA-directed DNA polymerase activity
PANTHER GO-slim Biological Process:	base-excision repair double-strand break repair via nonhomologous end joining
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	DNA-directed DNA polymerase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, DNA-directed DNA polymerase activity, metal ion binding, lyase activity, class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO BP Complete:	base-excision repair, DNA-templated DNA replication, DNA biosynthetic process, double-strand break repair via nonhomologous end joining, DNA damage response
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Ub-specific processing proteases, Post-translational protein modification, Metabolism of proteins, APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway, PCNA-Dependent Long Patch Base Excision Repair, Deubiquitination, Resolution of Abasic Sites (AP sites), Abasic sugar-phosphate removal via the single-nucleotide replacement pathway, Base Excision Repair, DNA Repair, Resolution of AP sites via the multiple-nucleotide patch replacement pathway, POLB-Dependent Long Patch Base Excision Repair, Resolution of AP sites via the single-nucleotide replacement pathway

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9174\|UniProtKB=P06746	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020203.4\|UniProtKB=H2QW35	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009239.3\|UniProtKB=G3SIQ7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000065244.1\|UniProtKB=I0FSR3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97740\|UniProtKB=Q8K409	Mus musculus	LDO
RAT\|RGD=3363\|UniProtKB=P06766	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000007031.5\|UniProtKB=A0A286ZNU0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000035919.3\|UniProtKB=A0A9L0S1Y4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022846.4\|UniProtKB=M3XC91	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845006104.1\|UniProtKB=A0A8I3NDB6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010196.2\|UniProtKB=F6STA6	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010018030.1\|UniProtKB=A0A8V0ZBR9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001998.3\|UniProtKB=H9G5Y0	Anolis carolinensis	LDO
XENLA\|Gene=polb.S\|UniProtKB=A0A8J0UU72	Xenopus laevis	O
XENLA\|Gene=polb\|UniProtKB=O57383	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-999698\|UniProtKB=F7A2G2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002509.2\|UniProtKB=H2LB48	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040830-1\|UniProtKB=Q6DRD3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015620.1\|UniProtKB=W5NF22	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000022190.1\|UniProtKB=H2XPD1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118411507\|UniProtKB=A0A9J7MJF8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582628\|UniProtKB=A0A7M7GHH1	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC033458\|UniProtKB=A0A139WG05	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW024905\|UniProtKB=B7QKW0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG184959\|UniProtKB=T1FM74	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g171103\|UniProtKB=A7SJ46	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50243\|UniProtKB=B3RW50	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_33482\|UniProtKB=A9V5M0	Monosiga brevicollis	LDO
YEAST\|SGD=S000000607\|UniProtKB=P25615	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL039W\|UniProtKB=Q757Q1	Eremothecium gossypii	LDO
CRYNJ\|EnsemblGenome=CNA04063\|UniProtKB=A0A0S2LHY9	Cryptococcus neoformans	LDO
CRYNJ\|EnsemblGenome=CNL05040\|UniProtKB=Q5K8N6	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_01262\|UniProtKB=A0A0D1CE68	Ustilago maydis	LDO
DICDI\|dictyBase=DDB_G0284713\|UniProtKB=Q1ZXF2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_33968\|UniProtKB=F0ZLU7	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_08_0890\|UniProtKB=Q4QI80	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.5.2780\|UniProtKB=D6XGL4	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_08_0900\|UniProtKB=Q4QI79	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.160.2480\|UniProtKB=Q38FE5	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.5.2790\|UniProtKB=Q57ZV5	Trypanosoma brucei	O
PARTE\|EnsemblGenome=GSPATT00012937001\|UniProtKB=A0D335	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027758001\|UniProtKB=A0BDW1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015723001\|UniProtKB=A0DCU7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008489001\|UniProtKB=A0CMJ3	Paramecium tetraurelia	O
PHYRM\|Gene=H3GBE1_PHYRM\|UniProtKB=H3GBE1	Phytophthora ramorum	O
PHYRM\|Gene=H3GCI4_PHYRM\|UniProtKB=H3GCI4	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_01g013000v5\|UniProtKB=A0A2K3E5N7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g716101v5\|UniProtKB=A0A2K3CPZ5	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g176300v5\|UniProtKB=A0A2K3DXG3	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00088p00121830\|UniProtKB=W1NW65	Amborella trichopoda	O
MUSAM\|EnsemblGenome=Ma03_g10070\|UniProtKB=A0A804IAF7	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_006186mg\|UniProtKB=K3XW78	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G097500\|UniProtKB=A0A194YIA1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb371940\|UniProtKB=K7V573	Zea mays	O
ORYSJ\|Gene_OrderedLocusName=LOC_Os06g13020\|UniProtKB=Q67VC8	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g44820v3\|UniProtKB=I1GZF6	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0667530\|UniProtKB=F2DD24	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7B02G098700\|UniProtKB=A0A3B6SAI7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G193400\|UniProtKB=A0A3B6RFZ7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G194700\|UniProtKB=A0A3B6TGB3	Triticum aestivum	O
NELNU\|Gene=LOC104607940\|UniProtKB=A0A1U8QAI7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110782885\|UniProtKB=A0A9R0I5D4	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0163981\|UniProtKB=A0A251S492	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900489260\|UniProtKB=A0A9R1UD39	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a026593mg\|UniProtKB=A0A022QLW0	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_27543\|UniProtKB=A0A1U8EKH6	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc05g006120.3\|UniProtKB=A0A3Q7H525	Solanum lycopersicum	O
TOBAC\|Gene=LOC107817483\|UniProtKB=A0A1S4CCE0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107793193\|UniProtKB=A0A1S4A326	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_01s0026g00650\|UniProtKB=D7TNM4	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_B02561\|UniProtKB=A0A059D505	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C08P13760.1\|UniProtKB=A0A078G277	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00015101001\|UniProtKB=A0A078G384	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C08P13780.1\|UniProtKB=A0A078G6M7	Brassica napus	O
BRACM\|EnsemblGenome=Bra018434\|UniProtKB=M4DPJ3	Brassica campestris	O
ARATH\|TAIR=locus=2194610\|UniProtKB=Q9FNY4	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107948535\|UniProtKB=A0A1U8NHM3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107901984\|UniProtKB=A0A1U8J4U5	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_010205\|UniProtKB=A0A061E7L2	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g0093031mg\|UniProtKB=A0A067H4W7	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_010G094800v3\|UniProtKB=B9HVB4	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_01G196700\|UniProtKB=A0A2C9WNL1	Manihot esculenta	O
SOYBN\|EnsemblGenome=GLYMA_02G065600\|UniProtKB=I1JCZ1	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g040170\|UniProtKB=G7KDW6	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_7g039450\|UniProtKB=A0A072TY09	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr16_10480\|UniProtKB=A0A2I4E805	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G603350\|UniProtKB=A0A0A0KQD3	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G259900\|UniProtKB=M5XMY2	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_106459\|UniProtKB=D8S132	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_83116\|UniProtKB=D8R0V4	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c15_19010\|UniProtKB=A0A7I4F590	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0057s0101\|UniProtKB=A0A2R6WUJ4	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000180140\|UniProtKB=A0A1Y1HP31	Klebsormidium nitens	O
RICCO\|Gene_ORFName=RCOM_0699970\|UniProtKB=B9S2K3	Ricinus communis	O
SELML\|EnsemblGenome=SELMODRAFT_155063\|UniProtKB=D8SG82	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_86291\|UniProtKB=D8R616	Selaginella moellendorffii	O
MARPO\|EnsemblGenome=MARPO_0078s0005\|UniProtKB=A0A2R6WL40	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_008070060\|UniProtKB=A0A1Y1IN70	Klebsormidium nitens	O
METAC\|EnsemblGenome=MA_0727\|UniProtKB=Q8TSR8	Methanosarcina acetivorans	O
STAA8\|EnsemblGenome=SAOUHSC_01098\|UniProtKB=Q2FZD4	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_28590\|UniProtKB=P94544	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4553\|UniProtKB=Q817J3	Bacillus cereus	O
RHOBA\|EnsemblGenome=RB4749\|UniProtKB=Q7UHA8	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB1485\|UniProtKB=Q7UX90	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_1422\|UniProtKB=O67416	Aquifex aeolicus	O
DICTD\|EnsemblGenome=Dtur_1600\|UniProtKB=B8E2M9	Dictyoglomus turgidum	O
COXBU\|EnsemblGenome=CBU_0490\|UniProtKB=Q83E42	Coxiella burnetii	O