PANTHER Gene Information   
Gene Symbol(s): POLB
Organism: Canis lupus familiaris
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Gene Name: DNA polymerase
Gene ID: ENSCAFG00845006104.1
Protein ID: A0A8I3NDB6
Persistent Id: PTN000138711
Alternate Ids:
A0A8I3NDB6_CANLF(UniProtKB-ID) XP_532790(refSeq)
ENSCAFP00845008457(Ensembl_PRO) A0A8I3NDB6(Synonym)
494001(GeneID) ENSCAFG00845006104(Ensembl)
73979125(GI) ENSCAFT00845010836(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: DNA POLYMERASE TYPE-X FAMILY MEMBER (PTHR11276)
PANTHER Subfamily: DNA POLYMERASE BETA (PTHR11276:SF42)  
PANTHER GO-slim Molecular Function: DNA-directed DNA polymerase activity
PANTHER GO-slim Biological Process: base-excision repair
double-strand break repair via nonhomologous end joining
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA-directed DNA polymerase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, DNA-directed DNA polymerase activity, 5'-deoxyribose-5-phosphate lyase activity, metal ion binding, class I DNA-(apurinic or apyrimidinic site) endonuclease activity, microtubule binding, enzyme binding
GO BP Complete: immunoglobulin heavy chain V-D-J recombination, base-excision repair, DNA replication, spleen development, intrinsic apoptotic signaling pathway in response to DNA damage, lymph node development, base-excision repair, gap-filling, double-strand break repair via nonhomologous end joining, salivary gland morphogenesis, inflammatory response, in utero embryonic development, homeostasis of number of cells, DNA biosynthetic process, neuron apoptotic process, somatic hypermutation of immunoglobulin genes
GO CC Complete: nucleus, spindle microtubule, cytoplasm, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism of proteins, Base Excision Repair, DNA Repair, Resolution of Abasic Sites (AP sites), Resolution of AP sites via the single-nucleotide replacement pathway, Ub-specific processing proteases, Abasic sugar-phosphate removal via the single-nucleotide replacement pathway, APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway, Post-translational protein modification, PCNA-Dependent Long Patch Base Excision Repair, Deubiquitination, Resolution of AP sites via the multiple-nucleotide patch replacement pathway, POLB-Dependent Long Patch Base Excision Repair

Orthologs