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Gene Symbol(s):
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FGF2
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| Organism: |
Bos taurus |
| View Gene in Tree |
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| Gene Name: |
Fibroblast growth factor 2
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| Gene ID: |
ENSBTAG00000005691
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| Protein ID: |
P03969
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| Persistent Id: |
PTN002608254 |
| Alternate Ids: |
| ENSBTAP00000007477(Ensembl_PRO) |
21697980(GI) |
| FGF2(Symbol) |
bFGF(Synonym) |
| AAA30518(EMBL-CDS) |
ENSBTAT00000007477(Ensembl_TRS) |
| ENSBTAG00000005691(Ensembl) |
M13440(EMBL) |
FGF2_BOVIN(UniProtKB-ID) |
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Show All
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| GO MF Complete: |
growth factor activity, integrin binding, heparin binding, fibroblast growth factor receptor binding
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| GO BP Complete: |
signal transduction, positive regulation of sprouting angiogenesis, positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, neurogenesis, animal organ development, positive regulation of MAPK cascade, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of lens fiber cell differentiation, positive regulation of blood vessel endothelial cell migration, positive regulation of angiogenesis, positive regulation of cell division, angiogenesis, branching involved in ureteric bud morphogenesis, positive regulation of protein phosphorylation, positive regulation of ERK1 and ERK2 cascade, cell differentiation, regulation of cell migration
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| GO CC Complete: |
nucleus, extracellular space, cytoplasm, extracellular region
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| Reactome Pathways: |
FGFR3c ligand binding and activation, PI3K Cascade, Intracellular signaling by second messengers, FGFR1b ligand binding and activation, Downstream signaling of activated FGFR4, Signal Transduction, SHC-mediated cascade:FGFR4, SHC-mediated cascade:FGFR1, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, PI-3K cascade:FGFR1, FGFR2 ligand binding and activation, FGFR1 ligand binding and activation, Negative regulation of the PI3K/AKT network, RAF/MAP kinase cascade, FGFR4 ligand binding and activation, PIP3 activates AKT signaling, Negative regulation of FGFR2 signaling, Negative regulation of FGFR1 signaling, Insulin receptor signalling cascade, Signaling by Insulin receptor, PI-3K cascade:FGFR2, FGFR3 ligand binding and activation, Downstream signaling of activated FGFR2, MAPK1/MAPK3 signaling, SHC-mediated cascade:FGFR2, Negative regulation of FGFR3 signaling, Negative regulation of FGFR4 signaling, Signaling by FGFR, FRS-mediated FGFR1 signaling, Non-integrin membrane-ECM interactions, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Syndecan interactions, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1, Signaling by FGFR2, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Phospholipase C-mediated cascade; FGFR2, FGFRL1 modulation of FGFR1 signaling, Signaling by FGFR3, Signaling by FGFR4, Phospholipase C-mediated cascade; FGFR4, Phospholipase C-mediated cascade; FGFR3, FRS-mediated FGFR2 signaling, IRS-related events triggered by IGF1R, IGF1R signaling cascade, Signaling by Receptor Tyrosine Kinases, SHC-mediated cascade:FGFR3, FRS-mediated FGFR3 signaling, MAPK family signaling cascades, Downstream signaling of activated FGFR3, IRS-mediated signalling, PI-3K cascade:FGFR3, FRS-mediated FGFR4 signaling, FGFR2c ligand binding and activation, FGFR1c ligand binding and activation, Extracellular matrix organization, FGFR2b ligand binding and activation
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