PANTHER Gene Information   
Gene Symbol(s): FGF2
Organism: Sus scrofa
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Gene Name: Fibroblast growth factor
Gene ID: ENSSSCG00000036213.3
Protein ID: A0A287BGK8
Persistent Id: PTN004264493
Alternate Ids:
ENSSSCG00000036213(Ensembl) ENSSSCT00000040673(Ensembl_TRS)
ENSSSCP00000055271(Ensembl_PRO) A0A287BGK8(Synonym)
A0A287BGK8_PIG(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 2 (PTHR11486:SF83)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
fibroblast growth factor receptor signaling pathway
cell differentiation
positive regulation of protein serine/threonine kinase activity
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
regulation of MAP kinase activity
PANTHER GO-slim Cellular Component: extracellular space
nucleus
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: Angiogenesis
   Fibroblast Growth Factor
FGF signaling pathway
   fibroblast growth factor
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: growth factor activity, heparin binding, fibroblast growth factor receptor binding
GO BP Complete: positive regulation of cell division, angiogenesis, positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, neurogenesis, animal organ development, positive regulation of MAPK cascade, regulation of cell migration
GO CC Complete: nucleus, extracellular space, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: SHC-mediated cascade:FGFR4, FGFR2b ligand binding and activation, Signal Transduction, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), FRS-mediated FGFR4 signaling, Signaling by FGFR, Negative regulation of FGFR4 signaling, Signaling by FGFR1, Phospholipase C-mediated cascade: FGFR1, Non-integrin membrane-ECM interactions, Downstream signaling of activated FGFR4, Signaling by FGFR2, Syndecan interactions, FGFR1b ligand binding and activation, FRS-mediated FGFR1 signaling, FGFR1c ligand binding and activation, Intracellular signaling by second messengers, MAPK1/MAPK3 signaling, PI3K Cascade, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Extracellular matrix organization, IRS-related events triggered by IGF1R, Signaling by FGFR4, SHC-mediated cascade:FGFR1, FGFR4 ligand binding and activation, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, PI-3K cascade:FGFR1, Phospholipase C-mediated cascade; FGFR4, IRS-mediated signalling, Negative regulation of FGFR1 signaling, Negative regulation of the PI3K/AKT network, MAPK family signaling cascades, FGFR2 ligand binding and activation, Signaling by Insulin receptor, FGFRL1 modulation of FGFR1 signaling, FGFR1 ligand binding and activation, Signaling by Receptor Tyrosine Kinases, Insulin receptor signalling cascade, IGF1R signaling cascade, RAF/MAP kinase cascade, PIP3 activates AKT signaling

Orthologs