PANTHER Gene Information   
Gene Symbol(s): SRF
Organism: Bos taurus
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Gene Name: Serum response factor
Gene ID: ENSBTAG00000012777.4
Protein ID: E1BJP4
Persistent Id: PTN000235396
Alternate Ids:
ENSBTAG00000012777(Ensembl) 329664766(GI)
E1BJP4(Synonym) ENSBTAP00000016981(Ensembl_PRO)
E1BJP4_BOVIN(UniProtKB-ID) ENSBTAT00000016981(Ensembl_TRS)
533039(GeneID) NP_001192945(refSeq)
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PANTHER Classification
PANTHER Family: SERUM RESPONSE FACTOR HOMOLOG (PTHR48019)
PANTHER Subfamily: SERUM RESPONSE FACTOR (PTHR48019:SF168)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: MADS box transcription factor
Pathway Categories: CCKR signaling map
   SRF
p38 MAPK pathway
   serum response factor
Interleukin signaling pathway
   Serum response factor
PDGF signaling pathway
   c-fos
Ras Pathway
   Serum response factor
Gonadotropin-releasing hormone receptor pathway
   SRF
PDGF signaling pathway
   Serum response factor

GO MF Complete: chromatin DNA binding, protein homodimerization activity, serum response element binding, RNA polymerase II-specific DNA-binding transcription factor binding, DNA-binding transcription activator activity, RNA polymerase II-specific, primary miRNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: epithelial cell-cell adhesion, positive regulation of filopodium assembly, transcription by RNA polymerase II, cell migration involved in sprouting angiogenesis, associative learning, stress fiber assembly, skin morphogenesis, face development, response to hypoxia, platelet formation, heart looping, cardiac myofibril assembly, dorsal aorta morphogenesis, mesoderm formation, long-term synaptic depression, trophectodermal cell differentiation, sarcomere organization, negative regulation of amyloid-beta clearance, positive regulation of axon extension, positive thymic T cell selection, morphogenesis of an epithelial sheet, response to hormone, epithelial structure maintenance, bicellular tight junction assembly, response to cytokine, muscle cell cellular homeostasis, positive regulation of transcription initiation by RNA polymerase II, negative regulation of miRNA transcription, cellular senescence, tangential migration from the subventricular zone to the olfactory bulb, positive regulation of miRNA transcription, positive regulation of transcription by RNA polymerase II, heart trabecula formation, establishment of skin barrier, positive regulation of smooth muscle contraction, thymus development, lung morphogenesis, neuron migration, cardiac vascular smooth muscle cell differentiation, branching involved in blood vessel morphogenesis, megakaryocyte development, platelet activation, cell-matrix adhesion, lung smooth muscle development, hematopoietic stem cell differentiation, hippocampus development, erythrocyte development, bronchus cartilage development, filopodium assembly, cardiac muscle cell myoblast differentiation, trachea cartilage development, eyelid development in camera-type eye, thyroid gland development, axon extension, regulation of cell adhesion, primitive streak formation
GO CC Complete: nucleus, cytoplasm, chromatin
Reactome Pathways: Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Signal Transduction, RHO GTPase Effectors, RHO GTPases Activate Formins, Signaling by Rho GTPases