PANTHER Gene Information

Gene Symbol(s):

UCHL5

Organism:

Bos taurus

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Gene Name:

Ubiquitin carboxyl-terminal hydrolase isozyme L5

Gene ID:

ENSBTAG00000013620

Protein ID:

Q9XSJ0

Persistent Id:

PTN000063331

Alternate Ids:

UCH-L5(Synonym)	282110(GeneID)
Q3MHN9(AltAccession)	UCHL5_BOVIN(UniProtKB-ID)
3.4.19.12(EC)	NM_174481(refSeq)
ENSBTAG00000013620(Ensembl)	76253713(GI)
UCHL5(Symbol)	AAD31533(EMBL-CDS)
AF148446(EMBL)	ENSBTAT00000018104(Ensembl_TRS)
ENSBTAP00000018104(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE (PTHR10589)
PANTHER Subfamily:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 (PTHR10589:SF16)
PANTHER GO-slim Molecular Function:	cysteine-type deubiquitinase activity
PANTHER GO-slim Biological Process:	protein deubiquitination
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	cysteine protease

Pathway Categories:

Ubiquitin proteasome pathway

26S proteasome

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	cysteine-type deubiquitinase activity, proteasome binding
GO BP Complete:	protein deubiquitination, DNA repair, regulation of chromosome organization, DNA recombination, ubiquitin-dependent protein catabolic process
GO CC Complete:	nucleus, cytoplasm, cytosol, proteasome complex, Ino80 complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Post-translational protein modification, Metabolism of proteins, UCH proteinases, Deubiquitination

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19678\|UniProtKB=Q9Y5K5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001793.6\|UniProtKB=H2Q0T5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004347.3\|UniProtKB=A0A2I2Z588	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022641.4\|UniProtKB=A0A5F7ZIS5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914848\|UniProtKB=Q9WUP7	Mus musculus	LDO
RAT\|RGD=1305414\|UniProtKB=A0A8I6GL10	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000010802.5\|UniProtKB=F1SAA9	Sus scrofa	LDO
PIG\|Ensembl=ENSSSCG00070012107\|UniProtKB=Q06AT3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012988.4\|UniProtKB=A0A5F5PYL8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000018440.5\|UniProtKB=M3WP46	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025347.1\|UniProtKB=A0A8I3PPU0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012129.4\|UniProtKB=A0A5F8GME2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002960.4\|UniProtKB=A0A6I8P6N4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012693.1\|UniProtKB=A0A8V0YGG7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008306.4\|UniProtKB=H9GDT0	Anolis carolinensis	LDO
XENLA\|Gene=uchl5.S\|UniProtKB=A0A1L8GGT8	Xenopus laevis	O
XENLA\|Gene=uchl5.L\|UniProtKB=Q0D260	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-968743\|UniProtKB=A0A7D9NKY2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012257.2\|UniProtKB=H2M9Z1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2051\|UniProtKB=Q6NWL6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007370.1\|UniProtKB=W5MKN1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000924.3\|UniProtKB=F6U019	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118420839\|UniProtKB=A0A9J7LIV4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC576462\|UniProtKB=A0A7M7PLY5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006724\|UniProtKB=Q09444	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00034125\|UniProtKB=A8XHZ7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00116811\|UniProtKB=A0A8R1YL17	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00305144\|UniProtKB=A0A8R1ZCF0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0030370\|UniProtKB=Q9VYQ3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0011327\|UniProtKB=Q9XZ61	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005540\|UniProtKB=Q7Q728	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002490\|UniProtKB=D6WHM3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_191310\|UniProtKB=E9FUJ0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000206\|UniProtKB=B7P6T3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG172351\|UniProtKB=T1F578	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG50992\|UniProtKB=B3SA37	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32982\|UniProtKB=A9V2V6	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_AGL316W\|UniProtKB=Q751S0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000184421\|UniProtKB=A0A1D8PNY8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B16698g\|UniProtKB=Q6CEC7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03453\|UniProtKB=C8VHB3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G05510\|UniProtKB=Q4WWE1	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_10966\|UniProtKB=A7F049	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12103\|UniProtKB=Q0U811	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_00927\|UniProtKB=Q5BEV3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G15920\|UniProtKB=Q4WRL2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02382\|UniProtKB=Q7S3W3	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU03704\|UniProtKB=Q1K7Z3	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07002\|UniProtKB=A7ENV3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02461\|UniProtKB=Q0V0K3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC409.06\|UniProtKB=Q9UUB6	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02341\|UniProtKB=B6K275	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND01170\|UniProtKB=Q5KIZ8	Cryptococcus neoformans	LDO
PUCGT\|EnsemblGenome=PGTG_10272\|UniProtKB=E3KKH6	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_85969\|UniProtKB=F4NTM4	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_140500\|UniProtKB=C4M3M3	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0285527\|UniProtKB=Q54N38	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_27445\|UniProtKB=F0ZA93	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_24_0420\|UniProtKB=Q4QAT9	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.2800\|UniProtKB=Q385Q4	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_1117100\|UniProtKB=Q8IIJ6	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00027304001\|UniProtKB=A0EI36	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00020562001\|UniProtKB=A0DV33	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_26398\|UniProtKB=B8CAQ2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G8Q0_PHYRM\|UniProtKB=H3G8Q0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g253300v5\|UniProtKB=A8HYD8	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00122p00131800\|UniProtKB=W1NN79	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00067p00092640\|UniProtKB=U5CZL3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_1G02330\|UniProtKB=A0A0K9PMR3	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma00_g01020\|UniProtKB=A0A804HM56	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g00010\|UniProtKB=A0A804I6R6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_002178mg\|UniProtKB=K3XJV5	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_014052mg\|UniProtKB=K3YII3	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G448200\|UniProtKB=C5WRS1	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3007G165900\|UniProtKB=C5YMV1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb175830\|UniProtKB=A0A804NPD9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb038900\|UniProtKB=A0A1D6KM34	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0180100\|UniProtKB=Q6ETK2	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g06000v3\|UniProtKB=I1HXY5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0518770\|UniProtKB=A0A287SL97	Hordeum vulgare subsp. vulgare	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0622380\|UniProtKB=A0A287UYU6	Hordeum vulgare subsp. vulgare	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0568820\|UniProtKB=F2EC53	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G176100\|UniProtKB=A0A3B6PJK1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G147800\|UniProtKB=A0A3B6NN98	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G137100\|UniProtKB=A0A3B6QCC0	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_017763mg\|UniProtKB=K3YU17	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G350100\|UniProtKB=A0A194YTD0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb259220\|UniProtKB=C0HI50	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0822200\|UniProtKB=Q6K6Z5	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g55860v3\|UniProtKB=I1IE45	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0631190\|UniProtKB=F2E474	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G444700\|UniProtKB=A0A3B6PVE8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G386100\|UniProtKB=A0A3B6QL88	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G402500\|UniProtKB=A0A3B6NX56	Triticum aestivum	LDO
NELNU\|Gene=LOC104600020\|UniProtKB=A0A1U8AGP8	Nelumbo nucifera	O
NELNU\|Gene=LOC104597736\|UniProtKB=A0A1U7ZTV4	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104610001\|UniProtKB=A0A1U8B235	Nelumbo nucifera	O
SPIOL\|Gene=LOC110786404\|UniProtKB=A0A9R0ICH2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0347161\|UniProtKB=A0A251U761	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0017101\|UniProtKB=A0A251VMI7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900461720\|UniProtKB=A0A9R1WTU0	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009722mg\|UniProtKB=A0A022RZW1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_23302\|UniProtKB=A0A1U8E1K2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400020283\|UniProtKB=M1BT38	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g018730.3\|UniProtKB=A0A3Q7IWA6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107828186\|UniProtKB=A0A1S4DBY4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi04g01763\|UniProtKB=A5AU65	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E04242\|UniProtKB=A0A059CAW0	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A07P32920.1\|UniProtKB=A0A078F749	Brassica napus	LDO
BRANA\|Gene_ORFName=DARMORV10_C06P39140.1\|UniProtKB=A0A078HNV3	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra004123\|UniProtKB=M4CIT9	Brassica campestris	LDO
ARATH\|TAIR=locus=2171312\|UniProtKB=Q9FFF2	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2018516\|UniProtKB=O04482	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107949487\|UniProtKB=A0A1U8NNJ6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951863\|UniProtKB=A0A1U8NWQ5	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_024461\|UniProtKB=A0A061EWP2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g019907mg\|UniProtKB=A0A067ER35	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G130400v3\|UniProtKB=B9H3Y8	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_017G075200v3\|UniProtKB=B9IJQ6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_15G189000\|UniProtKB=A0A2C9UIC4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1298200\|UniProtKB=B9S046	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G170500\|UniProtKB=I1LBV4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G219500\|UniProtKB=I1NIJ5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g078300\|UniProtKB=A0A072VY12	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_23520\|UniProtKB=A0A2I4G288	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_31100\|UniProtKB=A0A6P9EJ73	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G652300\|UniProtKB=A0A0A0KSX7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G335400\|UniProtKB=M5XX13	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_94540\|UniProtKB=D8RHZ4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_231325\|UniProtKB=D8REF4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c16_12470\|UniProtKB=A0A2K1J8B0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0070s0050\|UniProtKB=A0A2R6WP02	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000500440\|UniProtKB=A0A1Y1HNS5	Klebsormidium nitens	LDO