PANTHER Gene Information

Gene Symbol(s):

Uchl5

Organism:

Rattus norvegicus

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Gene Name:

Ubiquitin carboxyl-terminal hydrolase

Gene ID:

1305414

Protein ID:

A0A8I6GL10

Persistent Id:

PTN002238866

Alternate Ids:

1305414(RGD)	ENSRNOT00000098889(Ensembl_TRS)
ENSRNOP00000094138(Ensembl_PRO)	ENSRNOG00000003545(Ensembl)
564380970(GI)	A0A8I6GL10_RAT(UniProtKB-ID)
XP_006250022(refSeq)	A0A8I6GL10(Synonym)
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PANTHER Classification

PANTHER Family:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE (PTHR10589)
PANTHER Subfamily:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 (PTHR10589:SF16)
PANTHER GO-slim Molecular Function:	cysteine-type deubiquitinase activity
PANTHER GO-slim Biological Process:	protein deubiquitination
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	cysteine protease

Pathway Categories:

Ubiquitin proteasome pathway

26S proteasome

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	cysteine-type deubiquitinase activity, endopeptidase inhibitor activity, proteasome binding
GO BP Complete:	protein deubiquitination, positive regulation of DNA repair, biological_process, regulation of proteasomal protein catabolic process, regulation of chromosome organization, regulation of DNA strand elongation, regulation of DNA repair, regulation of embryonic development, telomere maintenance, regulation of DNA replication, forebrain morphogenesis, positive regulation of telomere maintenance in response to DNA damage, ubiquitin-dependent protein catabolic process, chromatin remodeling, lateral ventricle development, midbrain development, positive regulation of DNA-templated transcription, positive regulation of smoothened signaling pathway, regulation of cell cycle, negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO CC Complete:	nucleus, cytoplasm, cytosol, cytosolic proteasome complex, Ino80 complex, nucleolus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19678\|UniProtKB=Q9Y5K5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001793.6\|UniProtKB=H2Q0T5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004347.3\|UniProtKB=A0A2I2Z588	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022641.4\|UniProtKB=A0A5F7ZIS5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914848\|UniProtKB=Q9WUP7	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000013620\|UniProtKB=Q9XSJ0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010802.5\|UniProtKB=F1SAA9	Sus scrofa	LDO
PIG\|Ensembl=ENSSSCG00070012107\|UniProtKB=Q06AT3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012988.4\|UniProtKB=A0A5F5PYL8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000018440.5\|UniProtKB=M3WP46	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025347.1\|UniProtKB=A0A8I3PPU0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012129.4\|UniProtKB=A0A5F8GME2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002960.4\|UniProtKB=A0A6I8P6N4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012693.1\|UniProtKB=A0A8V0YGG7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008306.4\|UniProtKB=H9GDT0	Anolis carolinensis	LDO
XENLA\|Gene=uchl5.S\|UniProtKB=A0A1L8GGT8	Xenopus laevis	O
XENLA\|Gene=uchl5.L\|UniProtKB=Q0D260	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-968743\|UniProtKB=A0A7D9NKY2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012257.2\|UniProtKB=H2M9Z1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2051\|UniProtKB=Q6NWL6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007370.1\|UniProtKB=W5MKN1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000924.3\|UniProtKB=F6U019	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118420839\|UniProtKB=A0A9J7LIV4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC576462\|UniProtKB=A0A7M7PLY5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006724\|UniProtKB=Q09444	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00034125\|UniProtKB=A8XHZ7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00116811\|UniProtKB=A0A8R1YL17	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00305144\|UniProtKB=A0A8R1ZCF0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0030370\|UniProtKB=Q9VYQ3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0011327\|UniProtKB=Q9XZ61	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005540\|UniProtKB=Q7Q728	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002490\|UniProtKB=D6WHM3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_191310\|UniProtKB=E9FUJ0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000206\|UniProtKB=B7P6T3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG172351\|UniProtKB=T1F578	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG50992\|UniProtKB=B3SA37	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32982\|UniProtKB=A9V2V6	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_AGL316W\|UniProtKB=Q751S0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000184421\|UniProtKB=A0A1D8PNY8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B16698g\|UniProtKB=Q6CEC7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03453\|UniProtKB=C8VHB3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G05510\|UniProtKB=Q4WWE1	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_10966\|UniProtKB=A7F049	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12103\|UniProtKB=Q0U811	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_00927\|UniProtKB=Q5BEV3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G15920\|UniProtKB=Q4WRL2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02382\|UniProtKB=Q7S3W3	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU03704\|UniProtKB=Q1K7Z3	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07002\|UniProtKB=A7ENV3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02461\|UniProtKB=Q0V0K3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC409.06\|UniProtKB=Q9UUB6	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02341\|UniProtKB=B6K275	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND01170\|UniProtKB=Q5KIZ8	Cryptococcus neoformans	LDO
PUCGT\|EnsemblGenome=PGTG_10272\|UniProtKB=E3KKH6	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_85969\|UniProtKB=F4NTM4	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_140500\|UniProtKB=C4M3M3	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0285527\|UniProtKB=Q54N38	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_27445\|UniProtKB=F0ZA93	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_24_0420\|UniProtKB=Q4QAT9	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.2800\|UniProtKB=Q385Q4	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_1117100\|UniProtKB=Q8IIJ6	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00027304001\|UniProtKB=A0EI36	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00020562001\|UniProtKB=A0DV33	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_26398\|UniProtKB=B8CAQ2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G8Q0_PHYRM\|UniProtKB=H3G8Q0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g253300v5\|UniProtKB=A8HYD8	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00122p00131800\|UniProtKB=W1NN79	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00067p00092640\|UniProtKB=U5CZL3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_1G02330\|UniProtKB=A0A0K9PMR3	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma00_g01020\|UniProtKB=A0A804HM56	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g00010\|UniProtKB=A0A804I6R6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_002178mg\|UniProtKB=K3XJV5	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_014052mg\|UniProtKB=K3YII3	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G448200\|UniProtKB=C5WRS1	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3007G165900\|UniProtKB=C5YMV1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb175830\|UniProtKB=A0A804NPD9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb038900\|UniProtKB=A0A1D6KM34	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0180100\|UniProtKB=Q6ETK2	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g06000v3\|UniProtKB=I1HXY5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0518770\|UniProtKB=A0A287SL97	Hordeum vulgare subsp. vulgare	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0622380\|UniProtKB=A0A287UYU6	Hordeum vulgare subsp. vulgare	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0568820\|UniProtKB=F2EC53	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G176100\|UniProtKB=A0A3B6PJK1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G147800\|UniProtKB=A0A3B6NN98	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G137100\|UniProtKB=A0A3B6QCC0	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_017763mg\|UniProtKB=K3YU17	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G350100\|UniProtKB=A0A194YTD0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb259220\|UniProtKB=C0HI50	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0822200\|UniProtKB=Q6K6Z5	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g55860v3\|UniProtKB=I1IE45	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0631190\|UniProtKB=F2E474	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G444700\|UniProtKB=A0A3B6PVE8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G386100\|UniProtKB=A0A3B6QL88	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G402500\|UniProtKB=A0A3B6NX56	Triticum aestivum	LDO
NELNU\|Gene=LOC104600020\|UniProtKB=A0A1U8AGP8	Nelumbo nucifera	O
NELNU\|Gene=LOC104597736\|UniProtKB=A0A1U7ZTV4	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104610001\|UniProtKB=A0A1U8B235	Nelumbo nucifera	O
SPIOL\|Gene=LOC110786404\|UniProtKB=A0A9R0ICH2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0347161\|UniProtKB=A0A251U761	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0017101\|UniProtKB=A0A251VMI7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900461720\|UniProtKB=A0A9R1WTU0	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009722mg\|UniProtKB=A0A022RZW1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_23302\|UniProtKB=A0A1U8E1K2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400020283\|UniProtKB=M1BT38	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g018730.3\|UniProtKB=A0A3Q7IWA6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107828186\|UniProtKB=A0A1S4DBY4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi04g01763\|UniProtKB=A5AU65	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E04242\|UniProtKB=A0A059CAW0	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A07P32920.1\|UniProtKB=A0A078F749	Brassica napus	LDO
BRANA\|Gene_ORFName=DARMORV10_C06P39140.1\|UniProtKB=A0A078HNV3	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra004123\|UniProtKB=M4CIT9	Brassica campestris	LDO
ARATH\|TAIR=locus=2171312\|UniProtKB=Q9FFF2	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2018516\|UniProtKB=O04482	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107949487\|UniProtKB=A0A1U8NNJ6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951863\|UniProtKB=A0A1U8NWQ5	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_024461\|UniProtKB=A0A061EWP2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g019907mg\|UniProtKB=A0A067ER35	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G130400v3\|UniProtKB=B9H3Y8	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_017G075200v3\|UniProtKB=B9IJQ6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_15G189000\|UniProtKB=A0A2C9UIC4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1298200\|UniProtKB=B9S046	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G170500\|UniProtKB=I1LBV4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G219500\|UniProtKB=I1NIJ5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g078300\|UniProtKB=A0A072VY12	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_23520\|UniProtKB=A0A2I4G288	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_31100\|UniProtKB=A0A6P9EJ73	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G652300\|UniProtKB=A0A0A0KSX7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G335400\|UniProtKB=M5XX13	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_94540\|UniProtKB=D8RHZ4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_231325\|UniProtKB=D8REF4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c16_12470\|UniProtKB=A0A2K1J8B0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0070s0050\|UniProtKB=A0A2R6WP02	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000500440\|UniProtKB=A0A1Y1HNS5	Klebsormidium nitens	LDO