PANTHER Gene Information

Gene Symbol(s):

MCM2

Organism:

Bos taurus

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Tree

Gene Name:

DNA replication licensing factor MCM2

Gene ID:

ENSBTAG00000014380.6

Protein ID:

F1N506

Persistent Id:

PTN000179931

Alternate Ids:

ENSBTAP00000019121(Ensembl_PRO)	F1N506_BOVIN(UniProtKB-ID)
F1N506(Synonym)	ENSBTAG00000014380(Ensembl)
ENSBTAT00000019121(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER (PTHR11630)
PANTHER Subfamily:	DNA REPLICATION LICENSING FACTOR MCM2 (PTHR11630:SF44)
PANTHER GO-slim Molecular Function:	single-stranded DNA binding 3'-5' DNA helicase activity single-stranded DNA helicase activity
PANTHER GO-slim Biological Process:	DNA unwinding involved in DNA replication mitotic DNA replication initiation double-strand break repair via break-induced replication
PANTHER GO-slim Cellular Component:	MCM complex nucleus
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA replication origin binding, ATP binding, histone binding, metal ion binding, helicase activity, 3'-5' DNA helicase activity, single-stranded DNA helicase activity, single-stranded DNA binding, hydrolase activity, enzyme binding
GO BP Complete:	DNA replication initiation, cochlea development, double-strand break repair via break-induced replication, apoptotic process, cellular response to interleukin-4, mitotic DNA replication initiation, DNA unwinding involved in DNA replication, nucleosome assembly
GO CC Complete:	nucleus, CMG complex, cytoplasm, nuclear origin of replication recognition complex, chromatin, MCM complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6944\|UniProtKB=P49736	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015345.4\|UniProtKB=H2QNA7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014866.3\|UniProtKB=G3RFX4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000158.4\|UniProtKB=F7HLV9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=105380\|UniProtKB=P97310	Mus musculus	LDO
RAT\|RGD=1305577\|UniProtKB=D3ZP96	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000011624.5\|UniProtKB=A0A5G2Q7I1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019631.4\|UniProtKB=F7DDB3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013550.6\|UniProtKB=M3WJ18	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013762.1\|UniProtKB=A0A8I3NR86	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007891.4\|UniProtKB=F6ZG72	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007166.4\|UniProtKB=F6XZD4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028179.1\|UniProtKB=A0A8V1AFJ9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007455.4\|UniProtKB=G1KGN1	Anolis carolinensis	LDO
XENLA\|Gene=mcm2.S\|UniProtKB=A0A1L8GHP1	Xenopus laevis	O
XENLA\|Gene=mcm2\|UniProtKB=P55861	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-999974\|UniProtKB=Q6DIH3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000003191.2\|UniProtKB=H2LDG8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020419-24\|UniProtKB=A0A0R4IF65	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013582.1\|UniProtKB=W5N7Z7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118415588\|UniProtKB=A0A9J7L4X2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579797\|UniProtKB=A0A7M7MXP7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003154\|UniProtKB=Q9XXI9	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037858\|UniProtKB=A8XTB1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00115569\|UniProtKB=A0A8R1UI54	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00204739\|UniProtKB=A0A2A6BYN8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0014861\|UniProtKB=P49735	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004275\|UniProtKB=Q7QAZ2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011437\|UniProtKB=D6X4M6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_306072\|UniProtKB=E9GUG3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016696\|UniProtKB=B7PAS1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG191161\|UniProtKB=T1FSP0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g191344\|UniProtKB=A7SMI2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63837\|UniProtKB=B3RUX5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_36175\|UniProtKB=A9UTK0	Monosiga brevicollis	LDO
YEAST\|SGD=S000000119\|UniProtKB=P29469	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR178W\|UniProtKB=Q753Z4	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000193282\|UniProtKB=Q5A034	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F04664g\|UniProtKB=Q6C2W1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02491\|UniProtKB=C8VPB7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G14010\|UniProtKB=Q4WYR8	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU04327\|UniProtKB=Q1K713	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01022\|UniProtKB=A7E6U7	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03155\|UniProtKB=Q0UYK9	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC4.04c\|UniProtKB=P40377	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02348\|UniProtKB=B6K281	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNG02380\|UniProtKB=Q5KDY4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01445\|UniProtKB=A0A0D1E288	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_15535\|UniProtKB=E3KYG5	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_19082\|UniProtKB=F4NXZ8	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_117970\|UniProtKB=C4LYY1	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0286623\|UniProtKB=Q54LI2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_155563\|UniProtKB=F0ZUC1	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_28_0850\|UniProtKB=Q4Q8I2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.5730\|UniProtKB=Q384N2	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_15344\|UniProtKB=A8B5Y5	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_122470\|UniProtKB=A2DN04	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1417800\|UniProtKB=Q8ILR7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00030731001\|UniProtKB=A0BNH6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_29936\|UniProtKB=B8CC29	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GAJ9_PHYRM\|UniProtKB=H3GAJ9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g338000v5\|UniProtKB=A8JCF0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00016p00242770\|UniProtKB=W1PEG8	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_122G00750\|UniProtKB=A0A0K9Q2T4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g27530\|UniProtKB=A0A804KPC0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g27520\|UniProtKB=A0A804KPB9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_025993mg\|UniProtKB=K3ZHE1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3005G110535\|UniProtKB=C6JS28	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb169610\|UniProtKB=K7UQQ7	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os11g0484300\|UniProtKB=Q2R482	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g19207v3\|UniProtKB=I1ILT0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0065100\|UniProtKB=A0A8I6W6Q7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G264000\|UniProtKB=A0A3B5Y2X7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G264100\|UniProtKB=A0A3B5ZW55	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G274600\|UniProtKB=A0A3B5YZ96	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_009209\|UniProtKB=A0A1U7ZLM5	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110778051\|UniProtKB=A0A9R0HWI3	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0254751\|UniProtKB=A0A251UJ27	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300114240\|UniProtKB=A0A9R1W6Z3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000889mg\|UniProtKB=A0A022QEM8	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_14072\|UniProtKB=A0A1U8FDH5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400002190\|UniProtKB=M0ZQ54	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g040120.2\|UniProtKB=A0A3Q7JLR8	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107808167\|UniProtKB=A0A1S4BH15	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805831\|UniProtKB=A0A1S4B987	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi01g01799\|UniProtKB=D7TFL2	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B03569\|UniProtKB=A0A059D8G3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00041200001\|UniProtKB=A0A078JDK4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00059834001\|UniProtKB=A0A078HF62	Brassica napus	O
BRACM\|EnsemblGenome=Bra014033\|UniProtKB=M4DC21	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00061980001\|UniProtKB=A0A078FHW8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra040301\|UniProtKB=M4FGS3	Brassica campestris	LDO
ARATH\|TAIR=locus=2028240\|UniProtKB=Q9LPD9	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107888453\|UniProtKB=A0A1U8HPU7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107910656\|UniProtKB=A0A1U8JV11	Gossypium hirsutum	O
GOSHI\|Gene=LOC107888519\|UniProtKB=A0A1U8HW27	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_003529\|UniProtKB=A0A061DN18	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g002353mg\|UniProtKB=A0A067DVM1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G070500v3\|UniProtKB=U5GPA0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_08G099300\|UniProtKB=A0A2C9VEZ5	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1438760\|UniProtKB=B9RG29	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G035000\|UniProtKB=I1MRS5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_07G238400\|UniProtKB=I1KMP8	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g122270\|UniProtKB=G7JNY1	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_15100\|UniProtKB=A0A2I4GCH3	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr16_15110\|UniProtKB=A0A2I4GCJ0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G722880\|UniProtKB=A0A0A0LCK0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G211500\|UniProtKB=M5XKD5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_179032\|UniProtKB=D8SEJ2	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_88537\|UniProtKB=D8R9W4	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c1_34820\|UniProtKB=A0A2K1LAY1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0007s0014\|UniProtKB=A0A2R6XN60	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004220010\|UniProtKB=A0A1Y1IEH0	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0242\|UniProtKB=A9A310	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1352\|UniProtKB=B1L6L9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0774\|UniProtKB=Q9UXG1	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0901\|UniProtKB=Q8ZY88	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3829\|UniProtKB=Q8TJF6	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0681\|UniProtKB=Q8TSW4	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_ECL13\|UniProtKB=Q60275	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_1489\|UniProtKB=Q58884	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0363\|UniProtKB=Q57809	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0961\|UniProtKB=Q58371	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_2181G\|UniProtKB=Q9HNA5	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1361\|UniProtKB=Q5JGW1	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK0096\|UniProtKB=Q5JEJ0	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK1620\|UniProtKB=Q5JIT1	Thermococcus kodakaraensis	O