PANTHER Gene Information

Gene Symbol(s):

NCU04327

Organism:

Neurospora crassa

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Gene Name:

DNA replication licensing factor MCM2

Gene ID:

NCU04327

Protein ID:

Q1K713

Persistent Id:

PTN002267452

Alternate Ids:

85100478(GI)	XM_955880(refSeq)
Q1K713(Synonym)	3877114(GeneID)
CM002240(EMBL)	EAA31737(EMBL-CDS)
Q1K713_NEUCR(UniProtKB-ID)	NCU04327(Ensembl)
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PANTHER Classification

PANTHER Family:	DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER (PTHR11630)
PANTHER Subfamily:	DNA REPLICATION LICENSING FACTOR MCM2 (PTHR11630:SF44)
PANTHER GO-slim Molecular Function:	single-stranded DNA binding 3'-5' DNA helicase activity single-stranded DNA helicase activity
PANTHER GO-slim Biological Process:	DNA unwinding involved in DNA replication mitotic DNA replication initiation double-strand break repair via break-induced replication
PANTHER GO-slim Cellular Component:	MCM complex nucleus
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	double-stranded DNA helicase activity, helicase activity, four-way junction helicase activity, chromatin binding, forked DNA-dependent helicase activity, 3'-5' DNA helicase activity, single-stranded DNA binding, DNA binding, DNA replication origin binding, ATP binding, metal ion binding, single-stranded 3'-5' DNA helicase activity, single-stranded DNA helicase activity, hydrolase activity
GO BP Complete:	DNA replication initiation, double-strand break repair via break-induced replication, DNA replication, DNA strand elongation involved in DNA replication, DNA duplex unwinding, pre-replicative complex assembly involved in nuclear cell cycle DNA replication, mitotic DNA replication initiation, DNA damage response, DNA unwinding involved in DNA replication, premeiotic DNA replication, DNA replication-dependent chromatin assembly
GO CC Complete:	heterochromatin, nucleus, nuclear pre-replicative complex, CMG complex, cytoplasm, DNA replication preinitiation complex, nuclear replication fork, chromosome, telomeric repeat region, replication fork protection complex, chromatin, MCM complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6944\|UniProtKB=P49736	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015345.4\|UniProtKB=H2QNA7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014866.3\|UniProtKB=G3RFX4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000158.4\|UniProtKB=F7HLV9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=105380\|UniProtKB=P97310	Mus musculus	LDO
RAT\|RGD=1305577\|UniProtKB=D3ZP96	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014380.6\|UniProtKB=F1N506	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011624.5\|UniProtKB=A0A5G2Q7I1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019631.4\|UniProtKB=F7DDB3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013550.6\|UniProtKB=M3WJ18	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013762.1\|UniProtKB=A0A8I3NR86	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007891.4\|UniProtKB=F6ZG72	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007166.4\|UniProtKB=F6XZD4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028179.1\|UniProtKB=A0A8V1AFJ9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007455.4\|UniProtKB=G1KGN1	Anolis carolinensis	LDO
XENLA\|Gene=mcm2.S\|UniProtKB=A0A1L8GHP1	Xenopus laevis	O
XENLA\|Gene=mcm2\|UniProtKB=P55861	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-999974\|UniProtKB=Q6DIH3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000003191.2\|UniProtKB=H2LDG8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020419-24\|UniProtKB=A0A0R4IF65	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013582.1\|UniProtKB=W5N7Z7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118415588\|UniProtKB=A0A9J7L4X2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579797\|UniProtKB=A0A7M7MXP7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003154\|UniProtKB=Q9XXI9	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037858\|UniProtKB=A8XTB1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00115569\|UniProtKB=A0A8R1UI54	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00204739\|UniProtKB=A0A2A6BYN8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0014861\|UniProtKB=P49735	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004275\|UniProtKB=Q7QAZ2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011437\|UniProtKB=D6X4M6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_306072\|UniProtKB=E9GUG3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016696\|UniProtKB=B7PAS1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG191161\|UniProtKB=T1FSP0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g191344\|UniProtKB=A7SMI2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63837\|UniProtKB=B3RUX5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_36175\|UniProtKB=A9UTK0	Monosiga brevicollis	LDO
YEAST\|SGD=S000000119\|UniProtKB=P29469	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR178W\|UniProtKB=Q753Z4	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000193282\|UniProtKB=Q5A034	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F04664g\|UniProtKB=Q6C2W1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02491\|UniProtKB=C8VPB7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G14010\|UniProtKB=Q4WYR8	Neosartorya fumigata	LDO
SCLS1\|EnsemblGenome=SS1G_01022\|UniProtKB=A7E6U7	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03155\|UniProtKB=Q0UYK9	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC4.04c\|UniProtKB=P40377	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02348\|UniProtKB=B6K281	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNG02380\|UniProtKB=Q5KDY4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01445\|UniProtKB=A0A0D1E288	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_15535\|UniProtKB=E3KYG5	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_19082\|UniProtKB=F4NXZ8	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_117970\|UniProtKB=C4LYY1	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0286623\|UniProtKB=Q54LI2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_155563\|UniProtKB=F0ZUC1	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_28_0850\|UniProtKB=Q4Q8I2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.5730\|UniProtKB=Q384N2	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_15344\|UniProtKB=A8B5Y5	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_122470\|UniProtKB=A2DN04	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1417800\|UniProtKB=Q8ILR7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00030731001\|UniProtKB=A0BNH6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_29936\|UniProtKB=B8CC29	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GAJ9_PHYRM\|UniProtKB=H3GAJ9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g338000v5\|UniProtKB=A8JCF0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00016p00242770\|UniProtKB=W1PEG8	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_122G00750\|UniProtKB=A0A0K9Q2T4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g27530\|UniProtKB=A0A804KPC0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g27520\|UniProtKB=A0A804KPB9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_025993mg\|UniProtKB=K3ZHE1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3005G110535\|UniProtKB=C6JS28	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb169610\|UniProtKB=K7UQQ7	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os11g0484300\|UniProtKB=Q2R482	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g19207v3\|UniProtKB=I1ILT0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0065100\|UniProtKB=A0A8I6W6Q7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G264000\|UniProtKB=A0A3B5Y2X7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G264100\|UniProtKB=A0A3B5ZW55	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G274600\|UniProtKB=A0A3B5YZ96	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_009209\|UniProtKB=A0A1U7ZLM5	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110778051\|UniProtKB=A0A9R0HWI3	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0254751\|UniProtKB=A0A251UJ27	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300114240\|UniProtKB=A0A9R1W6Z3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000889mg\|UniProtKB=A0A022QEM8	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_14072\|UniProtKB=A0A1U8FDH5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400002190\|UniProtKB=M0ZQ54	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g040120.2\|UniProtKB=A0A3Q7JLR8	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107808167\|UniProtKB=A0A1S4BH15	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805831\|UniProtKB=A0A1S4B987	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi01g01799\|UniProtKB=D7TFL2	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B03569\|UniProtKB=A0A059D8G3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00041200001\|UniProtKB=A0A078JDK4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00059834001\|UniProtKB=A0A078HF62	Brassica napus	O
BRACM\|EnsemblGenome=Bra014033\|UniProtKB=M4DC21	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00061980001\|UniProtKB=A0A078FHW8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra040301\|UniProtKB=M4FGS3	Brassica campestris	LDO
ARATH\|TAIR=locus=2028240\|UniProtKB=Q9LPD9	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107888453\|UniProtKB=A0A1U8HPU7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107910656\|UniProtKB=A0A1U8JV11	Gossypium hirsutum	O
GOSHI\|Gene=LOC107888519\|UniProtKB=A0A1U8HW27	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_003529\|UniProtKB=A0A061DN18	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g002353mg\|UniProtKB=A0A067DVM1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G070500v3\|UniProtKB=U5GPA0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_08G099300\|UniProtKB=A0A2C9VEZ5	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1438760\|UniProtKB=B9RG29	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G035000\|UniProtKB=I1MRS5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_07G238400\|UniProtKB=I1KMP8	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g122270\|UniProtKB=G7JNY1	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_15100\|UniProtKB=A0A2I4GCH3	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr16_15110\|UniProtKB=A0A2I4GCJ0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G722880\|UniProtKB=A0A0A0LCK0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G211500\|UniProtKB=M5XKD5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_179032\|UniProtKB=D8SEJ2	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_88537\|UniProtKB=D8R9W4	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c1_34820\|UniProtKB=A0A2K1LAY1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0007s0014\|UniProtKB=A0A2R6XN60	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004220010\|UniProtKB=A0A1Y1IEH0	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0242\|UniProtKB=A9A310	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1352\|UniProtKB=B1L6L9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0774\|UniProtKB=Q9UXG1	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0901\|UniProtKB=Q8ZY88	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3829\|UniProtKB=Q8TJF6	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0681\|UniProtKB=Q8TSW4	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_ECL13\|UniProtKB=Q60275	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_1489\|UniProtKB=Q58884	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0363\|UniProtKB=Q57809	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0961\|UniProtKB=Q58371	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_2181G\|UniProtKB=Q9HNA5	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1361\|UniProtKB=Q5JGW1	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK0096\|UniProtKB=Q5JEJ0	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK1620\|UniProtKB=Q5JIT1	Thermococcus kodakaraensis	O