PANTHER Gene Information

Gene Symbol(s):

SUZ12

Organism:

Bos taurus

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Tree

Gene Name:

SUZ12 polycomb repressive complex 2 subunit

Gene ID:

ENSBTAG00000018752.4

Protein ID:

A0A3Q1M792

Persistent Id:

PTN000502905

Alternate Ids:

A0A3Q1M792_BOVIN(UniProtKB-ID)	NM_001205587(refSeq)
ENSBTAP00000064270(Ensembl_PRO)	538774(GeneID)
A0A3Q1M792(Synonym)	ENSBTAT00000077887(Ensembl_TRS)
329663438(GI)	ENSBTAG00000018752(Ensembl)
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PANTHER Classification

PANTHER Family:	POLYCOMB GROUP PROTEIN (PTHR22597)
PANTHER Subfamily:	POLYCOMB PROTEIN SUZ12 (PTHR22597:SF0)
PANTHER GO-slim Molecular Function:	chromatin DNA binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	transcription corepressor binding, chromatin DNA binding, promoter-specific chromatin binding, metal ion binding, methylated histone binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, enzyme activator activity, lncRNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, cell population proliferation, oligodendrocyte differentiation, facultative heterochromatin formation, negative regulation of cell differentiation, random inactivation of X chromosome, positive regulation of cell population proliferation
GO CC Complete:	nucleus, nuclear body, ESC/E(Z) complex, protein-DNA complex, sex chromatin, nucleolus, RSC-type complex, ribonucleoprotein complex, chromatin silencing complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transcriptional Regulation by E2F6, SUMO E3 ligases SUMOylate target proteins, Generic Transcription Pathway, Cellular responses to stimuli, Post-translational protein modification, Gene expression (Transcription), Metabolism of proteins, PRC2 methylates histones and DNA, SUMOylation of chromatin organization proteins, Epigenetic regulation of gene expression, Oxidative Stress Induced Senescence, RNA Polymerase II Transcription, Chromatin organization, PKMTs methylate histone lysines, Cellular responses to stress, SUMOylation, Cellular Senescence, Chromatin modifying enzymes

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17101\|UniProtKB=Q15022	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051958.1\|UniProtKB=A0A2I3TSF3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000048549.1\|UniProtKB=A0A2I3SAS8	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000008980.5\|UniProtKB=H2QCM6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010352.3\|UniProtKB=G3R4A9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001116.4\|UniProtKB=F6PUM4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1261758\|UniProtKB=Q80U70	Mus musculus	LDO
RAT\|RGD=1593621\|UniProtKB=A0A8I6AIG5	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000017744.5\|UniProtKB=F1RKV6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019997.3\|UniProtKB=F7DCG7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023797.4\|UniProtKB=M3X7D9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013827.1\|UniProtKB=A0A8I3NRJ2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019204.4\|UniProtKB=F6ZIT8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005252.3\|UniProtKB=F6WDL4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029591.1\|UniProtKB=A0A8V1ADX2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009504.4\|UniProtKB=H9GFC2	Anolis carolinensis	LDO
XENLA\|Gene=suz12.S\|UniProtKB=C6GGW6	Xenopus laevis	O
XENLA\|Gene=suz12\|UniProtKB=A0A8J0TYF8	Xenopus laevis	O
XENLA\|Gene=suz12.L\|UniProtKB=A0A8J0TWW7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-997462\|UniProtKB=Q0VA03	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000839.2\|UniProtKB=H2L5F8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000003511.2\|UniProtKB=H2LEJ7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040801-36\|UniProtKB=Q6DC03	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-3255\|UniProtKB=B0R1D5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013792.1\|UniProtKB=W5N8Q0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014546.2\|UniProtKB=F6UZR0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425728\|UniProtKB=A0A9J7N3R5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583056\|UniProtKB=A0A7M7NTG7	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0020887\|UniProtKB=Q9NJG9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011881\|UniProtKB=A0A1S4H8Q7	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003521\|UniProtKB=D6WHD3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_304723\|UniProtKB=E9FW32	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023066\|UniProtKB=B7QLX9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g100352\|UniProtKB=A7S0W2	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_25042\|UniProtKB=A9UXL5	Monosiga brevicollis	LDO
YARLI\|EnsemblGenome=YALI0_E06369g\|UniProtKB=Q6C6T9	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_01219\|UniProtKB=C8VSS2	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G10600\|UniProtKB=Q4WT44	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03064\|UniProtKB=V5IRK1	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_15026\|UniProtKB=Q0TZM1	Phaeosphaeria nodorum	O
YEAST\|SGD=S000004697\|UniProtKB=P32832	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL042W\|UniProtKB=Q75DQ9	Eremothecium gossypii	O
CANAL\|CGD=CAL0000183327\|UniProtKB=A0A1D8PG62	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C12342g\|UniProtKB=Q6CC56	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04239\|UniProtKB=Q5B5E1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G06410\|UniProtKB=Q4WJD0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07290\|UniProtKB=Q7S977	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01123\|UniProtKB=A7E747	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_08460\|UniProtKB=Q0UIF4	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPCC1281.05\|UniProtKB=O94522	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03944\|UniProtKB=B6K5G9	Schizosaccharomyces japonicus	O
BATDJ\|Gene_ORFName=BATDEDRAFT_84646\|UniProtKB=F4NTH8	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000001845\|UniProtKB=P43554	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ABR244C\|UniProtKB=Q75CX8	Eremothecium gossypii	LDO
NEUCR\|EnsemblGenome=NCU05460\|UniProtKB=Q7RUQ4	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07791\|UniProtKB=A7ER38	Sclerotinia sclerotiorum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_5265\|UniProtKB=B8C2F4	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GCJ7_PHYRM\|UniProtKB=H3GCJ7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g456800v5\|UniProtKB=A0A2K3DBK9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00111p00131260\|UniProtKB=W1NY21	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_30G00410\|UniProtKB=A0A0K9PC27	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g13060\|UniProtKB=A0A804I293	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_029239mg\|UniProtKB=K3ZRK9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G164300\|UniProtKB=A0A1W0W4A9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb309520\|UniProtKB=A0A804UDF5	Zea mays	O
SETIT\|EnsemblGenome=SETIT_034803mg\|UniProtKB=K4A7E7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G015500\|UniProtKB=A0A1B6PJF5	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3001G087600\|UniProtKB=A0A1B6QHZ0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb057460\|UniProtKB=A0A1D6L4S6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os04g0162100\|UniProtKB=Q0JF48	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os09g0306800\|UniProtKB=Q69KN0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g11608v3\|UniProtKB=A0A0Q3IML7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0095780\|UniProtKB=M0YN29	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G020400\|UniProtKB=A0A3B6BX21	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G002500\|UniProtKB=A0A3B6AQ75	Triticum aestivum	O
BRADI\|EnsemblGenome=BRADI_3g03106v3\|UniProtKB=I1HWY0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0095480\|UniProtKB=M0XYE9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G023900\|UniProtKB=A0A3B6BZL5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G000100\|UniProtKB=A0A3B6ANZ2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G000600\|UniProtKB=A0A3B6D4F3	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0472220\|UniProtKB=M0Y192	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G179600\|UniProtKB=A0A3B6KHF9	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G184200\|UniProtKB=A0A3B6MQZ4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G177400\|UniProtKB=A0A3B6LLD6	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_019844\|UniProtKB=A0A1U8B7A4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110797242\|UniProtKB=A0A9R0K4C5	Spinacia oleracea	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E00374\|UniProtKB=A0A059C0D8	Eucalyptus grandis	LDO
GOSHI\|Gene=LOC107932375\|UniProtKB=A0A1U8LZ39	Gossypium hirsutum	O
GOSHI\|Gene=LOC107933743\|UniProtKB=A0A1U8M7K7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_015891\|UniProtKB=A0A061G319	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_003G081400v3\|UniProtKB=B9GYN4	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G086000\|UniProtKB=A0A2C9WIX8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0191350\|UniProtKB=B9T283	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_01G206000\|UniProtKB=I1J9S4	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_11G036800\|UniProtKB=A0A0R0HLN7	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g013150\|UniProtKB=G7JXG2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_05710\|UniProtKB=A0A2I4F0E0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G017280\|UniProtKB=A0A0A0L461	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G060700\|UniProtKB=A0A251P4F5	Prunus persica	LDO
NELNU\|Gene=LOC104598418\|UniProtKB=A0A1U7ZY49	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110782317\|UniProtKB=A0A9R0I3T6	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr14g0461041\|UniProtKB=A0A251SLZ1	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr14g0461151\|UniProtKB=A0A251SLW6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0167771\|UniProtKB=A0A251UYI5	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0166561\|UniProtKB=A0A251UYQ2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0668261\|UniProtKB=A0A251SNH7	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0668121\|UniProtKB=A0A9K3H8P6	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0668271\|UniProtKB=A0A9K3EEV2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0336371\|UniProtKB=A0A251U4Y9	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800393220\|UniProtKB=A0A9R1WXP4	Lactuca sativa	LDO
CAPAN\|EnsemblGenome=T459_08707\|UniProtKB=A0A2G2ZXC4	Capsicum annuum	LDO
CAPAN\|EnsemblGenome=T459_01490\|UniProtKB=A0A1U8H0Y1	Capsicum annuum	LDO
TOBAC\|Gene=LOC107788047\|UniProtKB=A0A1S3ZLP1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107829159\|UniProtKB=A0A1S4DF54	Nicotiana tabacum	O
TOBAC\|Gene=LOC107804934\|UniProtKB=A0A1S4B6E8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107762027\|UniProtKB=A0A1S3X7F2	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_02s0234g00050\|UniProtKB=F6HCX4	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi16g00341\|UniProtKB=F6I2N5	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A02925\|UniProtKB=A0A059DKE9	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P11580.1\|UniProtKB=A0A078H3F4	Brassica napus	O
BRACM\|EnsemblGenome=Bra005262\|UniProtKB=M4CM25	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00050335001\|UniProtKB=A0A078H2G9	Brassica napus	O
BRACM\|EnsemblGenome=Bra005316\|UniProtKB=M4CM79	Brassica campestris	O
ARATH\|TAIR=locus=2005510\|UniProtKB=P0DKJ8	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00058999001\|UniProtKB=A0A078HCV0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A01P20390.1\|UniProtKB=A0A078I1J1	Brassica napus	O
BRACM\|EnsemblGenome=Bra040097\|UniProtKB=M4FG70	Brassica campestris	O
BRACM\|EnsemblGenome=Bra021078\|UniProtKB=M4DX32	Brassica campestris	O
ARATH\|TAIR=locus=3685330\|UniProtKB=Q8W5B1	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A02P12420.1\|UniProtKB=A0A078FPD6	Brassica napus	O
BRACM\|EnsemblGenome=Bra022541\|UniProtKB=M4E193	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00066698001\|UniProtKB=A0A078HLT3	Brassica napus	O
BRACM\|EnsemblGenome=Bra029179\|UniProtKB=M4EK62	Brassica campestris	O
BRACM\|EnsemblGenome=Bra015201\|UniProtKB=A0A3P6CRS8	Brassica campestris	O
BRACM\|EnsemblGenome=Bra015200\|UniProtKB=A0A3P6D9P5	Brassica campestris	LDO
ARATH\|TAIR=locus=2129171\|UniProtKB=B3H7I2	Arabidopsis thaliana	O
ARATH\|EnsemblGenome=AT5G51230\|UniProtKB=Q8L6Y4	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107953615\|UniProtKB=A0A1U8NZR9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107911098\|UniProtKB=A0A1U8JW23	Gossypium hirsutum	O
GOSHI\|Gene=LOC107947336\|UniProtKB=A0A1U8NHY5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107949681\|UniProtKB=A0A1U8NPA9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_014839\|UniProtKB=A0A061G6W7	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_001G080200v3\|UniProtKB=A0A2K2BU79	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_003G150500v3\|UniProtKB=A0A2K2B7F1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_06G130800\|UniProtKB=A0A251KQ18	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_14G039200\|UniProtKB=A0A2C9UII1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1502370\|UniProtKB=B9R9Z3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G193800\|UniProtKB=K7LKC7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G069800\|UniProtKB=K7N203	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_19G225100\|UniProtKB=K7MZQ9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G118800\|UniProtKB=K7LIV1	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g090240\|UniProtKB=G7I2Z8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_24330\|UniProtKB=A0A2I4FHJ2	Juglans regia	O
JUGRE\|EnsemblGenome=Jr08_05710\|UniProtKB=A0A6P9ENU9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G024050\|UniProtKB=A0A0A0KZ77	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G152500\|UniProtKB=A0A251PKZ2	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c5_24460\|UniProtKB=A0A2K1KKX6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c6_4460\|UniProtKB=A0A2K1KEB5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c25_12300\|UniProtKB=A0A2K1IEM7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0092s0032\|UniProtKB=A0A2R6WGS7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000850310\|UniProtKB=A0A1Y1HSL2	Klebsormidium nitens	LDO