PANTHER Gene Information

Gene Symbol(s):

SUZ12

Organism:

Macaca mulatta

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Gene Name:

SUZ12 polycomb repressive complex 2 subunit

Gene ID:

ENSMMUG00000001116.4

Protein ID:

F6PUM4

Persistent Id:

PTN001097729

Alternate Ids:

F6PUM4(Synonym)	967029756(GI)
ENSMMUP00000001483(Ensembl_PRO)	ENSMMUT00000001577(Ensembl_TRS)
F6PUM4_MACMU(UniProtKB-ID)	717834(GeneID)
ENSMMUG00000001116(Ensembl)	XP_014974503(refSeq)
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PANTHER Classification

PANTHER Family:	POLYCOMB GROUP PROTEIN (PTHR22597)
PANTHER Subfamily:	POLYCOMB PROTEIN SUZ12 (PTHR22597:SF0)
PANTHER GO-slim Molecular Function:	chromatin DNA binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	transcription corepressor binding, chromatin DNA binding, RNA binding, promoter-specific chromatin binding, metal ion binding, methylated histone binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, enzyme activator activity, sequence-specific DNA binding, chromatin binding, lncRNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, cell population proliferation, oligodendrocyte differentiation, facultative heterochromatin formation, negative regulation of cell differentiation, random inactivation of X chromosome, positive regulation of cell population proliferation, chromatin organization
GO CC Complete:	nucleus, nuclear body, ESC/E(Z) complex, protein-DNA complex, sex chromatin, nucleolus, RSC-type complex, ribonucleoprotein complex, chromatin silencing complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17101\|UniProtKB=Q15022	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051958.1\|UniProtKB=A0A2I3TSF3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000048549.1\|UniProtKB=A0A2I3SAS8	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000008980.5\|UniProtKB=H2QCM6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010352.3\|UniProtKB=G3R4A9	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1261758\|UniProtKB=Q80U70	Mus musculus	LDO
RAT\|RGD=1593621\|UniProtKB=A0A8I6AIG5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000018752.4\|UniProtKB=A0A3Q1M792	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017744.5\|UniProtKB=F1RKV6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019997.3\|UniProtKB=F7DCG7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023797.4\|UniProtKB=M3X7D9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013827.1\|UniProtKB=A0A8I3NRJ2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019204.4\|UniProtKB=F6ZIT8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005252.3\|UniProtKB=F6WDL4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029591.1\|UniProtKB=A0A8V1ADX2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009504.4\|UniProtKB=H9GFC2	Anolis carolinensis	LDO
XENLA\|Gene=suz12.S\|UniProtKB=C6GGW6	Xenopus laevis	O
XENLA\|Gene=suz12\|UniProtKB=A0A8J0TYF8	Xenopus laevis	O
XENLA\|Gene=suz12.L\|UniProtKB=A0A8J0TWW7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-997462\|UniProtKB=Q0VA03	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000839.2\|UniProtKB=H2L5F8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000003511.2\|UniProtKB=H2LEJ7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040801-36\|UniProtKB=Q6DC03	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-3255\|UniProtKB=B0R1D5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013792.1\|UniProtKB=W5N8Q0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014546.2\|UniProtKB=F6UZR0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425728\|UniProtKB=A0A9J7N3R5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583056\|UniProtKB=A0A7M7NTG7	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0020887\|UniProtKB=Q9NJG9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011881\|UniProtKB=A0A1S4H8Q7	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003521\|UniProtKB=D6WHD3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_304723\|UniProtKB=E9FW32	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023066\|UniProtKB=B7QLX9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g100352\|UniProtKB=A7S0W2	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_25042\|UniProtKB=A9UXL5	Monosiga brevicollis	LDO
YARLI\|EnsemblGenome=YALI0_E06369g\|UniProtKB=Q6C6T9	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_01219\|UniProtKB=C8VSS2	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G10600\|UniProtKB=Q4WT44	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03064\|UniProtKB=V5IRK1	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_15026\|UniProtKB=Q0TZM1	Phaeosphaeria nodorum	O
YEAST\|SGD=S000004697\|UniProtKB=P32832	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL042W\|UniProtKB=Q75DQ9	Eremothecium gossypii	O
CANAL\|CGD=CAL0000183327\|UniProtKB=A0A1D8PG62	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C12342g\|UniProtKB=Q6CC56	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04239\|UniProtKB=Q5B5E1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G06410\|UniProtKB=Q4WJD0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07290\|UniProtKB=Q7S977	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01123\|UniProtKB=A7E747	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_08460\|UniProtKB=Q0UIF4	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPCC1281.05\|UniProtKB=O94522	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03944\|UniProtKB=B6K5G9	Schizosaccharomyces japonicus	O
BATDJ\|Gene_ORFName=BATDEDRAFT_84646\|UniProtKB=F4NTH8	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000001845\|UniProtKB=P43554	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ABR244C\|UniProtKB=Q75CX8	Eremothecium gossypii	LDO
NEUCR\|EnsemblGenome=NCU05460\|UniProtKB=Q7RUQ4	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07791\|UniProtKB=A7ER38	Sclerotinia sclerotiorum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_5265\|UniProtKB=B8C2F4	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GCJ7_PHYRM\|UniProtKB=H3GCJ7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g456800v5\|UniProtKB=A0A2K3DBK9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00111p00131260\|UniProtKB=W1NY21	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_30G00410\|UniProtKB=A0A0K9PC27	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g13060\|UniProtKB=A0A804I293	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_029239mg\|UniProtKB=K3ZRK9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G164300\|UniProtKB=A0A1W0W4A9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb309520\|UniProtKB=A0A804UDF5	Zea mays	O
SETIT\|EnsemblGenome=SETIT_034803mg\|UniProtKB=K4A7E7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G015500\|UniProtKB=A0A1B6PJF5	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3001G087600\|UniProtKB=A0A1B6QHZ0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb057460\|UniProtKB=A0A1D6L4S6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os04g0162100\|UniProtKB=Q0JF48	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os09g0306800\|UniProtKB=Q69KN0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g11608v3\|UniProtKB=A0A0Q3IML7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0095780\|UniProtKB=M0YN29	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G020400\|UniProtKB=A0A3B6BX21	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G002500\|UniProtKB=A0A3B6AQ75	Triticum aestivum	O
BRADI\|EnsemblGenome=BRADI_3g03106v3\|UniProtKB=I1HWY0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0095480\|UniProtKB=M0XYE9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G023900\|UniProtKB=A0A3B6BZL5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G000100\|UniProtKB=A0A3B6ANZ2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G000600\|UniProtKB=A0A3B6D4F3	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0472220\|UniProtKB=M0Y192	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G179600\|UniProtKB=A0A3B6KHF9	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G184200\|UniProtKB=A0A3B6MQZ4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G177400\|UniProtKB=A0A3B6LLD6	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_019844\|UniProtKB=A0A1U8B7A4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110797242\|UniProtKB=A0A9R0K4C5	Spinacia oleracea	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E00374\|UniProtKB=A0A059C0D8	Eucalyptus grandis	LDO
GOSHI\|Gene=LOC107932375\|UniProtKB=A0A1U8LZ39	Gossypium hirsutum	O
GOSHI\|Gene=LOC107933743\|UniProtKB=A0A1U8M7K7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_015891\|UniProtKB=A0A061G319	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_003G081400v3\|UniProtKB=B9GYN4	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G086000\|UniProtKB=A0A2C9WIX8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0191350\|UniProtKB=B9T283	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_01G206000\|UniProtKB=I1J9S4	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_11G036800\|UniProtKB=A0A0R0HLN7	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g013150\|UniProtKB=G7JXG2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_05710\|UniProtKB=A0A2I4F0E0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G017280\|UniProtKB=A0A0A0L461	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G060700\|UniProtKB=A0A251P4F5	Prunus persica	LDO
NELNU\|Gene=LOC104598418\|UniProtKB=A0A1U7ZY49	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110782317\|UniProtKB=A0A9R0I3T6	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr14g0461041\|UniProtKB=A0A251SLZ1	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr14g0461151\|UniProtKB=A0A251SLW6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0167771\|UniProtKB=A0A251UYI5	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0166561\|UniProtKB=A0A251UYQ2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0668261\|UniProtKB=A0A251SNH7	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0668121\|UniProtKB=A0A9K3H8P6	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0668271\|UniProtKB=A0A9K3EEV2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0336371\|UniProtKB=A0A251U4Y9	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800393220\|UniProtKB=A0A9R1WXP4	Lactuca sativa	LDO
CAPAN\|EnsemblGenome=T459_08707\|UniProtKB=A0A2G2ZXC4	Capsicum annuum	LDO
CAPAN\|EnsemblGenome=T459_01490\|UniProtKB=A0A1U8H0Y1	Capsicum annuum	LDO
TOBAC\|Gene=LOC107788047\|UniProtKB=A0A1S3ZLP1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107829159\|UniProtKB=A0A1S4DF54	Nicotiana tabacum	O
TOBAC\|Gene=LOC107804934\|UniProtKB=A0A1S4B6E8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107762027\|UniProtKB=A0A1S3X7F2	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_02s0234g00050\|UniProtKB=F6HCX4	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi16g00341\|UniProtKB=F6I2N5	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A02925\|UniProtKB=A0A059DKE9	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P11580.1\|UniProtKB=A0A078H3F4	Brassica napus	O
BRACM\|EnsemblGenome=Bra005262\|UniProtKB=M4CM25	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00050335001\|UniProtKB=A0A078H2G9	Brassica napus	O
BRACM\|EnsemblGenome=Bra005316\|UniProtKB=M4CM79	Brassica campestris	O
ARATH\|TAIR=locus=2005510\|UniProtKB=P0DKJ8	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00058999001\|UniProtKB=A0A078HCV0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A01P20390.1\|UniProtKB=A0A078I1J1	Brassica napus	O
BRACM\|EnsemblGenome=Bra040097\|UniProtKB=M4FG70	Brassica campestris	O
BRACM\|EnsemblGenome=Bra021078\|UniProtKB=M4DX32	Brassica campestris	O
ARATH\|TAIR=locus=3685330\|UniProtKB=Q8W5B1	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A02P12420.1\|UniProtKB=A0A078FPD6	Brassica napus	O
BRACM\|EnsemblGenome=Bra022541\|UniProtKB=M4E193	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00066698001\|UniProtKB=A0A078HLT3	Brassica napus	O
BRACM\|EnsemblGenome=Bra029179\|UniProtKB=M4EK62	Brassica campestris	O
BRACM\|EnsemblGenome=Bra015201\|UniProtKB=A0A3P6CRS8	Brassica campestris	O
BRACM\|EnsemblGenome=Bra015200\|UniProtKB=A0A3P6D9P5	Brassica campestris	LDO
ARATH\|TAIR=locus=2129171\|UniProtKB=B3H7I2	Arabidopsis thaliana	O
ARATH\|EnsemblGenome=AT5G51230\|UniProtKB=Q8L6Y4	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107953615\|UniProtKB=A0A1U8NZR9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107911098\|UniProtKB=A0A1U8JW23	Gossypium hirsutum	O
GOSHI\|Gene=LOC107947336\|UniProtKB=A0A1U8NHY5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107949681\|UniProtKB=A0A1U8NPA9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_014839\|UniProtKB=A0A061G6W7	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_001G080200v3\|UniProtKB=A0A2K2BU79	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_003G150500v3\|UniProtKB=A0A2K2B7F1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_06G130800\|UniProtKB=A0A251KQ18	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_14G039200\|UniProtKB=A0A2C9UII1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1502370\|UniProtKB=B9R9Z3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G193800\|UniProtKB=K7LKC7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G069800\|UniProtKB=K7N203	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_19G225100\|UniProtKB=K7MZQ9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G118800\|UniProtKB=K7LIV1	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g090240\|UniProtKB=G7I2Z8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_24330\|UniProtKB=A0A2I4FHJ2	Juglans regia	O
JUGRE\|EnsemblGenome=Jr08_05710\|UniProtKB=A0A6P9ENU9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G024050\|UniProtKB=A0A0A0KZ77	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G152500\|UniProtKB=A0A251PKZ2	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c5_24460\|UniProtKB=A0A2K1KKX6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c6_4460\|UniProtKB=A0A2K1KEB5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c25_12300\|UniProtKB=A0A2K1IEM7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0092s0032\|UniProtKB=A0A2R6WGS7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000850310\|UniProtKB=A0A1Y1HSL2	Klebsormidium nitens	LDO