PANTHER Gene Information   
Gene Symbol(s): NR3C1
Organism: Bos taurus
View Gene in Tree
Tree
Tree
Gene Name: Glucocorticoid receptor
Gene ID: ENSBTAG00000019472.6
Protein ID: F1MN19
Persistent Id: PTN000639388
Alternate Ids:
ENSBTAT00000025941(Ensembl_TRS) NP_001193563(refSeq)
ENSBTAG00000019472(Ensembl) F1MN19(Synonym)
F1MN19_BOVIN(UniProtKB-ID) 331284122(GI)
281946(GeneID) ENSBTAP00000025941(Ensembl_PRO)
Show All

PANTHER Classification
PANTHER Family: KNIRPS-RELATED PROTEIN-RELATED (PTHR48092)
PANTHER Subfamily: GLUCOCORTICOID RECEPTOR (PTHR48092:SF5)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
signaling receptor activity
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   GR
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, zinc ion binding, identical protein binding, estrogen response element binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, nuclear glucocorticoid receptor activity, core promoter sequence-specific DNA binding, nuclear receptor activity, steroid hormone binding, Hsp90 protein binding, TBP-class protein binding
GO BP Complete: microglia differentiation, nuclear receptor-mediated glucocorticoid signaling pathway, astrocyte differentiation, mammary gland duct morphogenesis, positive regulation of miRNA transcription, regulation of gluconeogenesis, glucocorticoid metabolic process, neuroinflammatory response, chromatin organization, glucocorticoid mediated signaling pathway, positive regulation of transcription by RNA polymerase II, positive regulation of neuron apoptotic process, motor behavior, regulation of transcription by RNA polymerase II, maternal behavior, negative regulation of transcription by RNA polymerase II, regulation of glucocorticoid biosynthetic process, cellular response to transforming growth factor beta stimulus, nuclear receptor-mediated steroid hormone signaling pathway, gene expression, cellular response to dexamethasone stimulus, adrenal gland development, synaptic transmission, glutamatergic
GO CC Complete: nucleus, centrosome, nuclear speck, mitochondrion, membrane, spindle, cytosol, protein-containing complex, synapse, chromatin
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Nuclear Receptor transcription pathway, Generic Transcription Pathway, SUMO E3 ligases SUMOylate target proteins, Cellular responses to stimuli, Post-translational protein modification, Gene expression (Transcription), Metabolism of proteins, HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand, RNA Polymerase II Transcription, SUMOylation of intracellular receptors, Cellular responses to stress, SUMOylation

Orthologs