PANTHER Gene Information   
Gene Symbol(s): NR3C1
Organism: Sus scrofa
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Gene Name: Glucocorticoid receptor
Gene ID: ENSSSCG00000014401.6
Protein ID: A0A287B660
Persistent Id: PTN008733007
Alternate Ids:
ENSSSCT00000044530(Ensembl_TRS) A0A287B660(Synonym)
ENSSSCP00000051794(Ensembl_PRO) ENSSSCG00000014401(Ensembl)
A0A287B660_PIG(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: KNIRPS-RELATED PROTEIN-RELATED (PTHR48092)
PANTHER Subfamily: GLUCOCORTICOID RECEPTOR (PTHR48092:SF5)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
signaling receptor activity
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   GR
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, zinc ion binding, identical protein binding, estrogen response element binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, nuclear glucocorticoid receptor activity, core promoter sequence-specific DNA binding, nuclear receptor activity, steroid hormone binding, Hsp90 protein binding, TBP-class protein binding
GO BP Complete: microglia differentiation, nuclear receptor-mediated glucocorticoid signaling pathway, astrocyte differentiation, mammary gland duct morphogenesis, positive regulation of miRNA transcription, regulation of gluconeogenesis, glucocorticoid metabolic process, neuroinflammatory response, chromatin organization, glucocorticoid mediated signaling pathway, positive regulation of transcription by RNA polymerase II, positive regulation of neuron apoptotic process, motor behavior, regulation of transcription by RNA polymerase II, maternal behavior, negative regulation of transcription by RNA polymerase II, regulation of glucocorticoid biosynthetic process, cellular response to transforming growth factor beta stimulus, nuclear receptor-mediated steroid hormone signaling pathway, gene expression, cellular response to dexamethasone stimulus, adrenal gland development, synaptic transmission, glutamatergic
GO CC Complete: nucleus, centrosome, nuclear speck, mitochondrion, membrane, spindle, cytosol, protein-containing complex, synapse, chromatin
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular responses to stress, Nuclear Receptor transcription pathway, Generic Transcription Pathway, SUMOylation of intracellular receptors, SUMO E3 ligases SUMOylate target proteins, HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand, Cellular responses to stimuli, SUMOylation, Metabolism of proteins, RNA Polymerase II Transcription, Post-translational protein modification, Gene expression (Transcription)

Orthologs