PANTHER Gene Information   
Gene Symbol(s): NEFL
Organism: Bos taurus
View Gene in Tree
Tree
Tree
Gene Name: Neurofilament light polypeptide
Gene ID: ENSBTAG00000021949
Protein ID: P02548
Persistent Id: PTN000581308
Alternate Ids:
U83919(EMBL) 27806523(GI)
NEFL(Symbol) NFL(Synonym)
NP_776546(refSeq) ENSBTAT00000029264(Ensembl_TRS)
NFL_BOVIN(UniProtKB-ID) P79127(AltAccession)
281348(GeneID) AAB41543(EMBL-CDS)
ENSBTAG00000021949(Ensembl) ENSBTAP00000029264(Ensembl_PRO)
Show All

PANTHER Classification
PANTHER Family: GLIAL FIBRILLARY ACIDIC PROTEIN (PTHR45652)
PANTHER Subfamily: NEUROFILAMENT LIGHT POLYPEPTIDE (PTHR45652:SF8)  
PANTHER GO-slim Molecular Function: structural constituent of cytoskeleton
PANTHER GO-slim Biological Process: intermediate filament organization
cellular component assembly
PANTHER GO-slim Cellular Component: postsynapse
axon
cytoplasm
intermediate filament
PANTHER protein class: intermediate filament
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, protein binding, structural constituent of postsynaptic intermediate filament cytoskeleton, structural constituent of cytoskeleton, protein-macromolecule adaptor activity
GO BP Complete: regulation of synapse maturation, peripheral nervous system axon regeneration, anterograde axonal transport, neurofilament bundle assembly, locomotion, neurofilament cytoskeleton organization, neuron projection morphogenesis, postsynaptic modulation of chemical synaptic transmission, microtubule cytoskeleton organization, intermediate filament organization, postsynaptic intermediate filament cytoskeleton organization, negative regulation of neuron apoptotic process, positive regulation of axonogenesis, motor neuron apoptotic process, axonogenesis, intermediate filament bundle assembly, axonal transport of mitochondrion, regulation of axon diameter, negative regulation of motor neuron apoptotic process, retrograde axonal transport, neuromuscular process controlling balance
GO CC Complete: Schaffer collateral - CA1 synapse, cholinergic synapse, axon cytoplasm, cytoplasm, intermediate filament, neuromuscular junction, postsynaptic intermediate filament cytoskeleton, presynaptic intermediate filament cytoskeleton, neurofilament, axon
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: MAPK1/MAPK3 signaling, Transmission across Chemical Synapses, Neuronal System, Unblocking of NMDA receptors, glutamate binding and activation, Neurotransmitter receptors and postsynaptic signal transmission, Signal Transduction, Activation of NMDA receptors and postsynaptic events, RAF/MAP kinase cascade, MAPK family signaling cascades

Orthologs