PANTHER Gene Information

Gene Symbol(s):

NEFL

Organism:

Felis catus

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Gene Name:

Neurofilament light chain

Gene ID:

ENSFCAG00000013441.6

Protein ID:

A0A337SJ89

Persistent Id:

PTN001905989

Alternate Ids:

ENSFCAP00000047996(Ensembl_PRO)	101081039(GeneID)
A0A337SJ89(Synonym)	ENSFCAT00000051846(Ensembl_TRS)
ENSFCAG00000013441(Ensembl)	AANG04002583(EMBL)
XM_003984682(refSeq)	410956200(GI)
A0A337SJ89_FELCA(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	GLIAL FIBRILLARY ACIDIC PROTEIN (PTHR45652)
PANTHER Subfamily:	NEUROFILAMENT LIGHT POLYPEPTIDE (PTHR45652:SF8)
PANTHER GO-slim Molecular Function:	structural constituent of cytoskeleton
PANTHER GO-slim Biological Process:	intermediate filament organization cellular component assembly
PANTHER GO-slim Cellular Component:	postsynapse axon cytoplasm intermediate filament
PANTHER protein class:	intermediate filament

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	identical protein binding, structural constituent of postsynaptic intermediate filament cytoskeleton, structural constituent of cytoskeleton, protein-macromolecule adaptor activity
GO BP Complete:	regulation of synapse maturation, peripheral nervous system axon regeneration, anterograde axonal transport, neurofilament bundle assembly, locomotion, neurofilament cytoskeleton organization, neuron projection morphogenesis, postsynaptic modulation of chemical synaptic transmission, microtubule cytoskeleton organization, intermediate filament organization, postsynaptic intermediate filament cytoskeleton organization, positive regulation of axonogenesis, motor neuron apoptotic process, axonogenesis, intermediate filament bundle assembly, axonal transport of mitochondrion, regulation of axon diameter, negative regulation of motor neuron apoptotic process, retrograde axonal transport, neuromuscular process controlling balance
GO CC Complete:	axon cytoplasm, intermediate filament, postsynaptic intermediate filament cytoskeleton, presynaptic intermediate filament cytoskeleton, neurofilament, cell projection, neuron projection, Schaffer collateral - CA1 synapse, cytoskeleton, cholinergic synapse, cytoplasm, neuromuscular junction, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7739\|UniProtKB=P07196	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000045792.1\|UniProtKB=A0A2I3SJH8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001429.3\|UniProtKB=G3RNG2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003348.4\|UniProtKB=F7ED68	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97313\|UniProtKB=P08551	Mus musculus	LDO
RAT\|RGD=621458\|UniProtKB=P19527	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021949\|UniProtKB=P02548	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009649.5\|UniProtKB=A0A287BNA7	Sus scrofa	LDO
PIG\|Gene=NEFL\|UniProtKB=P02547	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022890.3\|UniProtKB=F6W6H2	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845014438.1\|UniProtKB=A0A8I3NI39	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016731.4\|UniProtKB=F6S064	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009794.5\|UniProtKB=F6STZ9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018944.1\|UniProtKB=A0A8V0Z8M9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011170.4\|UniProtKB=H9GHF8	Anolis carolinensis	LDO
XENLA\|Gene=nefl\|UniProtKB=P35616	Xenopus laevis	O
XENLA\|Gene=nefl.S\|UniProtKB=A0A1L8GRP7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-492106\|UniProtKB=F6TRE5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018181.2\|UniProtKB=H2MVD9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-7320\|UniProtKB=B8A615	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002004.1\|UniProtKB=W5M1Q9	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000011182.2\|UniProtKB=H2M6D3	Oryzias latipes	O
DANRE\|Gene=nefla\|UniProtKB=A0A8M9PUK6	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000014402.2\|UniProtKB=H2MHE7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060312-44\|UniProtKB=Q29RE8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015672.1\|UniProtKB=W5NF82	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000001690.3\|UniProtKB=F6X1H5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000419.3\|UniProtKB=F7BL29	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008941.3\|UniProtKB=F6Q6Q9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006851.3\|UniProtKB=F6ZXN6	Ciona intestinalis	O
BRAFL\|Gene=LOC118403085\|UniProtKB=A0A9J7HCY7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432778\|UniProtKB=A0A9J7MGA0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403058\|UniProtKB=A0A9J7HD97	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432750\|UniProtKB=A0A9J7MHA9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407017\|UniProtKB=A0A9J7HPB0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409117\|UniProtKB=A0A9J7HU07	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432811\|UniProtKB=A0A9J7MHD7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409400\|UniProtKB=A0A9J7HUT1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432844\|UniProtKB=A0A9J7MGA9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432759\|UniProtKB=A0A9J7MFH6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403012\|UniProtKB=A0A9J7HG88	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403038\|UniProtKB=A0A9J7HCU2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432767\|UniProtKB=A0A9J7MFH2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407145\|UniProtKB=A0A9J7HPQ9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407016\|UniProtKB=A0A9J7KKE2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409118\|UniProtKB=A0A9J7KLU4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403049\|UniProtKB=A0A9J7KGA1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409116\|UniProtKB=A0A9J7HUB8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432789\|UniProtKB=A0A9J7MHC7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403069\|UniProtKB=A0A9J7HG61	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423047\|UniProtKB=A0A9J7LRC0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432800\|UniProtKB=A0A9J7MIE9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405940\|UniProtKB=A0A9J7HL95	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403078\|UniProtKB=A0A9J7HD55	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403028\|UniProtKB=A0A9J7HD77	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410434\|UniProtKB=A0A9J7KPZ7	Branchiostoma floridae	O