The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

CLDN5

Organism:

Bos taurus

View Gene in Tree

Tree

Gene Name:

Claudin-5

Gene ID:

ENSBTAG00000022020

Protein ID:

Q2HJ22

Persistent Id:

PTN000243830

Alternate Ids:

ENSBTAP00000029418(Ensembl_PRO)	617453(GeneID)
ENSBTAT00000029418(Ensembl_TRS)	CLDN5(Symbol)
NM_001076460(refSeq)	87578219(GI)
AAI13350(EMBL-CDS)	CLD5_BOVIN(UniProtKB-ID)
BC113349(EMBL)	ENSBTAG00000022020(Ensembl)
CLD5(Synonym)
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PANTHER Classification

PANTHER Family:	CLAUDIN (PTHR12002)
PANTHER Subfamily:	CLAUDIN-5 (PTHR12002:SF35)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cell-cell junction assembly cell adhesion
PANTHER GO-slim Cellular Component:	plasma membrane bicellular tight junction
PANTHER protein class:	tight junction

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	structural molecule activity
GO BP Complete:	bicellular tight junction assembly, cell adhesion
GO CC Complete:	bicellular tight junction, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

-

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2047\|UniProtKB=O00501	Homo sapiens	LDO
MACMU\|Ensembl=ENSMMUG00000060434.1\|UniProtKB=F7CD43	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1276112\|UniProtKB=O54942	Mus musculus	LDO
RAT\|RGD=68431\|UniProtKB=Q9JKD6	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000041667.2\|UniProtKB=C3VML1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000047513.1\|UniProtKB=A0A9L0TDG5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000029093.3\|UniProtKB=M3WYM1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029410.1\|UniProtKB=A0A8I3Q328	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000050792.1\|UniProtKB=A0A5F8GYS5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003574.3\|UniProtKB=F7DGF8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024495.1\|UniProtKB=A0A8V1A002	Gallus gallus	LDO
XENLA\|Gene=cldn5.L\|UniProtKB=Q6PA22	Xenopus laevis	O
XENLA\|Gene=cldn5.S\|UniProtKB=Q6GNW1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-976044\|UniProtKB=F6TD70	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001086.2\|UniProtKB=H2L691	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041010-140\|UniProtKB=F1R5J2	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2442\|UniProtKB=Q6NUZ6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000018139.1\|UniProtKB=W5NNN1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020534.1\|UniProtKB=H2Y1V9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000023118.1\|UniProtKB=H2XNH4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006335.3\|UniProtKB=F6PX91	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000466.3\|UniProtKB=F6YW52	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013927.2\|UniProtKB=F6PQC6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008241.3\|UniProtKB=F6R4U4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000021125.1\|UniProtKB=H2XJV5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018196.1\|UniProtKB=A0A1W5BNS4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009650.3\|UniProtKB=F6WVA9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004592.3\|UniProtKB=F6PSB3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020956.1\|UniProtKB=H2XV98	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_77360\|UniProtKB=C3Z150	Branchiostoma floridae	O