PANTHER Gene Information

Gene Symbol(s):

CLDN5

Organism:

Equus caballus

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Gene Name:

Claudin

Gene ID:

ENSECAG00000047513.1

Protein ID:

A0A9L0TDG5

Persistent Id:

PTN007556585

Alternate Ids:

ENSECAP00000085142(Ensembl_PRO)	ENSECAT00000135454(Ensembl_TRS)
A0A9L0TDG5(Synonym)	ENSECAG00000047513(Ensembl)
A0A9L0TDG5_HORSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	CLAUDIN (PTHR12002)
PANTHER Subfamily:	CLAUDIN-5 (PTHR12002:SF35)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cell-cell junction assembly cell adhesion
PANTHER GO-slim Cellular Component:	plasma membrane bicellular tight junction
PANTHER protein class:	tight junction

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	structural molecule activity
GO BP Complete:	positive regulation of establishment of endothelial barrier, negative regulation of angiogenesis, cell-cell junction assembly, positive regulation of cell population proliferation, transforming growth factor beta receptor signaling pathway, positive regulation of bicellular tight junction assembly, cell adhesion, negative regulation of vascular permeability, negative regulation of gene expression, establishment of blood-retinal barrier, positive regulation of gene expression, bicellular tight junction assembly, tight junction assembly, negative regulation of cell migration, maintenance of blood-brain barrier
GO CC Complete:	apicolateral plasma membrane, bicellular tight junction, tight junction, cell-cell junction, membrane, plasma membrane, cortical actin cytoskeleton

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2047\|UniProtKB=O00501	Homo sapiens	LDO
MACMU\|Ensembl=ENSMMUG00000060434.1\|UniProtKB=F7CD43	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1276112\|UniProtKB=O54942	Mus musculus	LDO
RAT\|RGD=68431\|UniProtKB=Q9JKD6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000022020\|UniProtKB=Q2HJ22	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000041667.2\|UniProtKB=C3VML1	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000029093.3\|UniProtKB=M3WYM1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029410.1\|UniProtKB=A0A8I3Q328	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000050792.1\|UniProtKB=A0A5F8GYS5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003574.3\|UniProtKB=F7DGF8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024495.1\|UniProtKB=A0A8V1A002	Gallus gallus	LDO
XENLA\|Gene=cldn5.L\|UniProtKB=Q6PA22	Xenopus laevis	O
XENLA\|Gene=cldn5.S\|UniProtKB=Q6GNW1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-976044\|UniProtKB=F6TD70	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001086.2\|UniProtKB=H2L691	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041010-140\|UniProtKB=F1R5J2	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2442\|UniProtKB=Q6NUZ6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000018139.1\|UniProtKB=W5NNN1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020534.1\|UniProtKB=H2Y1V9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000023118.1\|UniProtKB=H2XNH4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006335.3\|UniProtKB=F6PX91	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000466.3\|UniProtKB=F6YW52	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013927.2\|UniProtKB=F6PQC6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008241.3\|UniProtKB=F6R4U4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000021125.1\|UniProtKB=H2XJV5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018196.1\|UniProtKB=A0A1W5BNS4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009650.3\|UniProtKB=F6WVA9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004592.3\|UniProtKB=F6PSB3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020956.1\|UniProtKB=H2XV98	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_77360\|UniProtKB=C3Z150	Branchiostoma floridae	O