PANTHER Gene Information

Gene Symbol(s):

AK4

Organism:

Bos taurus

View Gene in Tree

Tree

Gene Name:

Adenylate kinase 4, mitochondrial

Gene ID:

ENSBTAG00000030674

Protein ID:

Q0VCP1

Persistent Id:

PTN000599933

Alternate Ids:

KAD4_BOVIN(UniProtKB-ID)	AK 4 {ECO:0000255\|HAMAP-Rule:MF_03170}(Synonym)
2.7.4.6 {ECO:0000255\|HAMAP-Rule:MF_03170}(EC)	XP_005204514(refSeq)
ENSBTAG00000030674(Ensembl)	118150966(GI)
BC120077(EMBL)	AAI20078(EMBL-CDS)
AK4{ECO:0000255\|HAMAP-Rule:MF_03170}(Symbol)	ENSBTAT00000043366(Ensembl_TRS)
517063(GeneID)	ENSBTAP00000040941(Ensembl_PRO)
Show All

PANTHER Classification

PANTHER Family:	NUCLEOTIDE KINASE (PTHR23359)
PANTHER Subfamily:	ADENYLATE KINASE 4, MITOCHONDRIAL (PTHR23359:SF58)
PANTHER GO-slim Molecular Function:	nucleoside diphosphate kinase activity
PANTHER GO-slim Biological Process:	purine ribonucleoside monophosphate metabolic process purine ribonucleotide metabolic process nucleoside triphosphate biosynthetic process
PANTHER GO-slim Cellular Component:	mitochondrial matrix
PANTHER protein class:	nucleotide kinase

Pathway Categories:

De novo purine biosynthesis

Adenylate kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP binding, CMP kinase activity, adenylate kinase activity, ATP binding, dCMP kinase activity, nucleoside diphosphate kinase activity, (deoxy)adenylate kinase activity, nucleoside triphosphate adenylate kinase activity
GO BP Complete:	ribonucleoside diphosphate biosynthetic process, regulation of oxidative phosphorylation, ADP biosynthetic process, AMP metabolic process, nucleoside triphosphate biosynthetic process, ATP metabolic process, GTP metabolic process, nucleoside monophosphate phosphorylation, cellular response to hypoxia
GO CC Complete:	cytoplasm, mitochondrial matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Interconversion of nucleotide di- and triphosphates, Metabolism of nucleotides, Metabolism

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000047963.1\|UniProtKB=A0A2I3SBZ6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001103.3\|UniProtKB=A0A2I2Z536	Gorilla gorilla gorilla	O
HUMAN\|HGNC=21596\|UniProtKB=A0A8I5KW96	Homo sapiens	O
HUMAN\|HGNC=363\|UniProtKB=P27144	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000827.6\|UniProtKB=H2PZ67	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000043224.1\|UniProtKB=A0A2I2Y7V2	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000026644.2\|UniProtKB=G3SGF3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000030101.3\|UniProtKB=F7GWL3	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000053254.1\|UniProtKB=A0A5F8A696	Macaca mulatta	LDO
MOUSE\|MGI=MGI=87979\|UniProtKB=Q9WUR9	Mus musculus	LDO
RAT\|RGD=2078\|UniProtKB=Q9WUS0	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000040337.3\|UniProtKB=B1NI70	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018332.4\|UniProtKB=F7AWU9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000033540.3\|UniProtKB=A0A2I2V063	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029543.1\|UniProtKB=A0A8I3QJY0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001217.4\|UniProtKB=F7G7R5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009019.2\|UniProtKB=F7EU92	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024132.1\|UniProtKB=A0A8V0ZQU1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008789.4\|UniProtKB=A0A803SYD8	Anolis carolinensis	LDO
XENLA\|Gene=ak4.L\|UniProtKB=A0A1L8GLX1	Xenopus laevis	O
XENLA\|Gene=ak4.S\|UniProtKB=A0A1L8GFP7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-959954\|UniProtKB=A0A803JVY4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009987.2\|UniProtKB=H2M295	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2505\|UniProtKB=Q6NUY0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006837.1\|UniProtKB=W5MIQ9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004751.3\|UniProtKB=F6PR96	Ciona intestinalis	O
BRAFL\|Gene=LOC118431882\|UniProtKB=A0A9J7MDD2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC583479\|UniProtKB=A0A7M6USS0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00009543\|UniProtKB=Q86D11	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG21667\|UniProtKB=A8Y0S6	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00014058\|UniProtKB=Q09629	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026035\|UniProtKB=A8WSS5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00280954\|UniProtKB=A0A2A6BWI5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0042094\|UniProtKB=Q9VGU6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009660\|UniProtKB=A0A1S4H1P5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC009374\|UniProtKB=D6WR14	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_206791\|UniProtKB=E9FWU3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020183\|UniProtKB=B7Q3A0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG114439\|UniProtKB=T1EG17	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g184404\|UniProtKB=A7S170	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21342\|UniProtKB=A9UVJ8	Monosiga brevicollis	O
YEAST\|SGD=S000000972\|UniProtKB=P26364	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR115C\|UniProtKB=Q74ZT3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000185135\|UniProtKB=A0A1D8PQH7	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F26521g\|UniProtKB=Q6C0A1	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00259\|UniProtKB=Q5BGS1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G03420\|UniProtKB=Q4WK78	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03216\|UniProtKB=Q7SGV3	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_06024\|UniProtKB=A7EL27	Sclerotinia sclerotiorum	O
PHANO\|Gene_ORFName=SNOG_07673\|UniProtKB=Q0UKP1	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04669\|UniProtKB=Q0UU95	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CND00160\|UniProtKB=Q5KJ94	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05924\|UniProtKB=A0A0D1CGU1	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_01078\|UniProtKB=E3JUM2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_87801\|UniProtKB=F4P0A1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_29990\|UniProtKB=F4P268	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0292730\|UniProtKB=Q54CT8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_40956\|UniProtKB=F0ZZ46	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_13_1350\|UniProtKB=Q4QG19	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_27_1950\|UniProtKB=E9ADH5	Leishmania major	O
PHYRM\|Gene=H3H479_PHYRM\|UniProtKB=H3H479	Phytophthora ramorum	O
LEIMA\|EnsemblGenome=LMJF_25_2370\|UniProtKB=Q4Q9J9	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.0990\|UniProtKB=Q386G1	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_4849\|UniProtKB=A8BTN6	Giardia intestinalis	O
PLAF7\|EnsemblGenome=PF3D7_0931900\|UniProtKB=C0H582	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00028631001\|UniProtKB=A0BGC9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026987001\|UniProtKB=A0EH72	Paramecium tetraurelia	O
KORCO\|EnsemblGenome=Kcr_1559\|UniProtKB=B1L775	Korarchaeum cryptofilum	O
HALSA\|EnsemblGenome=VNG_1724G\|UniProtKB=Q9HPA7	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0812\|UniProtKB=Q5JH68	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_2957\|UniProtKB=A9WG02	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2390\|UniProtKB=A9WH87	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO4723\|UniProtKB=P43414	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv0733\|UniProtKB=P9WKF5	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO3460\|UniProtKB=A5I7I5	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0210\|UniProtKB=Q8DRD4	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02490\|UniProtKB=Q2FW27	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAD00689\|UniProtKB=Q8Y449	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_01370\|UniProtKB=P16304	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0152\|UniProtKB=Q81J22	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_1479\|UniProtKB=Q9X1I8	Thermotoga maritima	O
GLOVI\|EnsemblGenome=BAC89333\|UniProtKB=Q7NKT5	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA16643\|UniProtKB=P72641	Synechocystis	O
SYNY3\|EnsemblGenome=BAA17330\|UniProtKB=P73302	Synechocystis	O
LEPIN\|EnsemblGenome=LA_0760\|UniProtKB=Q9XD15	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_4387\|UniProtKB=Q89ZJ0	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_128\|UniProtKB=O84130	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB7867\|UniProtKB=Q7UN00	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_078\|UniProtKB=O66490	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1836\|UniProtKB=B5YHP1	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1001\|UniProtKB=B8E1F3	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1298\|UniProtKB=Q8RE31	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_0618\|UniProtKB=P56104	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB0823\|UniProtKB=P0A0U7	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU2836\|UniProtKB=Q749A8	Geobacter sulfurreducens	O
BRADU\|Gene=adk\|UniProtKB=Q89JA5	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0454\|UniProtKB=Q83E75	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0349\|UniProtKB=P24323	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2018\|UniProtKB=Q8EFF5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0986\|UniProtKB=Q9KTB7	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA3686\|UniProtKB=Q9HXV4	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0488\|UniProtKB=P0A1V4	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0812\|UniProtKB=O69172	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76253\|UniProtKB=P69441	Escherichia coli	O