PANTHER Gene Information

Gene Symbol(s):

AK4

Organism:

Equus caballus

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Gene Name:

Adenylate kinase 4, mitochondrial

Gene ID:

ENSECAG00000018332.4

Protein ID:

F7AWU9

Persistent Id:

PTN009071582

Alternate Ids:

ENSECAG00000018332(Ensembl)	F7AWU9(Synonym)
F7AWU9_HORSE(UniProtKB-ID)	ENSECAT00000019552(Ensembl_TRS)
ENSECAP00000016009(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	NUCLEOTIDE KINASE (PTHR23359)
PANTHER Subfamily:	ADENYLATE KINASE 4, MITOCHONDRIAL (PTHR23359:SF58)
PANTHER GO-slim Molecular Function:	nucleoside diphosphate kinase activity
PANTHER GO-slim Biological Process:	purine ribonucleoside monophosphate metabolic process purine ribonucleotide metabolic process nucleoside triphosphate biosynthetic process
PANTHER GO-slim Cellular Component:	mitochondrial matrix
PANTHER protein class:	nucleotide kinase

Pathway Categories:

De novo purine biosynthesis

Adenylate kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	GTP binding, CMP kinase activity, adenylate kinase activity, ATP binding, dCMP kinase activity, nucleoside diphosphate kinase activity, kinase activity, (deoxy)adenylate kinase activity, nucleoside triphosphate adenylate kinase activity
GO BP Complete:	ADP biosynthetic process, AMP metabolic process, nucleoside triphosphate biosynthetic process, ATP metabolic process, GTP metabolic process, nucleoside monophosphate phosphorylation, nucleobase-containing compound metabolic process
GO CC Complete:	cytoplasm, mitochondrial matrix, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000047963.1\|UniProtKB=A0A2I3SBZ6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001103.3\|UniProtKB=A0A2I2Z536	Gorilla gorilla gorilla	O
HUMAN\|HGNC=21596\|UniProtKB=A0A8I5KW96	Homo sapiens	O
HUMAN\|HGNC=363\|UniProtKB=P27144	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000827.6\|UniProtKB=H2PZ67	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000043224.1\|UniProtKB=A0A2I2Y7V2	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000026644.2\|UniProtKB=G3SGF3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000030101.3\|UniProtKB=F7GWL3	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000053254.1\|UniProtKB=A0A5F8A696	Macaca mulatta	LDO
MOUSE\|MGI=MGI=87979\|UniProtKB=Q9WUR9	Mus musculus	LDO
RAT\|RGD=2078\|UniProtKB=Q9WUS0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020774.5\|UniProtKB=A0A3Q1LVZ0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000030674\|UniProtKB=Q0VCP1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000040337.3\|UniProtKB=B1NI70	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000033540.3\|UniProtKB=A0A2I2V063	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029543.1\|UniProtKB=A0A8I3QJY0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001217.4\|UniProtKB=F7G7R5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009019.2\|UniProtKB=F7EU92	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024132.1\|UniProtKB=A0A8V0ZQU1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008789.4\|UniProtKB=A0A803SYD8	Anolis carolinensis	LDO
XENLA\|Gene=ak4.L\|UniProtKB=A0A1L8GLX1	Xenopus laevis	O
XENLA\|Gene=ak4.S\|UniProtKB=A0A1L8GFP7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-959954\|UniProtKB=A0A803JVY4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009987.2\|UniProtKB=H2M295	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2505\|UniProtKB=Q6NUY0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006837.1\|UniProtKB=W5MIQ9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004751.3\|UniProtKB=F6PR96	Ciona intestinalis	O
BRAFL\|Gene=LOC118431882\|UniProtKB=A0A9J7MDD2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC583479\|UniProtKB=A0A7M6USS0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00009543\|UniProtKB=Q86D11	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG21667\|UniProtKB=A8Y0S6	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00014058\|UniProtKB=Q09629	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026035\|UniProtKB=A8WSS5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00280954\|UniProtKB=A0A2A6BWI5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0042094\|UniProtKB=Q9VGU6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009660\|UniProtKB=A0A1S4H1P5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC009374\|UniProtKB=D6WR14	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_206791\|UniProtKB=E9FWU3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020183\|UniProtKB=B7Q3A0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG114439\|UniProtKB=T1EG17	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g184404\|UniProtKB=A7S170	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21342\|UniProtKB=A9UVJ8	Monosiga brevicollis	O
YEAST\|SGD=S000000972\|UniProtKB=P26364	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR115C\|UniProtKB=Q74ZT3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000185135\|UniProtKB=A0A1D8PQH7	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F26521g\|UniProtKB=Q6C0A1	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00259\|UniProtKB=Q5BGS1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G03420\|UniProtKB=Q4WK78	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03216\|UniProtKB=Q7SGV3	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_06024\|UniProtKB=A7EL27	Sclerotinia sclerotiorum	O
PHANO\|Gene_ORFName=SNOG_07673\|UniProtKB=Q0UKP1	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04669\|UniProtKB=Q0UU95	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CND00160\|UniProtKB=Q5KJ94	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05924\|UniProtKB=A0A0D1CGU1	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_01078\|UniProtKB=E3JUM2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_87801\|UniProtKB=F4P0A1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_29990\|UniProtKB=F4P268	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0292730\|UniProtKB=Q54CT8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_40956\|UniProtKB=F0ZZ46	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_13_1350\|UniProtKB=Q4QG19	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_27_1950\|UniProtKB=E9ADH5	Leishmania major	O
PHYRM\|Gene=H3H479_PHYRM\|UniProtKB=H3H479	Phytophthora ramorum	O
LEIMA\|EnsemblGenome=LMJF_25_2370\|UniProtKB=Q4Q9J9	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.0990\|UniProtKB=Q386G1	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_4849\|UniProtKB=A8BTN6	Giardia intestinalis	O
PLAF7\|EnsemblGenome=PF3D7_0931900\|UniProtKB=C0H582	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00028631001\|UniProtKB=A0BGC9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026987001\|UniProtKB=A0EH72	Paramecium tetraurelia	O
KORCO\|EnsemblGenome=Kcr_1559\|UniProtKB=B1L775	Korarchaeum cryptofilum	O
HALSA\|EnsemblGenome=VNG_1724G\|UniProtKB=Q9HPA7	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0812\|UniProtKB=Q5JH68	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_2957\|UniProtKB=A9WG02	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2390\|UniProtKB=A9WH87	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO4723\|UniProtKB=P43414	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv0733\|UniProtKB=P9WKF5	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO3460\|UniProtKB=A5I7I5	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0210\|UniProtKB=Q8DRD4	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02490\|UniProtKB=Q2FW27	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAD00689\|UniProtKB=Q8Y449	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_01370\|UniProtKB=P16304	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0152\|UniProtKB=Q81J22	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_1479\|UniProtKB=Q9X1I8	Thermotoga maritima	O
GLOVI\|EnsemblGenome=BAC89333\|UniProtKB=Q7NKT5	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA16643\|UniProtKB=P72641	Synechocystis	O
SYNY3\|EnsemblGenome=BAA17330\|UniProtKB=P73302	Synechocystis	O
LEPIN\|EnsemblGenome=LA_0760\|UniProtKB=Q9XD15	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_4387\|UniProtKB=Q89ZJ0	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_128\|UniProtKB=O84130	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB7867\|UniProtKB=Q7UN00	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_078\|UniProtKB=O66490	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1836\|UniProtKB=B5YHP1	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1001\|UniProtKB=B8E1F3	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1298\|UniProtKB=Q8RE31	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_0618\|UniProtKB=P56104	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB0823\|UniProtKB=P0A0U7	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU2836\|UniProtKB=Q749A8	Geobacter sulfurreducens	O
BRADU\|Gene=adk\|UniProtKB=Q89JA5	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0454\|UniProtKB=Q83E75	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0349\|UniProtKB=P24323	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2018\|UniProtKB=Q8EFF5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0986\|UniProtKB=Q9KTB7	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA3686\|UniProtKB=Q9HXV4	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0488\|UniProtKB=P0A1V4	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0812\|UniProtKB=O69172	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76253\|UniProtKB=P69441	Escherichia coli	O