PANTHER Gene Information   
Gene Symbol(s):
Organism: Bos taurus
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Gene Name: EF-hand domain-containing protein
Gene ID: ENSBTAG00000031483.3
Protein ID: A0A3Q1MR28
Persistent Id: PTN007727243
Alternate Ids:
A0A3Q1MR28_BOVIN(UniProtKB-ID) ENSBTAP00000074130(Ensembl_PRO)
ENSBTAT00000044622(Ensembl_TRS) ENSBTAG00000031483(Ensembl)
A0A3Q1MR28(Synonym)
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PANTHER Classification
PANTHER Family: CALCIUM BINDING PROTEIN (PTHR23050)
PANTHER Subfamily: CALMODULIN-1 (PTHR23050:SF531)  
PANTHER GO-slim Molecular Function: calcium ion binding
PANTHER GO-slim Biological Process: positive regulation of cation channel activity
regulation of release of sequestered calcium ion into cytosol
PANTHER GO-slim Cellular Component: nucleus
centrosome
cytoplasm
PANTHER protein class: calmodulin-related
Pathway Categories: CCKR signaling map
   CaM
B cell activation
   Calmodulin
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   Calmodulin
T cell activation
   Calmodulin
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Phosphorylase b kinase

GO MF Complete: calcium ion binding
GO BP Complete: -
GO CC Complete: centrosome, myelin sheath, cytoplasm
Reactome Pathways: Platelet calcium homeostasis, Ionotropic activity of kainate receptors, Adaptive Immune System, Post-translational protein modification, Activation of Ca-permeable Kainate Receptor, Stimuli-sensing channels, Intracellular signaling by second messengers, Platelet activation, signaling and aggregation, Signal Transduction, Activation of NMDA receptors and postsynaptic events, Response to elevated platelet cytosolic Ca2+, Metabolism, RAS processing, Innate Immune System, eNOS activation, Hemostasis, Glycogen breakdown (glycogenolysis), CaM pathway, Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Ca-dependent events, G-protein mediated events, Glycogen metabolism, PLC beta mediated events, RHO GTPase Effectors, RAF/MAP kinase cascade, RAF activation, Protein methylation, Smooth Muscle Contraction, G alpha (i) signalling events, SLC-mediated transmembrane transport, Metabolism of cofactors, Phase 0 - rapid depolarisation, Post NMDA receptor activation events, Cardiac conduction, Sodium/Calcium exchangers, Cam-PDE 1 activation, C-type lectin receptors (CLRs), Immune System, Ca2+ pathway, GPCR downstream signalling, Inositol phosphate metabolism, DAG and IP3 signaling, Extra-nuclear estrogen signaling, The phototransduction cascade, MAPK1/MAPK3 signaling, Opioid Signalling, Inactivation, recovery and regulation of the phototransduction cascade, Ion transport by P-type ATPases, Unblocking of NMDA receptors, glutamate binding and activation, VEGFA-VEGFR2 Pathway, Muscle contraction, Metabolism of vitamins and cofactors, Reduction of cytosolic Ca++ levels, Signaling by WNT, Signaling by Rho GTPases, Activation of kainate receptors upon glutamate binding, Beta-catenin independent WNT signaling, Ion channel transport, RHO GTPases activate PAKs, FCERI mediated Ca+2 mobilization, Signaling by the B Cell Receptor (BCR), PKA-mediated phosphorylation of CREB, CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde, Activation of RAC1 downstream of NMDARs, Transport of inorganic cations/anions and amino acids/oligopeptides, Platelet homeostasis, Signaling by Nuclear Receptors, Signaling by Receptor Tyrosine Kinases, Metabolism of nitric oxide: NOS3 activation and regulation, VEGFR2 mediated vascular permeability, Metabolism of proteins, Calmodulin induced events, Platelet degranulation , Sensory Perception, CaMK IV-mediated phosphorylation of CREB, Ion homeostasis, Downstream signaling events of B Cell Receptor (BCR), Transport of small molecules, Synthesis of IP3 and IP4 in the cytosol, MAPK family signaling cascades, CLEC7A (Dectin-1) signaling, Signaling by GPCR, Metabolism of carbohydrates, ESR-mediated signaling, PKA activation, Transmission across Chemical Synapses, Calcineurin activates NFAT, Neuronal System, RHO GTPases activate IQGAPs, CLEC7A (Dectin-1) induces NFAT activation, Neurotransmitter receptors and postsynaptic signal transmission, Fc epsilon receptor (FCERI) signaling, Signaling by VEGF, Visual phototransduction