PANTHER Gene Information   
Gene Symbol(s): Calm1
Organism: Mus musculus
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Gene Name: Calmodulin-1
Gene ID: MGI:88251
Protein ID: P0DP26
Persistent Id: PTN004596950
Alternate Ids:
BAB23462(EMBL-CDS) 74181513(GI)
CALM1(Synonym) AK160057(EMBL)
CHEMBL3562176(ChEMBL) ENSMUST00000110082(Ensembl_TRS)
12313(GeneID) ENSMUSP00000105709(Ensembl_PRO)
Q3U6Z5(AltAccession) NM_009790(refSeq)
MGI:88251(MGI) CALM1_MOUSE(UniProtKB-ID)
ENSMUSG00000036438(Ensembl)
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PANTHER Classification
PANTHER Family: CALCIUM BINDING PROTEIN (PTHR23050)
PANTHER Subfamily: CALMODULIN-1 (PTHR23050:SF531)  
PANTHER GO-slim Molecular Function: calcium ion binding
PANTHER GO-slim Biological Process: positive regulation of cation channel activity
regulation of release of sequestered calcium ion into cytosol
PANTHER GO-slim Cellular Component: nucleus
centrosome
cytoplasm
PANTHER protein class: calmodulin-related
Pathway Categories: CCKR signaling map
   CaM
B cell activation
   Calmodulin
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   Calmodulin
T cell activation
   Calmodulin
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Phosphorylase b kinase

GO MF Complete: protein kinase binding, phosphatidylinositol 3-kinase binding, protein domain specific binding, protein serine/threonine kinase activator activity, calcium-dependent protein binding, adenylate cyclase binding, transmembrane transporter binding, type 3 metabotropic glutamate receptor binding, protein binding, adenylate cyclase activator activity, protein phosphatase activator activity, calcium ion binding, titin binding, nitric-oxide synthase regulator activity, nitric-oxide synthase binding, calcium channel inhibitor activity
GO BP Complete: regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, positive regulation of ryanodine-sensitive calcium-release channel activity, negative regulation of high voltage-gated calcium channel activity, positive regulation of DNA binding, regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of receptor signaling pathway via JAK-STAT, negative regulation of ryanodine-sensitive calcium-release channel activity, regulation of heart rate, detection of calcium ion, positive regulation of cyclic-nucleotide phosphodiesterase activity, G2/M transition of mitotic cell cycle, calcineurin-mediated signaling, presynaptic endocytosis, mitochondrion-endoplasmic reticulum membrane tethering, response to calcium ion, autophagosome membrane docking, regulation of cytokinesis, cellular response to type II interferon, regulation of cardiac muscle cell action potential, regulation of cardiac muscle contraction, organelle localization by membrane tethering, cellular response to interferon-beta
GO CC Complete: catalytic complex, myelin sheath, voltage-gated potassium channel complex, spindle pole, nucleoplasm, calyx of Held, growth cone, spindle microtubule, centrosome, mitochondrial membrane, calcium channel complex, sperm midpiece, cytoplasm, cytosol, protein-containing complex, synaptic vesicle membrane, sarcomere
Reactome Pathways: Signaling by Receptor Tyrosine Kinases, Immune System, Smooth Muscle Contraction, Protein methylation, GPCR downstream signalling, VEGFA-VEGFR2 Pathway, VEGFR2 mediated vascular permeability, FCERI mediated Ca+2 mobilization, CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde, Signaling by Nuclear Receptors, Unblocking of NMDA receptors, glutamate binding and activation, RAF/MAP kinase cascade, Signaling by the B Cell Receptor (BCR), Post NMDA receptor activation events, RAF activation, Calcineurin activates NFAT, RHO GTPases activate IQGAPs, Activation of kainate receptors upon glutamate binding, Ion transport by P-type ATPases, Opioid Signalling, Metabolism of nitric oxide: NOS3 activation and regulation, Signaling by WNT, Metabolism of vitamins and cofactors, Signaling by Rho GTPases, Visual phototransduction, Innate Immune System, Signal Transduction, Beta-catenin independent WNT signaling, Platelet homeostasis, G-protein mediated events, Activation of NMDA receptors and postsynaptic events, Glycogen metabolism, Transport of inorganic cations/anions and amino acids/oligopeptides, Ca-dependent events, CaM pathway, RHO GTPases activate PAKs, Fc epsilon receptor (FCERI) signaling, Cam-PDE 1 activation, Synthesis of IP3 and IP4 in the cytosol, PLC beta mediated events, Downstream signaling events of B Cell Receptor (BCR), Ion homeostasis, Sensory Perception, Adaptive Immune System, MAPK family signaling cascades, Post-translational protein modification, Transport of small molecules, Cardiac conduction, G alpha (i) signalling events, Reduction of cytosolic Ca++ levels, Metabolism of cofactors, RHO GTPase Effectors, SLC-mediated transmembrane transport, Transmission across Chemical Synapses, Muscle contraction, ESR-mediated signaling, Extra-nuclear estrogen signaling, Neuronal System, Sodium/Calcium exchangers, CLEC7A (Dectin-1) signaling, Metabolism of carbohydrates, Activation of RAC1 downstream of NMDARs, CLEC7A (Dectin-1) induces NFAT activation, MAPK1/MAPK3 signaling, DAG and IP3 signaling, Signaling by GPCR, Inositol phosphate metabolism, Ionotropic activity of kainate receptors, Neurotransmitter receptors and postsynaptic signal transmission, RAS processing, Activation of Ca-permeable Kainate Receptor, Stimuli-sensing channels, Signaling by VEGF, Ion channel transport, Intracellular signaling by second messengers, eNOS activation, PKA activation, Platelet calcium homeostasis, CaMK IV-mediated phosphorylation of CREB, Calmodulin induced events, C-type lectin receptors (CLRs), PKA-mediated phosphorylation of CREB, The phototransduction cascade, Response to elevated platelet cytosolic Ca2+, Platelet activation, signaling and aggregation, Glycogen breakdown (glycogenolysis), Platelet degranulation , Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Hemostasis, Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, Inactivation, recovery and regulation of the phototransduction cascade, Metabolism, Ca2+ pathway, Metabolism of proteins