PANTHER Gene Information   
Gene Symbol(s): SHMT2
Organism: Bos taurus
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Gene Name: Serine hydroxymethyltransferase, mitochondrial
Gene ID: ENSBTAG00000031500
Protein ID: Q3SZ20
Persistent Id: PTN000188091
Alternate Ids:
507197(GeneID) NM_001034282(refSeq)
SHMT2(Symbol) SHMT(Synonym)
BC103242(EMBL) ENSBTAT00000038244(Ensembl_TRS)
ENSBTAG00000031500(Ensembl) AAI03243(EMBL-CDS)
2.1.2.1 {ECO:0000250|UniProtKB:P34897}(EC) 108935997(GI)
GLYM_BOVIN(UniProtKB-ID) ENSBTAP00000038059(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: SERINE HYDROXYMETHYLTRANSFERASE (PTHR11680)
PANTHER Subfamily: SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL (PTHR11680:SF28)  
PANTHER GO-slim Molecular Function: anion binding
heterocyclic compound binding
organic cyclic compound binding
transferase activity, transferring one-carbon groups
PANTHER GO-slim Biological Process: proteinogenic amino acid biosynthetic process
folic acid-containing compound metabolic process
L-amino acid biosynthetic process
PANTHER GO-slim Cellular Component: mitochondrion
PANTHER protein class: methyltransferase
Pathway Categories: Serine glycine biosynthesis
   Glycine hydroxymethyltransferase

GO MF Complete: pyridoxal phosphate binding, identical protein binding, glycine hydroxymethyltransferase activity, chromatin binding
GO BP Complete: regulation of oxidative phosphorylation, response to type I interferon, L-serine metabolic process, tetrahydrofolate metabolic process, regulation of aerobic respiration, one-carbon metabolic process, glycine metabolic process, protein homotetramerization, protein tetramerization, glycine biosynthetic process from serine, tetrahydrofolate interconversion, regulation of mitochondrial translation, protein K63-linked deubiquitination
GO CC Complete: nucleus, microtubule cytoskeleton, cytoplasm, mitochondrial matrix, BRISC complex, mitochondrion, mitochondrial inner membrane, mitochondrial nucleoid
Reactome Pathways: RHO GTPase cycle, Metabolism of water-soluble vitamins and cofactors, Metabolism of proteins, RHOG GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Metabolism of folate and pterines, Signal Transduction, Mitochondrial protein degradation, Metabolism, Metabolism of vitamins and cofactors, Signaling by Rho GTPases