PANTHER Gene Information

Gene Symbol(s):

LOC107906992

Organism:

Gossypium hirsutum

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Tree

Gene Name:

Serine hydroxymethyltransferase

Gene ID:

LOC107906992

Protein ID:

A0A1U8JLT3

Persistent Id:

PTN004288430

Alternate Ids:

107906992(GeneID)	XP_016689658(refSeq)
1029051991(GI)	A0A1U8JLT3_GOSHI(UniProtKB-ID)
A0A1U8JLT3(Synonym)
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PANTHER Classification

PANTHER Family:	SERINE HYDROXYMETHYLTRANSFERASE (PTHR11680)
PANTHER Subfamily:	SERINE HYDROXYMETHYLTRANSFERASE 3, CHLOROPLASTIC (PTHR11680:SF63)
PANTHER GO-slim Molecular Function:	anion binding heterocyclic compound binding organic cyclic compound binding transferase activity, transferring one-carbon groups
PANTHER GO-slim Biological Process:	proteinogenic amino acid biosynthetic process folic acid-containing compound metabolic process L-amino acid biosynthetic process
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	methyltransferase

Pathway Categories:

Serine glycine biosynthesis

Glycine hydroxymethyltransferase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	pyridoxal phosphate binding, glycine hydroxymethyltransferase activity, transferase activity
GO BP Complete:	glycine biosynthetic process from serine, tetrahydrofolate interconversion, tetrahydrofolate metabolic process, one-carbon metabolic process
GO CC Complete:	cytoplasm, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10850\|UniProtKB=P34896	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000008851.6\|UniProtKB=A0A2I3SI33	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000003097.3\|UniProtKB=A0A2I2Y685	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013535.4\|UniProtKB=F7FV99	Macaca mulatta	O
MOUSE\|MGI=MGI=98299\|UniProtKB=P50431	Mus musculus	O
RAT\|RGD=1312011\|UniProtKB=A0A8I5ZKU9	Rattus norvegicus	O
BOVIN\|Gene=SHMT1\|UniProtKB=Q5E9P9	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000017094.6\|UniProtKB=A0A140T896	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000036208.3\|UniProtKB=A0A286ZN35	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015690.4\|UniProtKB=A0A9L0TGS9	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015421.5\|UniProtKB=M3WMK4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020125.1\|UniProtKB=A0A8I3S1J1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000013682.3\|UniProtKB=A0A5F8HF15	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009875.4\|UniProtKB=K7EA77	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010017745.1\|UniProtKB=A0A8V0YWC0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009076.4\|UniProtKB=A0A803SMI7	Anolis carolinensis	O
XENLA\|Gene=shmt1.L\|UniProtKB=Q8AVC0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-966676\|UniProtKB=Q28CF2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013776.2\|UniProtKB=H2MFA3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1558\|UniProtKB=Q7SXN1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004890.1\|UniProtKB=W5MBX6	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008186.3\|UniProtKB=H2XJF4	Ciona intestinalis	O
BRAFL\|Gene=LOC118403214\|UniProtKB=A0A9J7HGX6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC593509\|UniProtKB=A0A7M7RHP8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003214\|UniProtKB=P50432	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038848\|UniProtKB=Q60V73	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00093558\|UniProtKB=A0A2A6CDH5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0029823\|UniProtKB=Q9W457	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001065\|UniProtKB=F5HM13	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC015993\|UniProtKB=D6WYC6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_301155\|UniProtKB=E9HGN2	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW004246\|UniProtKB=B7PGD5	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG95979\|UniProtKB=T1G995	helobdella robusta	O
HUMAN\|HGNC=10852\|UniProtKB=P34897	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005124.6\|UniProtKB=K7BCQ7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010240.3\|UniProtKB=G3R410	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000021785.4\|UniProtKB=H9ES01	Macaca mulatta	O
MOUSE\|MGI=MGI=1277989\|UniProtKB=Q9CZN7	Mus musculus	O
RAT\|RGD=1308582\|UniProtKB=Q5U3Z7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000031500\|UniProtKB=Q3SZ20	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037077.3\|UniProtKB=A0A287BKR2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021295.4\|UniProtKB=A0A9L0S7X4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000188.6\|UniProtKB=M3VU92	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010365.1\|UniProtKB=A0A8I3N480	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000047243.1\|UniProtKB=A0A6I8P6H1	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000006283.4\|UniProtKB=H9GB95	Anolis carolinensis	O
XENLA\|Gene=shmt2.L\|UniProtKB=Q6AXB3	Xenopus laevis	O
XENLA\|Gene=shmt2.S\|UniProtKB=A0A1L8H9S2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-957476\|UniProtKB=Q68EQ3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000003837.2\|UniProtKB=H2LFQ0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000005536.2\|UniProtKB=H2LLQ5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-071213-1\|UniProtKB=A9LDD9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006059.1\|UniProtKB=W5MG14	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006653.3\|UniProtKB=A0A140TAT7	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_285686\|UniProtKB=C3Y126	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC754129\|UniProtKB=A0A7M7N0V9	Strongylocentrotus purpuratus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_52799\|UniProtKB=E9GMU1	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW017568\|UniProtKB=B7PG87	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g184037\|UniProtKB=A7S060	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG20682\|UniProtKB=B3RMG8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53932\|UniProtKB=B3RMF1	Trichoplax adhaerens	O
YEAST\|SGD=S000004048\|UniProtKB=P37291	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR215C\|UniProtKB=Q75BQ6	Eremothecium gossypii	O
CANAL\|CGD=CAL0000189123\|UniProtKB=O13426	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E16346g\|UniProtKB=Q6C5P5	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03058\|UniProtKB=C8VIR5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G09320\|UniProtKB=Q4WXF4	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02274\|UniProtKB=P34898	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_11816\|UniProtKB=A7F3H0	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12110\|UniProtKB=Q0U804	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC18G6.04c\|UniProtKB=Q10104	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03914\|UniProtKB=B6K5E0	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC24C9.12c\|UniProtKB=O13972	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01766\|UniProtKB=B6JYU6	Schizosaccharomyces japonicus	O
YEAST\|SGD=S000000467\|UniProtKB=P37292	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL188W\|UniProtKB=Q758F0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000174200\|UniProtKB=A0A1D8PRB3	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D22484g\|UniProtKB=Q6C859	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_10745\|UniProtKB=C8V028	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G07810\|UniProtKB=Q4X237	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU05805\|UniProtKB=Q7S5N8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03729\|UniProtKB=A7EEI9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02898\|UniProtKB=Q0UZB6	Phaeosphaeria nodorum	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15526\|UniProtKB=F4NRQ7	Batrachochytrium dendrobatidis	O
PARTE\|EnsemblGenome=GSPATT00037825001\|UniProtKB=A0CF19	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030051001\|UniProtKB=A0BLK1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036300001\|UniProtKB=A0C8P8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031323001\|UniProtKB=A0BRC5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPS_269942\|UniProtKB=B5YLQ7	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G967_PHYRM\|UniProtKB=H3G967	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_09g411900v5\|UniProtKB=A8J4R9	Chlamydomonas reinhardtii	O
MUSAM\|EnsemblGenome=Ma10_g21260\|UniProtKB=A0A804KYN8	Musa acuminata subsp. malaccensis	O
NELNU\|Gene=LOC104587242\|UniProtKB=A0A1U7YS75	Nelumbo nucifera	O
SPIOL\|Gene=LOC110780244\|UniProtKB=A0A9R0I0E1	Spinacia oleracea	O
SPIOL\|Gene=LOC110789254\|UniProtKB=A0A9R0JWX5	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr15g0685531\|UniProtKB=A0A9K3DZ94	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0799381\|UniProtKB=A0A9K3DIA7	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300110930\|UniProtKB=A0A9R1W4T7	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C500286570\|UniProtKB=A0A9R1VMJ1	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a004404mg\|UniProtKB=A0A022PVE7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_21456\|UniProtKB=A0A1U8DRR7	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400002200\|UniProtKB=M0ZQ61	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g065490.3\|UniProtKB=A0A3Q7HN29	Solanum lycopersicum	O
TOBAC\|Gene=LOC107799799\|UniProtKB=A0A1S4APM0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107759094\|UniProtKB=A0A1S3WXP0	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_31045\|UniProtKB=A0A2G2YA60	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400029389\|UniProtKB=M1CVE4	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc12g095930.2\|UniProtKB=A0A3Q7JDH2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107824466\|UniProtKB=A0A1S4CZX6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107779841\|UniProtKB=A0A1S3YUC2	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi04g00063\|UniProtKB=D7STM0	Vitis vinifera	O
BRANA\|Gene_ORFName=DARMORV10_C03P87320.1\|UniProtKB=A0A078HRG0	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00021914001\|UniProtKB=A0A078GFC4	Brassica napus	O
BRACM\|EnsemblGenome=Bra040080\|UniProtKB=M4FG55	Brassica campestris	O
ARATH\|TAIR=locus=2127806\|UniProtKB=Q94JQ3	Arabidopsis thaliana	O
THECC\|EnsemblGenome=TCM_037262\|UniProtKB=A0A061GJ11	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g009680mg\|UniProtKB=A0A067DVM9	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_006G232300v3\|UniProtKB=B9HDQ7	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_16G078300\|UniProtKB=A0A2C9U9Y1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1657030\|UniProtKB=B9S1D7	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_13G222300\|UniProtKB=C6ZJY9	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g073580\|UniProtKB=A0A072VKX5	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_7g108420\|UniProtKB=G7KRT7	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_2g018290\|UniProtKB=G7ILW0	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr12_07640\|UniProtKB=A0A2I4ET63	Juglans regia	O
JUGRE\|EnsemblGenome=Jr07_29400\|UniProtKB=A0A2I4G5I6	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G062380\|UniProtKB=A0A0A0KYS6	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G165800\|UniProtKB=M5WUH7	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_8G013000\|UniProtKB=M5VKY8	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_234535\|UniProtKB=D8SM70	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_232016\|UniProtKB=D8RPG2	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c13_1080\|UniProtKB=A0A2K1JKC8	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0015s0052\|UniProtKB=A0A2R6XGK5	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000570140\|UniProtKB=A0A0U9HIB8	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1793\|UniProtKB=A9A3Y9	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0992\|UniProtKB=B1L5K9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0530\|UniProtKB=Q9UWT5	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0798\|UniProtKB=Q8ZYF9	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3520\|UniProtKB=Q8TK94	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_1597\|UniProtKB=Q58992	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1414G\|UniProtKB=Q9HPY5	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0528\|UniProtKB=Q5JF06	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_2543\|UniProtKB=A9WI58	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5364\|UniProtKB=Q9K4E0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4837\|UniProtKB=Q9KZA9	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO5470\|UniProtKB=O86565	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1093\|UniProtKB=P9WGI9	Mycobacterium tuberculosis	O
MYCTU\|Gene_OrderedLocusName=Rv0070c\|UniProtKB=P9WGI7	Mycobacterium tuberculosis	O
MYCGE\|EnsemblGenome=MG_394\|UniProtKB=P47634	mycoplasma genitalium	O
CLOBH\|Gene_OrderedLocusName=CBO2595\|UniProtKB=A5I526	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0928\|UniProtKB=Q8DPZ0	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02354\|UniProtKB=Q2FWE5	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAD00617\|UniProtKB=Q8Y4B2	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_36900\|UniProtKB=P39148	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_5316\|UniProtKB=Q814V2	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0720\|UniProtKB=Q9WZH9	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0038\|UniProtKB=Q9RYB2	Deinococcus radiodurans	O
GLOVI\|EnsemblGenome=BAC92310\|UniProtKB=Q7ND67	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA17124\|UniProtKB=P77962	Synechocystis	O
LEPIN\|EnsemblGenome=LA_1409\|UniProtKB=Q8F6A0	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_0738\|UniProtKB=Q8A9S7	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_432\|UniProtKB=O84439	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB6215\|UniProtKB=Q7UQN2	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_479\|UniProtKB=O66776	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1387\|UniProtKB=B5YFZ0	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_0810\|UniProtKB=B8E008	Dictyoglomus turgidum	O
BRADU\|EnsemblGenome=BAC50298\|UniProtKB=P24060	Bradyrhizobium diazoefficiens	O
VIBCH\|EnsemblGenome=VC_A0278\|UniProtKB=Q9KMP4	Vibrio cholerae	O
HELPY\|EnsemblGenome=HP_0183\|UniProtKB=P56089	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB1055\|UniProtKB=P56990	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU1607\|UniProtKB=Q74CR5	Geobacter sulfurreducens	O
BRADU\|Gene=glyA\|UniProtKB=Q89HS7	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1419\|UniProtKB=Q83BT3	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0889\|UniProtKB=P43844	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_3471\|UniProtKB=Q8EBN8	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0941\|UniProtKB=Q9KTG1	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0690\|UniProtKB=Q8PCN4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA5415\|UniProtKB=Q9HTE9	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA2444\|UniProtKB=Q9I138	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA4602\|UniProtKB=Q9HVI7	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2555\|UniProtKB=P0A2E1	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_2548\|UniProtKB=Q8ZCR1	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16459\|UniProtKB=P0A825	Escherichia coli	O