PANTHER Gene Information   
Gene Symbol(s):
Organism: Bos taurus
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Gene Name: Histone H4
Gene ID: ENSBTAG00000052609
Protein ID: P62803
Persistent Id: PTN001627516
Alternate Ids:
ENSBTAP00000053034(Ensembl_PRO) XP_874074(refSeq)
280691(GeneID) 27806945(GI)
H4_BOVIN(UniProtKB-ID) AAC39176(EMBL-CDS)
ENSBTAT00000068837(Ensembl_TRS) AF001288(EMBL)
ENSBTAG00000052332(Ensembl) H4.1(Synonym)
P02305(AltAccession)
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PANTHER Classification
PANTHER Family: HISTONE H4 (PTHR10484)
PANTHER Subfamily: HISTONE H4 (PTHR10484:SF210)  
PANTHER GO-slim Molecular Function: DNA binding
PANTHER GO-slim Biological Process: nucleosome assembly
PANTHER GO-slim Cellular Component:
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, structural constituent of chromatin, protein heterodimerization activity
GO BP Complete: nucleosome assembly
GO CC Complete: nucleosome, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, Inhibition of DNA recombination at telomere, Assembly of the ORC complex at the origin of replication, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), Post-translational protein modification, Base-Excision Repair, AP Site Formation, Depurination, RNA Polymerase I Promoter Opening, Processing of DNA double-strand break ends, DNA Double Strand Break Response, Epigenetic regulation of gene expression, Chromatin organization, Signal Transduction, Chromosome Maintenance, SIRT1 negatively regulates rRNA expression, G2/M DNA damage checkpoint, DNA Repair, HATs acetylate histones, RNA Polymerase I Promoter Escape, Cell Cycle, Mitotic, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Deposition of new CENPA-containing nucleosomes at the centromere, Nonhomologous End-Joining (NHEJ), Condensation of Prophase Chromosomes, Assembly of the pre-replicative complex, RHO GTPase Effectors, B-WICH complex positively regulates rRNA expression, DNA Double-Strand Break Repair, SUMO E3 ligases SUMOylate target proteins, Generic Transcription Pathway, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function, Cellular responses to stimuli, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Homology Directed Repair, RNA Polymerase II Transcription, HDMs demethylate histones, PKMTs methylate histone lysines, RNA Polymerase I Promoter Clearance, Transcriptional regulation by small RNAs, DNA Replication Pre-Initiation, G2/M Checkpoints, Mitotic Prophase, Positive epigenetic regulation of rRNA expression, Signaling by WNT, Signaling by Rho GTPases, Gene expression (Transcription), PRC2 methylates histones and DNA, RNA Polymerase I Transcription, NoRC negatively regulates rRNA expression, Cell Cycle, Negative epigenetic regulation of rRNA expression, M Phase, Packaging Of Telomere Ends, Telomere Maintenance, Nucleosome assembly, Chromatin modifying enzymes, Signaling by Nuclear Receptors, TCF dependent signaling in response to WNT, Metabolism of proteins, SUMOylation of chromatin organization proteins, Estrogen-dependent gene expression, Gene Silencing by RNA, Oxidative Stress Induced Senescence, RHO GTPases activate PKNs, Senescence-Associated Secretory Phenotype (SASP), Formation of the beta-catenin:TCF transactivating complex, Cellular responses to stress, SUMOylation, HDACs deacetylate histones, Recognition and association of DNA glycosylase with site containing an affected purine, Base Excision Repair, RMTs methylate histone arginines, ESR-mediated signaling, Cleavage of the damaged purine, Cellular Senescence, Transcriptional regulation by RUNX1, DNA Damage/Telomere Stress Induced Senescence, DNA Replication, Cell Cycle Checkpoints

Orthologs