PANTHER Gene Information   
Gene Symbol(s): H4C16
Organism: Canis lupus familiaris
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Gene Name: Histone H4
Gene ID: ENSCAFG00845025757.1
Protein ID: F2Z4N2
Persistent Id: PTN001627582
Alternate Ids:
ENSCAFP00845022121(Ensembl_PRO) ENSCAFG00845015936(Ensembl)
ENSCAFT00845044879(Ensembl_TRS) 486670(GeneID)
928181355(GI) F2Z4N2(Synonym)
XP_013966113(refSeq) F2Z4N2_CANLF(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: HISTONE H4 (PTHR10484)
PANTHER Subfamily: HISTONE H4 (PTHR10484:SF210)  
PANTHER GO-slim Molecular Function: DNA binding
PANTHER GO-slim Biological Process: nucleosome assembly
PANTHER GO-slim Cellular Component:
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, structural constituent of chromatin, protein heterodimerization activity
GO BP Complete: nucleosome assembly
GO CC Complete: nucleus, nucleosome
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Transcriptional regulation by small RNAs, RHO GTPases activate PKNs, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function, Positive epigenetic regulation of rRNA expression, SIRT1 negatively regulates rRNA expression, Epigenetic regulation of gene expression, RNA Polymerase I Transcription, Assembly of the pre-replicative complex, G2/M DNA damage checkpoint, Cell Cycle, Mitotic, Recognition and association of DNA glycosylase with site containing an affected purine, Cleavage of the damaged purine, Gene expression (Transcription), Gene Silencing by RNA, Condensation of Prophase Chromosomes, B-WICH complex positively regulates rRNA expression, Chromatin modifying enzymes, Signal Transduction, Deposition of new CENPA-containing nucleosomes at the centromere, DNA Replication, Cellular responses to stimuli, HDMs demethylate histones, Assembly of the ORC complex at the origin of replication, PKMTs methylate histone lysines, HATs acetylate histones, Cell Cycle Checkpoints, PRC2 methylates histones and DNA, HDACs deacetylate histones, NoRC negatively regulates rRNA expression, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Nonhomologous End-Joining (NHEJ), Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Base Excision Repair, DNA Double-Strand Break Repair, Signaling by Nuclear Receptors, Inhibition of DNA recombination at telomere, Signaling by Rho GTPases, Chromosome Maintenance, RNA Polymerase I Promoter Opening, Chromatin organization, Oxidative Stress Induced Senescence, Base-Excision Repair, AP Site Formation, Senescence-Associated Secretory Phenotype (SASP), Estrogen-dependent gene expression, Depurination, Cellular Senescence, M Phase, RMTs methylate histone arginines, ESR-mediated signaling, Negative epigenetic regulation of rRNA expression, Generic Transcription Pathway, Transcriptional regulation by RUNX1, DNA Damage/Telomere Stress Induced Senescence, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, DNA Repair, RNA Polymerase I Promoter Escape, RNA Polymerase I Promoter Clearance, RHO GTPase Effectors, DNA Double Strand Break Response, RNA Polymerase II Transcription, G2/M Checkpoints, Nucleosome assembly, Mitotic Prophase, DNA Replication Pre-Initiation, Telomere Maintenance, Cell Cycle, Cellular responses to stress

Orthologs