PANTHER Gene Information   
Gene Symbol(s): SLC11A1
Organism: Bos taurus
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Gene Name: Natural resistance-associated macrophage protein 1
Gene ID: SLC11A1
Protein ID: Q27981
Persistent Id: PTN000194451
Alternate Ids:
27807177(GI) NP_777077(refSeq)
Solute carrier family 11 member 1(Synonym) 282470(GeneID)
AAA82582(EMBL-CDS) U12862(EMBL)
NRAM1_BOVIN(UniProtKB-ID) SLC11A1(Symbol)
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PANTHER Classification
PANTHER Family: SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER (PTHR11706)
PANTHER Subfamily: NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 1 (PTHR11706:SF52)  
PANTHER GO-slim Molecular Function: metal cation:proton antiporter activity
PANTHER GO-slim Biological Process: iron ion transmembrane transport
PANTHER GO-slim Cellular Component: lysosomal membrane
endosome membrane
plasma membrane
phagocytic vesicle
PANTHER protein class: secondary carrier transporter
Pathway Categories: No pathway information available
GO MF Complete: protein homodimerization activity, iron ion transmembrane transporter activity, cadmium ion transmembrane transporter activity, manganese ion transmembrane transporter activity, metal cation:proton antiporter activity
GO BP Complete: multicellular organismal-level iron ion homeostasis, vacuolar acidification, positive regulation of transcription by RNA polymerase II, L-arginine transmembrane transport, macrophage activation, defense response to protozoan, intracellular iron ion homeostasis, inflammatory response, wound healing, nitrite transport, positive regulation of type II interferon production, antigen processing and presentation of peptide antigen, establishment of localization in cell, defense response to Gram-negative bacterium, response to type II interferon, proton transmembrane transport, respiratory burst, manganese ion transport, MHC class II biosynthetic process, cadmium ion transmembrane transport, manganese ion transmembrane transport, iron ion transport, mRNA stabilization, T cell proliferation involved in immune response, positive regulation of dendritic cell antigen processing and presentation, phagocytosis, positive regulation of T-helper 1 type immune response, response to lipopolysaccharide, negative regulation of cytokine production, positive regulation of phagocytosis, cellular detoxification of cadmium ion, iron ion transmembrane transport
GO CC Complete: late endosome membrane, phagocytic vesicle membrane, endosome membrane, lysosomal membrane, plasma membrane, tertiary granule membrane
Reactome Pathways: -