PANTHER Gene Information   
Gene Symbol(s): SLC11A1
Organism: Ornithorhynchus anatinus
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Gene Name: Solute carrier family 11 member 1
Gene ID: ENSOANG00000007050.3
Protein ID: A0A6I8NGA1
Persistent Id: PTN000194454
Alternate Ids:
A0A6I8NGA1(Synonym) ENSOANG00000007050(Ensembl)
A0A6I8NGA1_ORNAN(UniProtKB-ID) ENSOANP00000040107(Ensembl_PRO)
ENSOANT00000048489(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER (PTHR11706)
PANTHER Subfamily: NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 1 (PTHR11706:SF52)  
PANTHER GO-slim Molecular Function: metal cation:proton antiporter activity
PANTHER GO-slim Biological Process: iron ion transmembrane transport
PANTHER GO-slim Cellular Component: lysosomal membrane
endosome membrane
plasma membrane
phagocytic vesicle
PANTHER protein class: secondary carrier transporter
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein homodimerization activity, transition metal ion transmembrane transporter activity, iron ion transmembrane transporter activity, cadmium ion transmembrane transporter activity, manganese ion transmembrane transporter activity, metal ion transmembrane transporter activity, metal cation:proton antiporter activity
GO BP Complete: multicellular organismal-level iron ion homeostasis, vacuolar acidification, positive regulation of transcription by RNA polymerase II, L-arginine transmembrane transport, macrophage activation, defense response to protozoan, intracellular iron ion homeostasis, inflammatory response, wound healing, nitrite transport, positive regulation of type II interferon production, antigen processing and presentation of peptide antigen, metal ion transport, establishment of localization in cell, defense response to Gram-negative bacterium, response to type II interferon, proton transmembrane transport, respiratory burst, defense response to bacterium, response to bacterium, manganese ion transport, MHC class II biosynthetic process, cadmium ion transmembrane transport, manganese ion transmembrane transport, iron ion transport, positive regulation of gene expression, mRNA stabilization, T cell proliferation involved in immune response, positive regulation of dendritic cell antigen processing and presentation, phagocytosis, positive regulation of T-helper 1 type immune response, response to lipopolysaccharide, negative regulation of cytokine production, positive regulation of phagocytosis, positive regulation of cytokine production, cellular detoxification of cadmium ion, iron ion transmembrane transport
GO CC Complete: late endosome membrane, endosome, membrane, late endosome, phagocytic vesicle membrane, endosome membrane, lysosomal membrane, plasma membrane, tertiary granule membrane, lysosome
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs